Gene Information

Name : HPB14_04055 (HPB14_04055)
Accession : YP_006219526.1
Strain : Helicobacter pylori HUP-B14
Genome accession: NC_017733
Putative virulence/resistance : Virulence
Product : CAG pathogenicity island protein 5
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 833548 - 835794 bp
Length : 2247 bp
Strand : -
Note : COG3505 Type IV secretory pathway, VirD4 components

DNA sequence :
ATGGAAGACTTTTTGTATAACACCTTATATTTCATAGAGGATTATAAGTTGGTTGTTATTTTTAGTTTCATAGGGTTAAT
AGCGTTATTTTTTCTTTACAAATTCATAAAAGCTCAAAAAAAGGCTTTTAAAGATAAAGCTAATCAGCCTCAAAAGAAAA
AAAGCTTTAAAGAAATCATTATAGATGGGCTGAAAGAAAGGGTTAAAACCTTTGGCTTTTGGTTGCAAGCTATACTCTTA
CTATCCTATTCTTTTATCACATCAGGGTTATTTTTCTTGATTCTCTTAGGTAATTTTTATGATGATAATCGATCGCCTGA
AAGTGATGATGATCTTTTTGATATATGGGTCTATGCGATACAAGATTTTCCTGCATACTATTTTAAGGCACTCACTTTTA
GCTCGCTCAAGATTTATGGGTTCAATATATCCTTAGTCGTATATAGTTCTATTTTATGCTCTTATATATTCATTACCTTT
TTTGTGTGGTTCTTAAAATACTTAACTCGGACTAGAGACATAGGAGCGAATAAAAAAGTTGATGATCTCTTTGGTAGCGC
GAGTTGGGAAACTGAAGAAAAAATGATCAAAGCCAAGCTTATCACACCCAACAATAAAAAACGCGCCTTTGACAAACGAG
AGGTTATTGTAGGCAGGCGTGGCTTGGGGGATTTTATCGCTTACGCAGGACAGGCGTTCATTGGCTTGATTGCTCCTACT
AGAAGCGGTAAAGGTGTGGGTTTCATCATGCCCAATATGATCAATTATCCTCAAAATATCGTTGTGTTTGACCCTAAGGC
TGACACTATGGAAACTTGCGGGAAAATCAGAGAAAAACGCTTCAACCAAAAAGTGTTCATCTATGAACCTTTCTCCTTAA
AAACACACCGATTTAATCCTTTCGCTTATGTGGATTTTGGTAATGATGTGGTTTTGACTGAAGACATACTCTCTCAAATT
GACACACGCTTAAAAGGGCATGGCATGGTGGCTAGTGGAGGGGATTTTTCCACTCAAATCTTTGGATTGGCTAAGTTAGT
GTTCCCTGAAAGACCTAATGAAAAAGATCCTTTTTTTAGCAATCAAGCGCGAAACCTCTTTGTCATCAATTGCAATATTT
ACAGGGATCTCATGTGGACTAAAAAGGGGCTTGAGTTTGTCAAAAGAAAAAAAATCATCATGCCTGAAACCCCTACGATG
TTTTTCATAGGCTCTATGGCAAGTGGGATCAACCTGATTGATGAAGACACAAACATGGAAAAAGTCGTGTCTTTAATGGA
ATTTTTTGGAGGTGAAGAAGATAAGAGTGGCGATAATCTAAGAGCGCTTAGTCCTGCCACTAGAAACATGTGGAATAACT
TTAAGACAATGGGTGGCGCTAGAGAAACTTATAGCTCTGTTCAAGGGGTATATACTTCAGCCTTTGCTCCTTATAATAAC
GCTATGATCAGAAATTTCACGAGCGCTAATGATTTTGATTTCAGGCGTTTAAGGATTGATGAAGTGAGTATTGGCGTGAT
CGCTAATCCTAAAGAAAGCACTATTGTTGGGCCGATACTAGAGCTGTTTTTTAACGTGATGATTTATAGCAACCTTATTC
TGCCAATCCATGATCCACAATGCAAAAGAAGTTGCTTAATGCTTATGGATGAATTCACGCTCTGTGGCTATTTAGAGACC
TTTGTTAAAGCGGTAGGGATCATGGCAGAATACAACATGCGCCCCGCTTTTGTGTTTCAAAGTAAGGCGCAATTAGAAAA
TGATCCCCCACTTGGTTATGGTAGGAATGGCGCTAAGACTATTTTAGACAACCTTTCTTTGAATATGTATTATGGAATCA
ACAACGATAACTACTATGAACATTTTGAAAAGCTTTCTAAAGTGTTAGGGAAATACACAAGGCAAGATGTGAGTAGGAGC
ATTGATGATAATACGGGTAAGACCAACACTTCTATCAGCAACAAGGAGCGGTTTTTGATGACCCCTGATGAATTGATGAC
TATGGGTGATGAGCTTATCATTTTAGAAAATACGCTCAAACCCATCAAATGCCACAAGGCGCTTTACTATGATGATCCTT
TCTTCACCGATGAGCTCATTAAGGTGAGTCCAAGCTTGAGCAAGAAATACAAATTGGGGAAAGTGCCTAATCAAGCAACT
TTTTACGATGACTTGCAAGCCGCCAAAACCAAAGGCGAATTGAGTTATGATAAATCTTTAGTGCCTGTGGGTTCAAGCGA
ACTGTGA

