Gene Information

Name : ureB (HCW_02470)
Accession : YP_006222405.1
Strain : Helicobacter cetorum MIT 00-7128
Genome accession: NC_017737
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 511866 - 513575 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTTCAAGAAAAGAATACGCATCAATGTATGGCCCAACTACAGGCGATAAAGTAAGATTGGGTGATACAGA
ACTTATTGCTGAAGTAGAGCATGACTTTACTATCTATGGTGAAGAGCTTAAATTTGGTGGCGGTAAAACTTTAAGAGAAG
GCATGAGCCAATCTAACAATCCTAGCAAGGAAGAATTAGATTTAATCATCACTAACGCTTTAATTGTAGATTACACCGGT
ATTTATAAAGCTGATATTGGTATCAAAGATGGTAAAATCACTGGTATTGGTAAAGGCGGAAATAAAGACATGCAAGATGG
TGTTAAGAACAATCTTTGCGTAGGTCCTGCTACTGAAGCTCTAGCTGCTGAAGGTTTGATTGTAACTGCTGGTGGAATTG
ACACTCACATTCACTTCATCTCTCCTCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACCACTATGATTGGTGGAGGA
ACTGGTCCTGCTGATGGAACAAACGCTACAACCATTACTCCAGGCAGAAGAAATTTAAAGTGGATGCTTAGAGCTGCAGA
AGAATATTCTATGAACTTAGGTTTCTTAGGTAAAGGTAATGCCTCTAATGACGCATGCTTAGCTGACCAAATTGAGGCGG
GCGCAATTGGCTTTAAAATCCACGAAGACTGGGGCACAACTCCATCTGCAATCAACCATGCTTTAGACATTGCTGATAAA
TATGATGTTCAAGTAGCTATCCATACTGATACTTTGAATGAGGCAGGTTGCGTAGAAGACACTATGGCTGCCATTGCTGG
ACGCACAATGCACACATTCCACACTGAAGGTGCTGGTGGAGGACACGCTCCTGATATCATTAAAGTAGCTGGTGAGCATA
ATATTTTACCTGCTTCAACTAATCCTACTATTCCTTTCACAGTGAATACTGAGGCAGAGCATATGGATATGTTAATGGTT
TGCCACCACTTAGATAAAAGCATTAAAGAAGATGTTCAGTTTGCAGATTCTAGAATCCGCCCTCAAACTATTGCAGCAGA
AGATGCTTTGCATGACATGGGAATTTTCTCCATCACAAGTTCTGACTCACAAGCTATGGGGCGTGTAGGTGAAGTTATCA
CTAGAACTTGGCAAACTGCTGATAAGAACAAAAAAGAGTTTGGCCGCTTGAAAGAAGAAACAGGCGATAATGACAACTTT
AGGATCAAGCGCTATTTGTCTAAATACACTATTAACCCAGCGATTGCTCATGGTATTAGTGAGTATGTTGGTTCTGTAGA
AGTAGGCAAAGTAGCTGACTTAGTATTATGGAGCCCAGCATTCTTTGGTGTTAAACCAAACATGATTATTAAGGGTGGTT
TCATTGCTCTTTCTCAAATGGGTGATGCTAACGCTTCTATTCCTACCCCTCAACCTGTATATTACAGAGAGATGTTTGCT
CATCATGGTAAAGCTAAGTATGATGCAAATATCACTTTTGTATCTCAAGCAGCTTATGAAAATGGTATTAAAGAAGAGTT
AGGACTTGAAAGACAAGTATTGCCGGTTAAAAATTGCAGAAATATCACTAAAAAAGATATGCAATTTAACGACACTACCG
CTCATATTGAAGTTAACCCTGAGACTTACCATGTGCATGTAGATGGCAAAGAAGTAACTTCTAAAGCCGCTACTGAGGTA
AGCTTGGCACAACTCTTTAATATTTTCTAA

Protein sequence :
MKKISRKEYASMYGPTTGDKVRLGDTELIAEVEHDFTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKITGIGKGGNKDMQDGVKNNLCVGPATEALAAEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLGKGNASNDACLADQIEAGAIGFKIHEDWGTTPSAINHALDIADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDALHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEETGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQAAYENGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVHVDGKEVTSKAATEV
SLAQLFNIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-156 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-156 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-148 61
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-148 61
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 2e-148 61
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 2e-148 61

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_006222405.1 urease subunit beta VFG0270 Protein 0.0 97