Gene Information

Name : HPSH417_02495 (HPSH417_02495)
Accession : YP_006224146.1
Strain : Helicobacter pylori Shi417
Genome accession: NC_017739
Putative virulence/resistance : Virulence
Product : CAG pathogenicity island protein 5
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 498676 - 500922 bp
Length : 2247 bp
Strand : -
Note : COG3505 Type IV secretory pathway, VirD4 components

DNA sequence :
ATGGAAGACTTTTTATATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTCTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAACCAACCTCAAAAGAAAA
AAAACTTTAAAGAAATCATTATAGAGGGGCTGAAAGAAAGAGTTAAAACCTTTGGCTTTTGGTTACAAGCTATACTATTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGACAATAAATTGCCTGA
GAGTGATGATGATCTTTTTGATATATGGATCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCGCTTTGTTTTA
GTTCACTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAGAGCGAAGAAAAAATGATCAAAGCTAAACTTATCACACCCAATAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTAGGCAGGCGTGGTTTAGGGGATTTTATCGCTTATGCAGGACAGGCGTTCATTGGCTTGATCGCTCCTACC
AGAAGCGGTAAGGGTGTGGGTTTCATCATGCCCAACATGATCAATTACCCTCAAAATATCGTTGTGTTTGACCCTAAAGC
TGACACTATGGAAACTTGCGGAAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTATATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACGCGCCTAAAAGGTCATGGGATGGTGGCTAGTGGGGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGTTGGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAGGCGCGAAATCTTTTTGTCATCAATTGCAATATTT
ATAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCCGAAACCCCCACGATG
TTTTTCATCGGTTCTATGGCGAGCGGTATCAACTTGATTGATGAAAACACAAACATGGAAAAAGTTGTGTCTCTGATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGACAATCTAAGAGTGCTTAGTCCTGCTACTAGAAACATGTGGAACAACT
TCAAAACAATGGGTGGCGCTAAAGAAACTTATAGCTCTGTTCAAGGGGTCTATACTTCAGCGTTTGCGCCTTACAATAAC
GCCATGATCAGGAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTGAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATATTAGAGCTGTTTTTCAATGTGATGATTTATAGCAACCTTATTC
TGCCAATCCATGATCCGCAATGCAAAAGAAGTTGTTTGATGCTTATGGATGAGTTCACGCTCTGTGGCTATTTAGAAACC
TTTGTGAAAGCGGTAGGGATTATGGCAGAATACAACATGCGCCCTGCCTTTGTGTTTCAAAGTAAGGCGCAACTAGAGAA
TGACCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTAAATATGTATTATGGGATTA
ACAACGATAACTACTATGAACATTTTGAAAAACTTTCTAAGGTGTTGGGGAAATACACAAGGCAAGACGTGAGTCGAAGC
ATTGATGATAATACCGGTAAGACCAACACTTCTATCAGCAACAAAGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
CATGGGCGATGAGCTTATCATTTTAGAAAACACGCTCAAACCCATCAAATGCCACAAGGCACTCTACTATGATGATCCGT
TCTTCACTGATGAACTCATTAAGGTAAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTAATCAAGCAACT
TTCTATGATGATTTGCAAGCCGCTAAAACTAGAGGCGAATTGAGCTATGACAAGTCTTTAGTGCCTGTGGGTTCAAGCGA
ATTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKNFKEIIIEGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNKLPESDDDLFDIWIYAIQDFPAYYFKALCFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWESEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVYIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDENTNMEKVVSLMEFFGGEEDKSGDNLRVLSPATRNMWNNFKTMGGAKETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTRGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 98
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPSH417_02495 YP_006224146.1 CAG pathogenicity island protein 5 VFG0284 Protein 0.0 99