Gene Information

Name : S70_12655 (S70_12655)
Accession : YP_006217065.1
Strain : Providencia stuartii MRSN 2154
Genome accession: NC_017731
Putative virulence/resistance : Virulence
Product : superfamily I DNA helicase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2713598 - 2717107 bp
Length : 3510 bp
Strand : -
Note : COG1112 Superfamily I DNA and RNA helicases and helicase subunits

DNA sequence :
ATGGATGATAACTATCTAAAATTAGCCGCTTATTGGCGAAATTCACTAGCTGATGCGGAGTCAGGAAAAGGGGCTCTAGA
AAAACGAGACACGAATAATTTGATTAAATGGGAAAGTGTTTCATCAGGTCGCCTTGATAGCATTATTACTGAGCGTTTTT
TTTCCGATGAAAAAGATGATGTAAACACAGTAGATGTCATTTTACGCCCAAAAGTTTTTATACGGCTAATACAACATGGA
AAAGAACGCCTTGCTGGCAGTCCAACATATGTCACCCCGCTTGTGACACTAGCAAAAATAAATCGAGAAGGTTTTTTATT
TCCAACATCAACTACCGTCATTCCTAGAGATCTACTTGAACCGCTGTCTCATGGTTCATTCTCTATTGGTGAAATATCTG
AGTACGATAAATATAAAACGACGAATACATCATCATCTATGCATTATGATGAATCTCATTTAGAAACTGAAGAAACTGAA
GAAGAAAAAGAGAAAAGATATGAAGGCTATTTCCAAGGGTGGGGGTCATATTTAGATGATTCATATAAACTATTAAATAG
TATCGCTGAATCTTGGATAAACACTCACGAACAGTATGAACTTGCCGATTACGGATATATACTAAAAAAAGTAGAACCTA
AAGGTGCTAGTACTCATATTCTTTCTCTTTATGACCACTTACTTGTAAATAAGAAAAAAGTCCCATTATTTGAGCGGTTC
GCTAACTTCACTTCTCCTGAAATCGAGCCACTAATTTCAACTGAAGATTCCTTTGTTTATCGATTAGGTCATTCTGGGGA
TAGGTTTCCTTTAGCGCTGGCTCAGCGAGATGCACTAGGTCATTTTCTTAATGCCAATGACGGCGATATTTTAGCAGTCA
ACGGCCCTCCTGGCACAGGAAAAACGACTTTACTTTTATCCATTATTGCAACGCTTTGGGCTAAAGCCGCGCTCGAACAA
ACAAATCCGCCAATTGTACTTGCGACTTCAACCAATAACCAAGCCGTCACTAATATCATCGAAGCATTTGGAAAGGACTT
TTCCGAAGGAAATGGCGCTATGTCAGGTCGCTGGCTGCCAAATATTAAAAGTTTTGGTGCTTATTTCCCTTCAAGTACCA
AGAAAGCAGAAGCAATCAAAAAGTACCAGACTGACGAGTTTTTTAAAGAAATAGAATCTAAAGAATATATTGAAAGCGCA
CTAGATTTTTATTTAAATAAAGCCAAATTGGCATTCCCCAATAAAGATTGTTCATCCCCTGAAAAAATTATTGCGTTATT
GCATGAACAACTCTCCGAGCAGTCCAATAAGTTAGTTGAGATAAAGCAAACTTGGGATTCTCTACAAGAAATTCGAGGGA
AAATCGCCCAAGTATCCGATGATATAAATTCTTATCTTAATGACCAGACCGTATTACTATCAAAAACACAATCTAAAATA
GATAGGTTAAAAATTGCTTCAGTAGAATGGGATAAATATAGAGCGAATGAATCTCTATTTATTTCATTATTTTCATGGCT
