Gene Information

Name : fliI (HCW_01880)
Accession : YP_006222291.1
Strain : Helicobacter cetorum MIT 00-7128
Genome accession: NC_017737
Putative virulence/resistance : Virulence
Product : flagellum-specific ATP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.14
Position : 386640 - 387962 bp
Length : 1323 bp
Strand : +
Note : COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
ATGCCCCTAAAATCGCTTAAAAACCGCTTGAATCAAAATTTTGATTTATCGCCCCGCTATGGGAGTGTGAAAAAAATCAT
GCCAAATATCGTTTATGCGAATGGTTTTAACCCATCAGTGGGCGATGTGGTTAAAATTGAGAAAAGCGATGGCACAGAAT
GCGTGGGAATGGTCGTGGTGGTAGAAAAAGAGCAATTTGGTTTCACGCCCTTTAGTTTTATAGAAGGCACTAGAGCTGGC
GATAAAGTGCTGTTTTTAAAAGAGGGACTGACTTTTCCTGTGGGTCGTAATCTTTTAGGAAGAGTGCTAAACCCTTTAGG
ACAAGCCATTGATAATAAGGGGGCATTAGATTATGAGAGCCTAGCTCCTGTGATTACTACTCCTATTGCCCCCTTAAAAA
GAGGCTTGATTGATGAGGTTTTTAGCGTGGGGGTAAAGAGCATTGATGGGCTTTTGACTTGTGGTAAGGGGCAAAAACTA
GGTATTTTTGCAGGTTCTGGGGTGGGTAAATCCACTTTAATGGGCATGATTACTAGGGGTTGTGCGGCACAAATTAAAGT
GATTGCTCTAATAGGCGAAAGGGGTAGAGAAATACCTGAATTTATAGAAAAGAATCTCAAAGGGGATTTAAGCTCTTGTG
TGCTGATTGTTGCCACAAGCGATGATAGCCCTTTAATGCGAAAATATGGGGCGTTTTGTGCGATGAGCGTGGCGGAGTAT
TTTAAAAATCAAGGGTTAGATGTGTTGTTTATGATGGATTCGGTTACTCGTTTTGCTATGGCTCAAAGAGAAATCGGTCT
GTCCTTAGGCGAACCGCCCACTTCCAAAGGCTACCCCCCATCGGCACTTTCATTATTACCCCAGCTTATGGAAAGAGCTG
GCAAAGAAGAGGGCAAGGGAAGTATTACCGCCTTTTTTAGCGTGCTAGTAGAGGGCGATGATTTAAGCGACCCTATAGCT
GACCAAGCCAGAAGTATTTTAGATGGGCATATTGTCCTAAGTAGGGAGCTAACCGATTATGGTATCTATCCGCCTATCAA
TATCCTCAACTCCGCATCAAGGGTAGCTAGAGATATAACAAGCGAGTCTCAAAACCTAAATGCGAGAAAATTCCGCCGTT
TGTATGCGTTATTGAAAGAAAATGAAATGCTCATTCGTATCGGCTCTTATCAAATGGGAAATGATAGAGAACTTGATGAA
GCGATTAATAAAAAGGCTTTAATGGAGCAATTTTTAATGCAAGATGAAAACGCCTTACAACCTTTTGAAAAAAGCTTTAA
AGAGCTAGAAGAAATCTTACAAACCCCCCAAAAAGGAATATAG

Protein sequence :
MPLKSLKNRLNQNFDLSPRYGSVKKIMPNIVYANGFNPSVGDVVKIEKSDGTECVGMVVVVEKEQFGFTPFSFIEGTRAG
DKVLFLKEGLTFPVGRNLLGRVLNPLGQAIDNKGALDYESLAPVITTPIAPLKRGLIDEVFSVGVKSIDGLLTCGKGQKL
GIFAGSGVGKSTLMGMITRGCAAQIKVIALIGERGREIPEFIEKNLKGDLSSCVLIVATSDDSPLMRKYGAFCAMSVAEY
FKNQGLDVLFMMDSVTRFAMAQREIGLSLGEPPTSKGYPPSALSLLPQLMERAGKEEGKGSITAFFSVLVEGDDLSDPIA
DQARSILDGHIVLSRELTDYGIYPPINILNSASRVARDITSESQNLNARKFRRLYALLKENEMLIRIGSYQMGNDRELDE
AINKKALMEQFLMQDENALQPFEKSFKELEEILQTPQKGI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
lscN AAO18044.1 LscN Virulence TTSS locus Protein 1e-73 49
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-79 46
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-79 46
escN AAC31513.1 L0034 Virulence LEE Protein 7e-80 46
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 7e-80 46
unnamed AAL06369.1 EscN Virulence LEE Protein 2e-78 45
escN AAC38383.1 EscN Virulence LEE Protein 9e-80 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-83 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-82 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 5e-82 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-80 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 7e-82 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 7e-81 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 5e-82 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 1e-78 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-79 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 2e-78 44
escN AAK26715.1 EscN Virulence LEE Protein 4e-78 44
escN AAL57542.1 EscN Virulence LEE Protein 4e-78 44
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 3e-55 44
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 2e-55 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 43
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-79 43
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 1e-54 43
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 1e-54 43
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-59 43
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 1e-54 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-69 42
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-69 42
escN CAI43874.1 EscN protein Virulence LEE Protein 7e-79 41
escN YP_003223475.1 translocator EscN Virulence LEE Protein 1e-78 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliI YP_006222291.1 flagellum-specific ATP synthase VFG0390 Protein 1e-79 51
fliI YP_006222291.1 flagellum-specific ATP synthase VFG0048 Protein 2e-78 50
fliI YP_006222291.1 flagellum-specific ATP synthase VFG0192 Protein 7e-78 50
fliI YP_006222291.1 flagellum-specific ATP synthase VFG2144 Protein 1e-77 47
fliI YP_006222291.1 flagellum-specific ATP synthase VFG0812 Protein 4e-80 46
fliI YP_006222291.1 flagellum-specific ATP synthase VFG1254 Protein 2e-79 45
fliI YP_006222291.1 flagellum-specific ATP synthase VFG0730 Protein 5e-80 45
fliI YP_006222291.1 flagellum-specific ATP synthase VFG2331 Protein 5e-72 43
fliI YP_006222291.1 flagellum-specific ATP synthase VFG2499 Protein 2e-76 43
fliI YP_006222291.1 flagellum-specific ATP synthase VFG1008 Protein 4e-60 42
fliI YP_006222291.1 flagellum-specific ATP synthase VFG1778 Protein 4e-57 41