Gene Information

Name : lysS (B2K_35835)
Accession : YP_006193781.1
Strain : Paenibacillus mucilaginosus K02
Genome accession: NC_017672
Putative virulence/resistance : Virulence
Product : lysyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : 6.1.1.6
Position : 8418607 - 8420103 bp
Length : 1497 bp
Strand : -
Note : class II; LysRS2; catalyzes a two-step reaction, first charging a lysine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA; in Methanosarcina barkeri, LysRS2 charges both tRNA

DNA sequence :
ATGAGTGTTGAACTGGAATTGAACGAACTGCTTCAAATTCGACGCGGCAAGCTGGACGAGCTGAGATCTATGGGAATCGA
TCCGTTCGGTCAAAAGTACGAAAGAACGCACCACGCCGCCGAGATTACCAAGGCCTATGAAGAGAAGTCCAAAGAAGAAC
TGGACGAGCTCAAGGCAGAGGTCAGCATTGCCGGCCGGATTATGCAGAAGCGGGAGATGGGGAAGGCCGGATTTGCCCAC
CTGCAGGACATTACAGGTAAGATCCAGATCTATGTGCGTGCGGACGCTGTAGGGGAGACGCCTTACAAAGCCTATGACCT
GCTCGACATCGGGGATATTATCGGTATTCGGGGAACGGTATTCAAGACGAAGACGGGAGAGCTTTCCGTGAAGGCCTCTT
CTGTCGTCGTTCTTTCCAAATCGCTGCTTCCTCTGCCGGAGAAGTACCATGGCTTGAAGGACGTGGAGCTTCGTTACCGC
CAGCGCTACGTTGACCTGATTATGAATCAGGATGTTCAGCAGACGTTCATCGCCCGTTCGAAGATCATTCAATCGATGCG
CCGCTACCTGGATGCCCTAGGCTATCTTGAGGTGGAGACGCCGACTCTGCATGCGATTGCCGGCGGTGCTGCCGCCCGTC
CGTTCATTACGCATCATAATGCGCTGGATATGCAGTTGTATATGCGTATTGCCATCGAGCTGCACCTGAAGCGCCTGATT
GTCGGTGGCATGGAGAAGGTGTATGAAATCGGCCGTGTTTACCGTAATGAGGGAATTTCCACGCGTCACAATCCGGAATT
CACGATGATTGAGCTGTATGAGGCGTATGCCGATTATAAGGATATCATGAAGCTGACGGAGGAAATGATCGCGCATATCG
CTCAGGAAGTGCTCGGCACTACAACGATTATGTACCAGGGCCATGAGGTCAACCTGGCTCCACAGTGGCGCCGTGTGACG
ATGGTCGATGCGATCAAGGAAGTGGTAGGCGTTGATTTCAGCGTGCAGATGAGCGACGAGGAAGCACACCGTCTGGCCAA
AGAGCATAAGGTTCCTGTAGAGCCTACCATGACCTTCGGCCATATTGTGAACCAGTTCTTCGAGACGTTCGTCGAGGAGA
CACTGATTCAGCCGACGTTCATCACGGGTCATCCGGTGGCAATCTCACCATTGGCCAAAAAGAGTGACGCCGATCCGCGT
TTCACGGACCGCTTCGAGCTCTTTATCGTGGCGCGTGAGCATGCGAATGCCTTCACGGAGCTGAACGATCCGATCGACCA
GCGGGAGCGTTTTGCCGCGCAGCTTGTGGAACGCGAGCAGGGCAATGACGAGGCGCATGAGATGGATGAAGATTTCGTCC
GTGCCCTGGAATACGGTATGCCGCCTACAGGCGGGCTTGGCATCGGCATCGACCGGCTGGTCATGCTGCTTACAGATGCC
CCGTCGATTCGCGACGTACTGCTCTTCCCTCTGATGCGTGAGCGTCAGGGAGAATAA

Protein sequence :
MSVELELNELLQIRRGKLDELRSMGIDPFGQKYERTHHAAEITKAYEEKSKEELDELKAEVSIAGRIMQKREMGKAGFAH
LQDITGKIQIYVRADAVGETPYKAYDLLDIGDIIGIRGTVFKTKTGELSVKASSVVVLSKSLLPLPEKYHGLKDVELRYR
QRYVDLIMNQDVQQTFIARSKIIQSMRRYLDALGYLEVETPTLHAIAGGAAARPFITHHNALDMQLYMRIAIELHLKRLI
VGGMEKVYEIGRVYRNEGISTRHNPEFTMIELYEAYADYKDIMKLTEEMIAHIAQEVLGTTTIMYQGHEVNLAPQWRRVT
MVDAIKEVVGVDFSVQMSDEEAHRLAKEHKVPVEPTMTFGHIVNQFFETFVEETLIQPTFITGHPVAISPLAKKSDADPR
FTDRFELFIVAREHANAFTELNDPIDQRERFAAQLVEREQGNDEAHEMDEDFVRALEYGMPPTGGLGIGIDRLVMLLTDA
PSIRDVLLFPLMRERQGE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD66193.1 putative lysil-tRNA synthetase LysU Not tested PAI III 536 Protein 2e-105 51

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lysS YP_006193781.1 lysyl-tRNA synthetase VFG1668 Protein 1e-105 51