Gene Information

Name : mccB (HBHAL_2023)
Accession : YP_006179660.1
Strain : Halobacillus halophilus DSM 2266
Genome accession: NC_017668
Putative virulence/resistance : Resistance
Product : cystathionine gamma-lyase / homocysteine gamma-lyase
Function : -
COG functional category : -
COG ID : -
EC number : 4.4.1.1
Position : 1031638 - 1032774 bp
Length : 1137 bp
Strand : +
Note : -

DNA sequence :
ATGAGAAAGAAAACACAATTAATTCATGGTGGTATTACAGGAGATGAAAAAACCGGTGCAGTTTCTGTACCCATTTATCA
GGTTAGTACTTATGCACAGGACGGGGTAGGAAAGCATCGGGGATATGAGTATTCCAGAACCGGCAACCCAACTCGTTTTG
CTCTTGAAGAATTAATTAAAGAAATTGAAGGCGGTTATGCCGGTTTTGCTTTTGGGTCTGGAATGGCTGCGATTACCGCT
GTCCTCATGACCTTTAAACAGGGAGATCATATTATTTTTACGGATGATGTGTACGGCGGAACATACCGCCTCGTTTCCCA
GGTGATCACCCGCTTTGGTCTCAAAGCAAGCTTTGTAGATACTAGTGATTCCAAAAACATTGAAGCAGCGATGACCGAGC
GCACGAAAGCGTTATATGTTGAGACGCCGACGAATCCTTTGTTAAAAATAACGGATCTTAAGAAAACTTCTGAGCTTGCT
AAAACTCATAATTTAACCTTCATCGTGGATAATACATTCAGCACGCCTTACTGGCAGAACCCAATTGATTTCGGAGCAGA
CATCGTTCTTCACAGTGCAACGAAATACCTGGGCGGACATAGTGACGTAGTCGCCGGACTGGTTGTTGTGAACTCTGAAC
AATTAGCTGAAGAGGTTCATTTCGTACTAAACTCCTCTGGTGGTATTCTCGGACCGCAGGATGCCTGGCTACTTATGCGC
GGTATTAAAACATTAGGTGTCCGTATGGAAGAAATTGAAGAAAACACGCGGGGCTTCGTTGAGTTTTTACAAGGACTTCC
AGAGGTGACGAACATTTACTATCCAGGTCTTACAGAGCACGTGGGTCATGATGTTCATCAGAATCAGGCACGCGGAAACG
GCGGAATGATCTCTTTTGACGTAGGAAGCGGGGAAAAAGCAGATAAAGTGCTGCAGAATGTCCGCTACTTCACCCTTGCT
GAAAGTCTTGGAGCAGTGGAAAGCTTAATTTCTGTCCCGGCTAAAATGACACATGCTTCTATTCCGGAAGTGCGCCGGGG
TGAGCTTGGTATAACCGACGGGCTTGTCCGTGTATCCATCGGACTTGAAGATATTGAAGATTTGAAAGAAGATTTTCTTG
AGGCTTTACGTAAATAA

Protein sequence :
MRKKTQLIHGGITGDEKTGAVSVPIYQVSTYAQDGVGKHRGYEYSRTGNPTRFALEELIKEIEGGYAGFAFGSGMAAITA
VLMTFKQGDHIIFTDDVYGGTYRLVSQVITRFGLKASFVDTSDSKNIEAAMTERTKALYVETPTNPLLKITDLKKTSELA
KTHNLTFIVDNTFSTPYWQNPIDFGADIVLHSATKYLGGHSDVVAGLVVVNSEQLAEEVHFVLNSSGGILGPQDAWLLMR
GIKTLGVRMEEIEENTRGFVEFLQGLPEVTNIYYPGLTEHVGHDVHQNQARGNGGMISFDVGSGEKADKVLQNVRYFTLA
ESLGAVESLISVPAKMTHASIPEVRRGELGITDGLVRVSIGLEDIEDLKEDFLEALRK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 1e-105 59
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-107 59
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 2e-70 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mccB YP_006179660.1 cystathionine gamma-lyase / homocysteine gamma-lyase BAC0207 Protein 4e-63 41