Gene Information

Name : ureB (HCD_03585)
Accession : YP_006220943.1
Strain : Helicobacter cetorum MIT 99-5656
Genome accession: NC_017735
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 761575 - 763284 bp
Length : 1710 bp
Strand : +
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGTAGAAAAGAATACGCATCTATGTATGGTCCCACTACTGGCGATAAAGTGAGATTGGGCGATACAGA
ACTTATTGCTGAAGTAGAACACGACTACACTATTTATGGTGAAGAGCTTAAATTTGGTGGCGGTAAAACTTTAAGAGAAG
GCATGAGTCAGTCTAATAATCCTAGCAAGGAAGAGTTAGATTTAATCATCACTAACTGCCTAATCGTAGATTATACCGGT
ATCTATAAGGCTGATATTGGCATTAAGGATGGCAAAATCGCTGGCATTGGTAAGGGCGGAAACAAGGATATGCAAGATGG
CGTTAAAAACAATCTTTGCGTAGGTCCTGCTACTGAAGCGTTAGCTGGCGAAGGCTTGATTGTTACTGCAGGTGGGATTG
ATACACATATCCACTTCATTTCTCCGCAACAAATTCCTACAGCTTTTGCAAGCGGTGTAACTACTATGATTGGTGGAGGC
ACAGGTCCTGCTGATGGAACAAACGCTACAACCATTACTCCGGGCAGAAGAAATTTAAAGTGGATGCTAAGAGCCGCAGA
AGAATATTCTATGAACTTAGGTTTCTTAGGTAAAGGTAATGCCTCTAATGACGCATGCTTAGCTGATCAAATTGAGGCGG
GTGCGATTGGCTTTAAAATCCACGAAGACTGGGGCACAACTCCATCTGCAATCAACCATGCTTTAGACATTGCTGATAAA
TATGATGTTCAAGTGGCCATCCATACAGATACTTTAAATGAAGCAGGTTGTGTAGAAGACACTATGGCTGCCATTGCTGG
ACGCACAATGCATACATTCCACACTGAAGGTGCTGGTGGAGGACACGCTCCTGATATCATTAAAGTAGCTGGTGAGCATA
ATATTCTACCTGCTTCAACTAACCCTACTATTCCTTTCACAGTGAATACTGAAGCAGAGCATATGGATATGTTGATGGTT
TGCCACCACTTAGATAAGAGCATTAAAGAAGATGTTCAGTTCGCTGATTCAAGAATCCGCCCCCAAACCATTGCGGCTGA
AGATGCTTTGCATGACATGGGAATTTTCTCTATTACAAGTTCGGACTCACAAGCTATGGGTCGTGTGGGTGAAGTTATCA
CTAGAACTTGGCAAACCGCTGATAAAAACAAAAAAGAGTTTGGTCGCTTGAAAGAAGAAAAGGGCGATAATGATAACTTT
AGAATCAAACGCTACTTGTCTAAATACACTATTAACCCAGCGATTGCTCATGGCATTAGTGAGTATGTTGGTTCTGTAGA
AGTAGGCAAGGTGGCTGACTTAGTATTGTGGAGTCCAGCATTCTTTGGTGTGAAGCCAAACATGATTATTAAGGGTGGTT
TCATCGCTCTTTCTCAAATGGGTGATGCAAACGCTTCTATTCCTACCCCTCAACCTGTATATTACAGAGAGATGTTTGCT
CATCATGGTAAAGCTAAGTATGATGCAAATATCACTTTTGTATCTCAAGTAGCTTATGAAAACGGCATTAAAGAAGAGTT
AGGACTTGAAAGACAAGTATTACCAGTTAAAAATTGCAGAAATATCACTAAAAAGGACATGCAATTTAATGACACTACCG
CTCATATTGAAGTCAACCCTGAAACCTACCATGTGCATGTAGATGGCAAAGAAGTAACTTCTAAAGCGGCCGATAAAGTA
AGCTTGGCCCAACTCTTTAGTATTTTCTAG

Protein sequence :
MKKISRKEYASMYGPTTGDKVRLGDTELIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNCLIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLCVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLGKGNASNDACLADQIEAGAIGFKIHEDWGTTPSAINHALDIADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDALHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQVAYENGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVHVDGKEVTSKAADKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 3e-154 62
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 3e-154 62
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-147 60
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-147 60
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 4e-147 60
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 4e-147 60

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_006220943.1 urease subunit beta VFG0270 Protein 0.0 98