Gene Information

Name : guaA (HPSH417_04915)
Accession : YP_006224612.1
Strain : Helicobacter pylori Shi417
Genome accession: NC_017739
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1025084 - 1026610 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGTGGGATTTATGCAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCCAATGGAAAAATCTTTGATTTGGATTTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGGGTAGTGGCTTGCACGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CACTCAAGATTCTGTGATTTTTGAAGGCGTGAAAATTAAAAGCCTTGTGTGGATGAGTCATATGGATAAAGTCATAGAAT
TGCCTAAAGGCTTCACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGTGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGCGGTTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATGGCGCGCTTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTTGCTACGCTATTGCACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTAGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAAAGTTCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGACGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAGAAGCACCATTTAAAAGGTAAAATTGAGTTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAAGTGATCAAAACCCACCATAATGTGGGCGGATT
GCCTGAATGGATGGACTTCAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTCCGTTTGTTGGGTAAGGAAT
TGGGCATTAGCCAGGATTTTTTAATGCGTCACCCCTTTCCAGGGCCTGGACTTGCGATAAGGATTTTAGGCGAAGTCAGC
GAGAGTAAGATCAGATGCTTGCAAGAAGCGGATTTTATTTTTATAGAAGAGCTTAAAAAAGCCAATTTGTATGACAAGGT
TTGGCAGGCTTTTTGCGTGCTGTTGAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACTTATGAAAACGCTATTT
GTTTAAGGGCGGTGAATGCGAGCGATGGCATGACGGCGAGCTTTTCATTTTTGGAGCATTCTTTTTTAGAAAAGGTTTCT
AATCGCATCACTAATGAAGTGAGCGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYAEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPNGKIFDLDLPILGICYG
MQYLVDFFGGVVACTNEQEFGKAVLEITQDSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREMARLKEKIANAKVLCAVSGGVDSTVVATLLHRAIKDNLIAV
FVDHGLLRKNEKEKVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGISQDFLMRHPFPGPGLAIRILGEVS
ESKIRCLQEADFIFIEELKKANLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVSGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 9e-134 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 8e-134 53
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 1e-133 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-115 48