Protein sequence :
MEDFLYNTLYFIEDYKLVVIFSFIGLIALFFLYKFIKAQKKAFKDKANQPQKKKSFKEIIIDGLKERVKTFGFWLQAILL
LSYSFITSGLFFLILLGNFYDDNRSPESDDDLFDIWVYAIQDFPAYYFKALTFSSLKIYGFNISLVVYSSILCSYIFITF
FVWFLKYLTRTRDIGANKKVDDLFGSASWETEEKMIKAKLITPNNKKRAFDKREVIVGRRGLGDFIAYAGQAFIGLIAPT
RSGKGVGFIMPNMINYPQNIVVFDPKADTMETCGKIREKRFNQKVFIYEPFSLKTHRFNPFAYVDFGNDVVLTEDILSQI
DTRLKGHGMVASGGDFSTQIFGLAKLVFPERPNEKDPFFSNQARNLFVINCNIYRDLMWTKKGLEFVKRKKIIMPETPTM
FFIGSMASGINLIDEDTNMEKVVSLMEFFGGEEDKSGDNLRALSPATRNMWNNFKTMGGARETYSSVQGVYTSAFAPYNN
AMIRNFTSANDFDFRRLRIDEVSIGVIANPKESTIVGPILELFFNVMIYSNLILPIHDPQCKRSCLMLMDEFTLCGYLET
FVKAVGIMAEYNMRPAFVFQSKAQLENDPPLGYGRNGAKTILDNLSLNMYYGINNDNYYEHFEKLSKVLGKYTRQDVSRS
IDDNTGKTNTSISNKERFLMTPDELMTMGDELIILENTLKPIKCHKALYYDDPFFTDELIKVSPSLSKKYKLGKVPNQAT
FYDDLQAAKTKGELSYDKSLVPVGSSEL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cag5 AAR03947.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13885.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13776.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005779066.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03858.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13912.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD14023.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 BAD13803.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_005774545.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 AAR03887.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13830.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
cag5 YP_003728740.1 cag pathogenicity island protein beta Virulence cag PAI Protein 0.0 99
cag5 AAR03916.1 Cag5 Virulence cag PAI Protein 0.0 99
HP0524 BAD13967.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
virD4 NP_223191.1 cag island protein, DNA transfer protein Virulence cag PAI Protein 0.0 99
cag-beta AAF80195.1 Cag-beta Virulence cag PAI Protein 0.0 99
HP0524 BAD13995.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 99
HP0524 NP_207320.1 cag pathogenicity island protein (cag5) Virulence cag PAI Protein 0.0 99
HP0524 BAD13940.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD14049.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005777268.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
HP0524 BAD13857.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98
cag5 YP_005775727.1 cag pathogenicity island protein Virulence cag PAI Protein 0.0 98

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPB14_04055 YP_006219526.1 CAG pathogenicity island protein 5 VFG0284 Protein 0.0 99