Gene Information

Name : ureB (HPB14_00355)
Accession : YP_006218811.1
Strain : Helicobacter pylori HUP-B14
Genome accession: NC_017733
Putative virulence/resistance : Virulence
Product : urease subunit beta
Function : -
COG functional category : -
COG ID : -
EC number : 3.5.1.5
Position : 69767 - 71476 bp
Length : 1710 bp
Strand : -
Note : COG0804 Urea amidohydrolase (urease) alpha subunit

DNA sequence :
ATGAAAAAGATTAGCAGAAAAGAATATGTTTCTATGTATGGCCCTACTACAGGCGATAAAGTGAGATTGGGTGATACAGA
CTTGATCGCTGAAGTAGAACATGACTACACCATTTATGGCGAAGAGCTTAAATTCGGTGGCGGTAAAACCCTAAGAGAAG
GCATGAGCCAATCTAACAACCCTAGCAAAGAAGAACTGGATCTAATCATCACTAACGCTTTAATCGTGGATTACACCGGT
ATTTATAAAGCGGATATTGGTATTAAAGATGGCAAAATCGCTGGCATTGGTAAAGGCGGTAACAAAGACATGCAAGATGG
CGTTAAAAACAATCTTAGCGTGGGTCCTGCTACTGAAGCCTTAGCCGGTGAAGGTTTGATCGTAACTGCTGGTGGTATTG
ACACACACATCCACTTCATTTCACCCCAACAAATCCCTACAGCTTTTGCAAGCGGTGTAACAACCATGATTGGTGGCGGA
ACCGGTCCTGCTGATGGCACTAATGCGACTACTATCACTCCAGGCAGAAGAAATTTAAAATGGATGCTCAGAGCGGCTGA
AGAATATTCTATGAATTTAGGTTTCTTGGCTAAAGGTAACGCTTCTAACGATGCGAGCTTAGCCGATCAAATTGAAGCCG
GTGCGATTGGCTTTAAAATCCACGAAGACTGGGGCACCACTCCTTCTGCAATCAATCATGCGTTAGATGTTGCGGACAAA
TACGATGTGCAAGTCGCTATCCACACAGACACTTTGAATGAAGCTGGTTGTGTAGAAGACACTATGGCAGCTATTGCTGG
GCGCACTATGCACACTTTCCACACTGAAGGCGCTGGCGGCGGACACGCTCCTGATATTATTAAAGTGGCCGGTGAACACA
ACATTCTACCCGCTTCCACTAACCCCACTATCCCTTTCACTGTGAATACAGAAGCAGAACACATGGACATGCTCATGGTG
TGCCACCACTTGGATAAAAGCATTAAAGAAGATGTCCAGTTCGCTGATTCAAGGATCCGCCCTCAAACCATTGCGGCTGA
AGACACTTTGCATGACATGGGGATTTTCTCAATCACTAGTTCTGACTCTCAAGCGATGGGTCGTGTGGGTGAAGTTATCA
CCAGAACTTGGCAAACAGCTGACAAAAACAAAAAAGAATTTGGCCGCTTGAAAGAAGAAAAAGGCGATAACGACAACTTC
AGGATCAAACGCTACTTGTCTAAATACACCATTAACCCAGCGATCGCTCATGGGATTAGCGAGTATGTAGGTTCTGTAGA
AGTGGGCAAAGTGGCTGACTTGGTATTGTGGAGTCCCGCATTCTTTGGCGTGAAACCCAACATGATCATCAAAGGCGGAT
TCATTGCGTTAAGCCAAATGGGCGATGCGAACGCTTCTATCCCTACCCCACAACCGGTTTATTACAGAGAAATGTTCGCT
CATCATGGTAAAGCCAAATACGATGCAAACATCACTTTTGTGTCTCAAGTGGCTTATGACAAAGGCATTAAAGAAGAATT
AGGGCTTGAAAGACAAGTGTTGCCGGTAAAAAATTGCAGAAATATCACTAAAAAAGACATGCAATTCAACGACACTACCG
CTCACATTGAAGTCAATCCTGAAACTTACCATGTGTTCGTGGATGGCAAAGAAGTAACTTCTAAACCAGCCAATAAAGTG
AGCTTGGCGCAACTCTTTAGCATTTTCTAG

Protein sequence :
MKKISRKEYVSMYGPTTGDKVRLGDTDLIAEVEHDYTIYGEELKFGGGKTLREGMSQSNNPSKEELDLIITNALIVDYTG
IYKADIGIKDGKIAGIGKGGNKDMQDGVKNNLSVGPATEALAGEGLIVTAGGIDTHIHFISPQQIPTAFASGVTTMIGGG
TGPADGTNATTITPGRRNLKWMLRAAEEYSMNLGFLAKGNASNDASLADQIEAGAIGFKIHEDWGTTPSAINHALDVADK
YDVQVAIHTDTLNEAGCVEDTMAAIAGRTMHTFHTEGAGGGHAPDIIKVAGEHNILPASTNPTIPFTVNTEAEHMDMLMV
CHHLDKSIKEDVQFADSRIRPQTIAAEDTLHDMGIFSITSSDSQAMGRVGEVITRTWQTADKNKKEFGRLKEEKGDNDNF
RIKRYLSKYTINPAIAHGISEYVGSVEVGKVADLVLWSPAFFGVKPNMIIKGGFIALSQMGDANASIPTPQPVYYREMFA
HHGKAKYDANITFVSQVAYDKGIKEELGLERQVLPVKNCRNITKKDMQFNDTTAHIEVNPETYHVFVDGKEVTSKPANKV
SLAQLFSIF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ureC NP_286680.1 urease subunit alpha Virulence TAI Protein 8e-157 61
ureC NP_287088.1 urease subunit alpha Not tested TAI Protein 8e-157 61
ureC YP_005684266.1 Urease alpha subunit Not tested PiCp 7 Protein 6e-146 59
ureC YP_005682174.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-146 59
ureC YP_003784325.1 urease subunit alpha Not tested PiCp 7 Protein 8e-146 59
ureC YP_005686358.1 Urease alpha subunit Not tested PiCp 7 Protein 8e-146 59

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ureB YP_006218811.1 urease subunit beta VFG0270 Protein 0.0 99