Gene Information

Name : ureB (HPSH112_00350)
Accession : YP_006226801.1
Strain : Helicobacter pylori Shi112
Genome accession: NC_017741
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 67851 - 69560 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGCTTCTATGTATGGCCCTACTACAGGCGATAAAGTGAGATTGGGCGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATCTATGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACTTTAAGAGAAG
GCATGAGCCAATCCAACAACCCCAGCAAAGAAGAACTGGATTTAATCATCACTAACGCTTTAATCGTGGATTATACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGATGGCAAAATCGCTGGCATTGGCAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCCTTAGCTGGTGAAGGTTTGATCGTAACTGCTGGTGGTATTG
ACACACACATCCACTTCATCTCTCCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACGATGATTGGTGGCGGA
ACTGGCCCTGCTGATGGCACTAACGCAACCACTATCACTCCAGGCAGAAGAAATTTAAAATTTATACTCAGAGCGGCTGA
AGAATACTCCATGAACTTAGGTTTCTTGGCTAAAGGTAACGCTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGTCTTAAAATCCACGAAGACTGGGGAACAACTCCTTCTGCAATCAACCATGCGTTAGATGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCCGGTTGTGTAGAAGACACTATGGCAGCTATTGCCGG
ACGCACTATGCACACTTACCACACTGAAGGCGCTGGCGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATTCTGCCCGCTTCCACTAACCCCACTATCCCTTTCACTGTGAATACAGAAGCAGAGCACATGGACATGCTTATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATTCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACTAGTTCTGACTCTCAAGCTATGGGTCGTGTGGGTGAAGTTATCA
CCAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCAGCATTCTTTGGCGTAAAACCCAACATGATCATCAAAGGCGGGT
TCATTGCGTTAAGTCAAATGGGTGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CATCATGGTAAAGCCAAATACGATGCAAACATCACTTTTGTATCCCAAGCGGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAACATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATTCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCGCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYASMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKFILRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGLKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTYHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNSETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-158 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-158 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-145 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-145 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-145 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-145 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_006226801.1 urease subunit beta VFG0270 Protein 0.0 99