Gene Information

Name : HPB14_00520 (HPB14_00520)
Accession : YP_006218842.1
Strain : Helicobacter pylori HUP-B14
Genome accession: NC_017733
Putative virulence/resistance : Resistance
Product : cystathionine gamma-synthase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.8
Position : 106290 - 107432 bp
Length : 1143 bp
Strand : -
Note : COG0626 Cystathionine beta-lyases/cystathionine gamma-synthases

DNA sequence :
ATGCACATGCAAACCAAATTAATCCATGGGGGCATTAGTGAAGACACGACAACGGGGGCGGTGAGCGTGCCTATTTATCA
AACTTCCACCTACCGCCAAGACGCCATAGGCCACCATAAAGGCTATGAATACTCTCGCTCAGGCAACCCCACGCGCTTTG
CTTTAGAAGAACTCATCGCTGATTTAGAGGGGGGGGTTAAGGGGTTTGCTTTTGCCTCTGGCCTAGCTGGAATCCACGCC
GTTTTTTCCCTCTTGCAATCAGGCGATCATGTGTTATTGGGCGATGATGTTTATGGGGGGACTTTCCGCTTGTTTAATAA
AGTGCTTGTCAAAAACGGGCTTTCTTGCACCATTATAGACACTAGCGATATATCCCAAATCAAAAAGGCTATCAAACCCA
ACACCAAAGCCCTTTATTTAGAAACCCCTAGTAACCCCTTGCTTAAAATCACGGATTTAGCGCAATGCGCTAGTGTCGCT
AAAGATCATAATTTGCTCACTATCGTGGATAACACCTTTGCCACCCCCTATTATCAAAACCCGCTTCTTTTGGGAGCGGA
TATTGTGGTGCATAGCGGCACAAAATACTTAGGCGGTCATAGCGATGTGGTCGCTGGGCTTGTAACCACCAATAATGAAG
CGTTAGCCCAAGAGATCGCTTTTTTCCAAAACGCTATCGGTGGGGTTTTAGGCCCTCAAGACAGTTGGCTGTTGCAAAGA
GGGATTAAAACGCTGGGATTACGCATGCAAGCCCATCAAAAAAACGCCCTTTGCGTGGCTGAATTTTTAGAAAAACACCC
TAAAGTGGAAAGGGTTTATTACCCGGGCCTACCCACCCACCCTAATTACGAGCTAGCCAAAGCCCAAATGCGTGGCTTTA
GCGGGATGCTCTCTTTCACTCTCAAAAATGACAGCGAGGCGGCTCTTTTTGTAGAAAGCCTTAAATTATTCATTTTAGGC
GAGAGTTTGGGCGGGGTGGAAAGCTTGGTGGGGATTCCAGCGTTTATGACCCATGCGTGTATCCCTAAAGAACAACGAGA
AGCCGCAGGGATTAGAGATGGCTTGGTGCGCTTGTCTGTAGGGATTGAGCATGAACAGGATTTGTTAGAAGATTTAGAGC
AAGCGTTCGCTAAAATAGGCTAA

Protein sequence :
MHMQTKLIHGGISEDTTTGAVSVPIYQTSTYRQDAIGHHKGYEYSRSGNPTRFALEELIADLEGGVKGFAFASGLAGIHA
VFSLLQSGDHVLLGDDVYGGTFRLFNKVLVKNGLSCTIIDTSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVA
KDHNLLTIVDNTFATPYYQNPLLLGADIVVHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQR
GIKTLGLRMQAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKAQMRGFSGMLSFTLKNDSEAALFVESLKLFILG
ESLGGVESLVGIPAFMTHACIPKEQREAAGIRDGLVRLSVGIEHEQDLLEDLEQAFAKIG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-97 54
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 7e-99 54
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-71 47

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
HPB14_00520 YP_006218842.1 cystathionine gamma-synthase BAC0207 Protein 3e-63 44