Gene Information

Name : ureB (HCW_07950)
Accession : YP_006223477.1
Strain : Helicobacter cetorum MIT 00-7128
Genome accession: NC_017737
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 1740841 - 1742550 bp
Length : 1710 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAATGAAAAAACTTGATTATGTCAATACTTATGGGCCTACTAAGGGGGATAAAGTAAGACTCGGCGATACTGAGCT
TTGGGCAGAAGTTGAGCATGACTATACAATCTATGGCGAAGAGTTAAAATTTGGTGCGGGCAAAACCATTAGAGAAGGCA
TGGGACAATCTAATAGCCATGATGAAAACACTTTGGATTTAGTGATTACAAACGCTTTGATTATTGACTACACCGGCATT
TACAAAGCTGATATTGGGATTAAAAACGGCAAAATCCACGGCATTGGAAAAGCTGGGAATAAAGACATGCAAGATGGCGT
TAGCCCTAATTTAGTCGTAGGTGTAGGCACAGAAGCTTTAGCGGGAGAAGGCATGATTATTACAGCTGGTGGGATTGATA
GCCACACGCATTTCTTGAGTCCGCAACAATTTCCCACAGCCCTAGCTAATGGTGTAACCACAATGTTTGGTGGCGGAACA
GGTCCAGTTGATGGCACAAACGCTACAACCATTACTCCGGGTGAGTGGAATATCCACAGAATGTTAAGAGCCGCTGAAGA
ATACGCTATGAATATAGGATTTTTAGGAAAAGGCAATTCTTCTAGCAAACAGCAATTAGTGGAGCAAATCCATGCAGGGG
TTATTGGTTTTAAATTACACGAAGACTGGGGCACTACACCGAGCGCGATTGATACTTGCTTAAGTATTGCCGATGAGTAT
GATGTGCAAGTGTGCATCCATACAGACACCGTGAATGAAGCTGGGTATGTGAATGACACGCTCAATGCGATGAACGGACG
CGCCATTCATGCATACCACATTGAAGGGGCAGGTGGAGGACATAGCCCAGATGTTATCACTATGGCTGGTGAGGAAAACA
TCTTACCAAGTTCAACTACCCCGACCATTCCTTATACCATAAATACGGTTGCAGAACACTTAGACATGCTAATGACCTGC
CACCACTTGGATAAAAAAATTAGAGAGGATTTACAATTTTCACAAAGTCGTATCCGCCCAGGCTCTATTGCAGCTGAAGA
TGTCTTGCATGACAATGGCATGATTGCTATGACAAGTTCTGATTCTCAAGCTATGGGAAGAGCGGGGGAAGTCGTGCCTA
GAACTTGGCAAACCGCCGATAAAAACAAAAAAGAGTTTGGTCCTTTAAAAGAAGACGCTAAAAATGGGAATGATAATTTC
CGCATTAAACGCTATATTTCTAAATACACTATAAATCCTGCCATTACGCATGGCGTGAGTGAATACATCGGCTCTGTAGA
AACAGGAAAAATCGCTGATTTAGTCGTGTGGAATCCAGCCTTTTTTGGTGTGAAGCCTAAAATCATCATTAAAGGTGGCT
TGGTTGTATTCTCTGAAATGGGCGATAGCAACGCCTCTGTGCCAACCCCTCAACCTGTGTATTACAGAGAAATGTTTGGC
CATCATGGAAAGGCTAAATTTGATACTAGCATTACTTTTGTCAATAAGCTTGCCTATGAAAATGGCATTAAAGAAAAGCT
TGGCTTAGAAAGAAAAGTATTACCCATTAAAAATTGTCGCAATGTAACTAAGAAAGACTTTAAGTTTAATAACACAACAG
GGAAACTCAGCGTAGACCCAGAGAGCTTTGAAGTCTTTTTGGATGGTAAGCTTTGTGTCTCTAAACCAGCGAGCGAACTA
CCCTTAGCCCAACGCTATACTTTCTTCTAA

Protein sequence :
MKMKKLDYVNTYGPTKGDKVRLGDTELWAEVEHDYTIYGEELKFGAGKTIREGMGQSNSHDENTLDLVITNALIIDYTGI
YKADIGIKNGKIHGIGKAGNKDMQDGVSPNLVVGVGTEALAGEGMIITAGGIDSHTHFLSPQQFPTALANGVTTMFGGGT
GPVDGTNATTITPGEWNIHRMLRAAEEYAMNIGFLGKGNSSSKQQLVEQIHAGVIGFKLHEDWGTTPSAIDTCLSIADEY
DVQVCIHTDTVNEAGYVNDTLNAMNGRAIHAYHIEGAGGGHSPDVITMAGEENILPSSTTPTIPYTINTVAEHLDMLMTC
HHLDKKIREDLQFSQSRIRPGSIAAEDVLHDNGMIAMTSSDSQAMGRAGEVVPRTWQTADKNKKEFGPLKEDAKNGNDNF
RIKRYISKYTINPAITHGVSEYIGSVETGKIADLVVWNPAFFGVKPKIIIKGGLVVFSEMGDSNASVPTPQPVYYREMFG
HHGKAKFDTSITFVNKLAYENGIKEKLGLERKVLPIKNCRNVTKKDFKFNNTTGKLSVDPESFEVFLDGKLCVSKPASEL
PLAQRYTFF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 1e-146 58
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 1e-146 58
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-141 57
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 1e-141 57
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-141 57
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 1e-141 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_006223477.1 urease subunit beta VFG0270 Protein 0.0 72