TCCACCAGTCGGAAAAAAGCGTTACTACCAAGTTAAGCTGTTCCTTGCTGATAAATTAGATGGCTTCGACATTGAAAAAG
AACCAACTGAAATCAATGTTATTGATAGTTTAATTAAAAAATTGCTCGATAGTGAAGAGCGAAAACAAGAGGATTATCAA
CAACAAATTAATTATATACATCAAATAACCCAACAAGAAAAAGAGATATTGGCAAAGTGGCTCACCATTGCTTCTGAACT
TGGATATAAACAGGGTGAAGAACCAAACTTGTTGCAAATTGATGAACTGGCTGACACACAAATCAGATTTCCTCTATTTT
TGCTAACCACTCATTATTGGGAAGGCCGTTGGCTCATTGATGTACTCAATATTGATGATCTTAACAAGGAGAAAGGAAAA
AACGGGCTTAAAACAGTAGAACGTCACTGGCAACGTAAAATGATGTTAACGCCATGTGTGGTAATGACTTGCTATATGTT
ACCTAACTATATGCTTTTACCCGCAAATAAAGGGCAAAAAAAGCATGAAAGAGGCTATGCATATAATATTGCTGATTTAC
TCATTGTCGATGAGGCCGGTCAAGTACTACCTGAAGTTGCTGCGGCCTCCTTCGCATTTGCTAAAAAAGCACTTGTTATT
GGCGATACTGCACAAATACCTCCAATATGGAATATCACTCGAGCCATTGACTCCGGAAACATGTTGGAAGAAAAAATTCT
GAGCGAAAATACACAAGAACAAATCAATGCAGAATATGACTCAATCACCGAACTCGGAAAGTGTTCAGCTTCTGGCAGTG
TAATGAAAATTGCACAATTGTCTTCACGCTACCATTATGACTCTGATTTAGAGAGAGGTATGTATCTTTACGAGCATCGA
CGCTGCTTTGATAACATCATCGGGTACTGTAATGAGCTTTGCTATCAAGGAAAATTACTACCAAAAAGAGGAGATAGTGA
CAACCTTTTATTCCCTGCAATGGGCTATCTCCATATCGATGGAAAAGGTGAGCAAAGAAATACAGGAAGCCGTTTCAATC
GATTAGAAGCAGAAATCATTTCAGCTTGGTTAATAGAAAATCGACAACGTATCGAAAATCACTATGGGAAACCTATTCAG
CAAATAGTTGGAATAGTAACGCCATTCAGTGCTCAAGTTTCAATTATTAAAGATGCTCTTAGTAAACAAGGAATTACTGC
TGAAACTAGTGAAAATACACTAACTGTCGGTACTGTTCACTCACTTCAAGGCGCAGAAAGAGCGATTGTTATATTTTCCC
CTGTATATTCAAAACATGAAGATGGCGGTTTTATCGATAGTGATAACAGCATGCTGAATGTTGCTGTATCACGCGCTAAG
GATAGTTTTCTTGTTTTTGGAGATATGGATTTATTTGAAATCCAACCCCCTTCTTCACCAAGGGGATTGCTTGCCAAATA
CTTATTCTTAGAGGAAAGGAATGCCTTACATTTCGAATACAAAGAAAGGCAAGACTTACAAAAATCGAATACTCAAATAT
ACACGCTTCACGGTGTGAAAGAGCACGATGACTTTTTAAATCAAACAATTAGTAACACTGAAAAACATATTACCATTATA
TCCCCTTGGTTAAATTTGCAAAAACTTGAACAAGCTGGATTCATTGATTCCATGGCTCAAGCAACAGCTAAGGGTATCCA
AGTAAAAGTGATCACCGATAGAAATTACAATATCCAACACTCTGATCCTGAAAAACGTAAAGAAAGAGAAGTCAATCTTC
ATAATGCCTTGGAACAATTAGATTCTTATGGCATTGCTACAAAGCTAGTGCGACGAGTTCATAGTAAAATTGTTATCGGA
GATGATAATTTACTCTGCATTGGCTCATTCAATTGGTTTAGCGCATCTCGTGAAGCCAAGTATGAACGATATGATACCTC
