Gene Information

Name : HPSH112_04425 (HPSH112_04425)
Accession : YP_006227579.1
Strain : Helicobacter pylori Shi112
Genome accession: NC_017741
Putative virulence/resistance : Virulence
Product : cag pathogenicity island protein cag alpha
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 894579 - 895571 bp
Length : 993 bp
Strand : +
Note : COG0630 Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis

DNA sequence : 
ATGACTGAAGACAGATTGAGTGCAGAAGATAAAAAATTTCTAGAAGTAGAAAGAGCTTTAAAAGAAGCGGCATTAAATCC
TTTAAGGCATGCTACTGAAGAACTTTTTGGTGATTTTTTAAAAATGGAAAATATCACTGAGATTTGTTACAATGGGAACA
AAGTTGTATGGGTTTTAAAAAATAATGGCGAATGGCAACCATTTGATGTGAGAGACAAGAAAGCCTTTAGTCTATCTCGT
TTAATGCATTTTGCTCGGTGTTGTGCAAGTTTTAAGAAAAAAACAATAGACAACTATGAAAATCCTATTTTGAGCAGCAA
TTTAGCGAATGGTGAAAGGGTGCAAATTGTCCTTTCCCCTGTTACAGTTAATGATGAAACCATTTCCATATCCATAAGGA
TACCTAGCAAAACAACCTATCCTCATAGCTTCTTTGAAGAACAGGGTTTTTATAATCTACTAGATAACAAAGAACAAGCG
ATCAGCGCGATTAAAGATGGTATTGCTATCGGTAAGAATGTGATTGTTTGTGGTGGCACAGGAAGCGGTAAGACGACTTA
TATCAAAAGCATCATGGAGTTTATCCCTAAAGAAGAAAGGATCATATCCATTGAAGACACCGAAGAGATTGTATTCAAAC
ACCACAAGAACTACACACAGCTTTTTTTTGGTGGGAATATCACCTCTGCTGATTGTTTAAAGTCATGTTTGAGAATGCGA
CCTGATAGAATCATTTTAGGAGAACTCAGAAGCAGTGAGGCATATGATTTTTATAACGTGCTTTGTAGCGGTCATAAAGG
CACGCTAACCACTCTACATGCAGGGAGCAGTGAAGAAGCGTTTATTCGTTTAGCCAACATGAGTTCATCTAATAACGCAG
CAAGGAATATCAAGTTTGAAAGCCTCATTGAGGGCTTTAGAGATTTAATTGATATGATTGTCCATATCAACCACCACAAA
CAGTGTGATGAATTTTATATCAAACATAGGTAG

Protein sequence : 
MTEDRLSAEDKKFLEVERALKEAALNPLRHATEELFGDFLKMENITEICYNGNKVVWVLKNNGEWQPFDVRDKKAFSLSR
LMHFARCCASFKKKTIDNYENPILSSNLANGERVQIVLSPVTVNDETISISIRIPSKTTYPHSFFEEQGFYNLLDNKEQA
ISAIKDGIAIGKNVIVCGGTGSGKTTYIKSIMEFIPKEERIISIEDTEEIVFKHHKNYTQLFFGGNITSADCLKSCLRMR
PDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLANMSSSNNAARNIKFESLIEGFRDLIDMIVHINHHK
QCDEFYIKHR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
HP0525 AAR03888.1 VirB11-like protein Virulence cag PAI Protein 1e-149 99
HP0525 BAD13886.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-149 99
HP0525 NP_207321.1 virB11-like protein Virulence cag PAI Protein 2e-149 99
HP0525 AAR03948.1 VirB11-like protein Virulence cag PAI Protein 1e-149 99
HP0525 AAR03917.1 VirB11-like protein Virulence cag PAI Protein 2e-149 99
virB11-4 YP_003728739.1 cag pathogenicity island protein alpha Virulence cag PAI Protein 2e-149 99
virB11 AGC69807.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
HP0525 AAR03859.1 VirB11-like protein Virulence cag PAI Protein 2e-149 99
virB11-2 YP_005779065.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
HP0525 BAD13831.1 cag pathogenicity island protein Virulence cag PAI Protein 9e-150 99
HP0525 BAD13777.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
virB11-2 YP_005775728.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
HP0525 BAD13941.1 cag pathogenicity island protein Virulence cag PAI Protein 9e-150 99
HP0525 BAD13804.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
HP0525 BAD14050.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
virB11-2 YP_005777269.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-148 99
HP0525 BAD13996.1 cag pathogenicity island protein Virulence cag PAI Protein 1e-149 99
HP0525 BAD13858.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-148 99
virB11-2 YP_005774544.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-149 99
cag-alfa AAF80196.1 Cag-alfa Virulence cag PAI Protein 1e-149 99
HP0525 BAD14024.1 cag pathogenicity island protein Virulence cag PAI Protein 6e-149 99
virB11_1 NP_223192.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 2e-149 99
HP0525 BAD13968.1 cag pathogenicity island protein Virulence cag PAI Protein 2e-147 98
HP0525 BAD13913.1 cag pathogenicity island protein Virulence cag PAI Protein 3e-148 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSH112_04425 YP_006227579.1 cag pathogenicity island protein cag alpha VFG0285 Protein 6e-150 99