Gene Information

Name : guaA (HPB14_04855)
Accession : YP_006219680.1
Strain : Helicobacter pylori HUP-B14
Genome accession: NC_017733
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.5.2
Position : 1023850 - 1025376 bp
Length : 1527 bp
Strand : -
Note : COG0518 GMP synthase - Glutamine amidotransferase domain

DNA sequence :
ATGATTTTAGTATTAGATTTTGGGAGCCAATACACACAGCTGATTGCTAGAAGATTGAGAGAGAGCGGGATTTATACAGA
AATAGTCCCTTTTTTTGAAAGCATAGAAAACATTCAAAAAAAAGCCCCTAAAGGTTTGATTTTGAGTGGGGGGCCAGCGA
GCGTGTATGCTAAAGACGCTTACAAGCCTAACGAGAAAATCTTTGATTTGAATGTGCCGATTTTAGGGATTTGCTACGGC
ATGCAGTATTTGGTGGATTTTTTTGGGGGCGTGGTGGCTTGTGCGAATGAGCAAGAATTTGGTAAGGCTGTTTTAGAAAT
CGCTCAAAATTCCGTGATTTTTGAAGGCGTGAAGATTAAAAGCCTTGTGTGGATGAGTCATATGGATAAAGTCATAGAAC
TGCCTAAAGGCTTTACTACCCTTGCAAAAAGCCCTAATTCCCCCCATTGCGCGATTGAAAACGGCAAGATTTTTGGCTTG
CAATTCCACCCAGAAGTCATTCAAAGCGAAGAAGGGGGTAAGATTTTAGAAAATTTTGCCCTTTTGGTTTGCGGCTGTGA
AAAAACTTGGGGGATGCAGCATTTCGCTCAAAGAGAAATCGCGCGATTGAAAGAAAAAATTGCTAACGCTAAGGTTTTGT
GCGCGGTGAGTGGGGGCGTGGATTCTACGGTGGTCGCTACGCTATTATACAGAGCCATTAAGGATAATTTGATCGCTGTT
TTTGTAGATCATGGCTTGTTGCGTAAAAATGAAAAAGAAAGAGTGCAAGCGATGTTTAAAGACTTGCAAATCCCTTTAAA
CACGATAGATGCTAAAGAAATCTTTTTGTCTAAATTAAAGGGCGTGAGCGAGCCTGAATTGAAGCGAAAAATCATCGGCG
AAACCTTTATTGAAGTGTTTGAAAAAGAAGCCAAAAAGCACCATTTAAAAGGCAAAATTGAATTTTTAGCCCAAGGCACT
TTATACCCTGATGTGATTGAATCCGTGAGCGTTAAAGGGCCTTCAAAGGTGATCAAAACCCACCATAATGTGGGCGGACT
GCCTGAATGGATGGATTTTAAACTCATAGAGCCTTTAAGGGAATTGTTTAAAGATGAGGTGCGTTTGTTGGGTAAGGAAT
TGGGCGTTAGCCAGGATTTTTTAATGCGCCACCCTTTTCCAGGGCCTGGGCTTGCTGTAAGGATTTTAGGCGAGGTTAGT
GAGGATAAAATCAAATGCTTGCAAGAAGCGGATGCTATTTTTATAGAGGAGCTTAAAAAAGCCCATTTGTATGACAAGGT
TTGGCAAGCTTTTTGCGTGCTATTGAATGTCAATTCTGTGGGGGTTATGGGGGATAATCGCACTTATGAAAACGCTATTT
GCTTAAGAGCGGTGAATGCGAGCGATGGCATGACAGCGAGCTTTTCTTTTTTAGAGCATTCTTTTTTAGAAAAGGTTTCT
AACCGCATCACTAATGAAGTGAATGGTATCAATAGGGTGGTGTATGATATTACCTCTAAACCACCAGGAACGATTGAATG
GGAATGA

Protein sequence :
MILVLDFGSQYTQLIARRLRESGIYTEIVPFFESIENIQKKAPKGLILSGGPASVYAKDAYKPNEKIFDLNVPILGICYG
MQYLVDFFGGVVACANEQEFGKAVLEIAQNSVIFEGVKIKSLVWMSHMDKVIELPKGFTTLAKSPNSPHCAIENGKIFGL
QFHPEVIQSEEGGKILENFALLVCGCEKTWGMQHFAQREIARLKEKIANAKVLCAVSGGVDSTVVATLLYRAIKDNLIAV
FVDHGLLRKNEKERVQAMFKDLQIPLNTIDAKEIFLSKLKGVSEPELKRKIIGETFIEVFEKEAKKHHLKGKIEFLAQGT
LYPDVIESVSVKGPSKVIKTHHNVGGLPEWMDFKLIEPLRELFKDEVRLLGKELGVSQDFLMRHPFPGPGLAVRILGEVS
EDKIKCLQEADAIFIEELKKAHLYDKVWQAFCVLLNVNSVGVMGDNRTYENAICLRAVNASDGMTASFSFLEHSFLEKVS
NRITNEVNGINRVVYDITSKPPGTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-134 53
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-134 53
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 3e-134 53
guaA NP_938969.1 GMP synthase Not tested Not named Protein 4e-114 47