TATGGTTTATTGTGGTGGAAGTTTGAAAGAAGAAATTCAAGCTATCCACAACAACCTTGAACGACGGTAA

Protein sequence :
MDDNYLKLAAYWRNSLADAESGKGALEKRDTNNLIKWESVSSGRLDSIITERFFSDEKDDVNTVDVILRPKVFIRLIQHG
KERLAGSPTYVTPLVTLAKINREGFLFPTSTTVIPRDLLEPLSHGSFSIGEISEYDKYKTTNTSSSMHYDESHLETEETE
EEKEKRYEGYFQGWGSYLDDSYKLLNSIAESWINTHEQYELADYGYILKKVEPKGASTHILSLYDHLLVNKKKVPLFERF
ANFTSPEIEPLISTEDSFVYRLGHSGDRFPLALAQRDALGHFLNANDGDILAVNGPPGTGKTTLLLSIIATLWAKAALEQ
TNPPIVLATSTNNQAVTNIIEAFGKDFSEGNGAMSGRWLPNIKSFGAYFPSSTKKAEAIKKYQTDEFFKEIESKEYIESA
LDFYLNKAKLAFPNKDCSSPEKIIALLHEQLSEQSNKLVEIKQTWDSLQEIRGKIAQVSDDINSYLNDQTVLLSKTQSKI
DRLKIASVEWDKYRANESLFISLFSWLPPVGKKRYYQVKLFLADKLDGFDIEKEPTEINVIDSLIKKLLDSEERKQEDYQ
QQINYIHQITQQEKEILAKWLTIASELGYKQGEEPNLLQIDELADTQIRFPLFLLTTHYWEGRWLIDVLNIDDLNKEKGK
NGLKTVERHWQRKMMLTPCVVMTCYMLPNYMLLPANKGQKKHERGYAYNIADLLIVDEAGQVLPEVAAASFAFAKKALVI
GDTAQIPPIWNITRAIDSGNMLEEKILSENTQEQINAEYDSITELGKCSASGSVMKIAQLSSRYHYDSDLERGMYLYEHR
RCFDNIIGYCNELCYQGKLLPKRGDSDNLLFPAMGYLHIDGKGEQRNTGSRFNRLEAEIISAWLIENRQRIENHYGKPIQ
QIVGIVTPFSAQVSIIKDALSKQGITAETSENTLTVGTVHSLQGAERAIVIFSPVYSKHEDGGFIDSDNSMLNVAVSRAK
DSFLVFGDMDLFEIQPPSSPRGLLAKYLFLEERNALHFEYKERQDLQKSNTQIYTLHGVKEHDDFLNQTISNTEKHITII
SPWLNLQKLEQAGFIDSMAQATAKGIQVKVITDRNYNIQHSDPEKRKEREVNLHNALEQLDSYGIATKLVRRVHSKIVIG
DDNLLCIGSFNWFSASREAKYERYDTSMVYCGGSLKEEIQAIHNNLERR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF_2 AAZ04413.1 superfamily I DNA helicase Not tested PAI I APEC-O1 Protein 0.0 67
APECO1_3532 YP_854230.1 superfamily I DNA helicase Not tested PAI I APEC-O1 Protein 0.0 67
S3169 NP_838460.1 superfamily I DNA helicase Not tested SHI-1 Protein 0.0 66
SF2965 NP_708739.1 superfamily I DNA helicase Not tested SHI-1 Protein 0.0 66
unnamed CAD42018.1 hypothetical protein Not tested PAI II 536 Protein 0.0 66

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
S70_12655 YP_006217065.1 superfamily I DNA helicase VFG0627 Protein 0.0 66
S70_12655 YP_006217065.1 superfamily I DNA helicase VFG1537 Protein 0.0 66