Gene Information

Name : WFL_22655 (WFL_22655)
Accession : YP_006175953.1
Strain : Escherichia coli W
Genome accession: NC_017664
Putative virulence/resistance : Unknown
Product : site-specific recombinase, phage integrase family protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4774006 - 4775271 bp
Length : 1266 bp
Strand : +
Note : COG0582 Integrase

DNA sequence :
ATGGCTCTGAGTGATGTGAAGGTCCGTTCGGCTAAGCCGGAAGCAAAAGCCTATAAACTTACTGACGGTGAAGGCATGGT
TTTGTTGGTTCACCCTAATGGCTCCAAATACTGGCGACTTCGTTATCGTTTTGGCGGTAAGGAGAAGATGCTGGCGCTGG
GGAAATACCCTGAAGTCTCGCTGGTCGATGCCAGAGGTCGCCGGGATGAAGCCCGTAAGTTGTTAGCTAACGGCGTCGAT
CCTAGTGAGAACAAGAAAGCTGTTAAGGTAGAGCATGAGCAAGAGGTGATAACATTTGAAGTGGTAGCCAGAGAGTGGCA
CGCCAGCAATCAGAAGTGGTCTGCATCGCATAGCGCTCGTGTATTGAAAAGCCTCGAAGATAATCTCTTTGCTGCTATCG
GTAAGCGGAACATTGCTGATCTGAAGACTCGGGATCTGCTTGTCCCCATCAAAGCGGTGGAGTCGTCTGGGCGTCTCGAA
GTCGCTGCTCGTTTGCAGCAGCATACTACCGCGATTATACGCTTTGCTGTACAGAGTGGATTAATCGACTACAACCCCGC
TCAAGAGATTGCTGGTGCGGTTGCTACGGCGAAAAGACAGCATCGTGCTGCTCTGGAACTTAACCGCATTCCTGAATTGC
TTCAACGCATCTATCACTATTCTGGCAGGCCGTTAACCCGACTGGCGGTTGAACTCACATTGTTAGTTTTCATCCGTTCA
AGCGAGTTGCGTTTTGCTCGCTGGTCAGAAGTTGATTTTGATACTGCCATGTGGACGATTCCGGGAGAACGTGAGCCACT
GGAGGGAGTTAAGCATTCTCAGCGTGGTTCGAAGATGCGGACTCCACATCTTGTACCCTTATCTCGACAAGCTCTCACCA
TTCTGGAAAAAATCAAAAGCATGAGTGGAAACCGTGAGCTGATCTTCGTTGGTGATCACGATCCGCGTAAGCCAATGAGT
GAGAATACGCTTAACAAGGCCTTGCGAGTGATGGGCTATGACACGAAAACGGAAGTGTGTGGACATGGTTTCAGGACGAT
GGCGTGTAGTTCTTTGATTGAATCGGGATTGTGGTCGAGGGATGCAGTAGAGCGGCAGATGAGTCATCAGGAACGTAGCT
CAGTACGGGCGGCTTATATCCATAAGGCGGAACATCTTGGGGAGCGAATGTTGATGCTGCAGTGGTGGGCTGATTATCTG
GATGCGAATAGAATGGCGGCTATCACTCCATTTGACTATGCAAAGATTAATAGTTCTTTTCGATAA

Protein sequence :
MALSDVKVRSAKPEAKAYKLTDGEGMVLLVHPNGSKYWRLRYRFGGKEKMLALGKYPEVSLVDARGRRDEARKLLANGVD
PSENKKAVKVEHEQEVITFEVVAREWHASNQKWSASHSARVLKSLEDNLFAAIGKRNIADLKTRDLLVPIKAVESSGRLE
VAARLQQHTTAIIRFAVQSGLIDYNPAQEIAGAVATAKRQHRAALELNRIPELLQRIYHYSGRPLTRLAVELTLLVFIRS
SELRFARWSEVDFDTAMWTIPGEREPLEGVKHSQRGSKMRTPHLVPLSRQALTILEKIKSMSGNRELIFVGDHDPRKPMS
ENTLNKALRVMGYDTKTEVCGHGFRTMACSSLIESGLWSRDAVERQMSHQERSSVRAAYIHKAEHLGERMLMLQWWADYL
DANRMAAITPFDYAKINSSFR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 1e-150 77
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 3e-148 69
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 1e-145 69
int AAK16198.1 Int Not tested PAI-I AL862 Protein 4e-147 69
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 4e-147 69
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 1e-147 69
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 2e-145 68
int AAK00456.1 Int Not tested SHI-1 Protein 4e-138 68
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 6e-148 68
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 4e-148 68
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 8e-148 68
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 8e-148 68
int AAL51028.1 CP4-like integrase Not tested LEE Protein 4e-147 68
int CAC81896.1 integrase Not tested LEE II Protein 2e-137 68
int-phe AAL60261.1 Int-phe Not tested LEE Protein 4e-147 68
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 8e-147 68
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 2e-146 68
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 7e-147 68
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 5e-147 68
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 5e-147 68
int AAL51003.1 CP4-like integrase Not tested LEE Protein 4e-147 68
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 4e-147 68
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 8e-129 62
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 8e-129 62
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 2e-82 57
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 5e-119 57
int YP_002346908.1 integrase Not tested HPI Protein 1e-110 55
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 1e-110 55
int2 NP_993013.1 integrase Not tested HPI Protein 1e-110 55
int CAA08754.1 integrase Not tested HPI Protein 3e-111 55
int CAA21384.1 - Not tested HPI Protein 1e-110 55
int CAB59974.1 integrase Not tested HPI Protein 6e-112 55
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 2e-93 55
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 2e-115 55
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 2e-115 55
unnamed AAD17660.1 unknown Not tested HPI Protein 9e-108 54
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 7e-105 52
int CAC39282.1 integrase Not tested LPA Protein 8e-86 43
int AAD44730.1 Int Not tested SHI-2 Protein 3e-85 43
aec33 AAW51716.1 Int Not tested AGI-3 Protein 8e-86 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 2e-74 42
ECs4534 NP_312561.1 integrase Not tested LEE Protein 5e-84 42
int AAC31482.1 CP4-like integrase Not tested LEE Protein 4e-84 42
int ACU09430.1 integrase Not tested LEE Protein 4e-84 42
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 5e-84 42
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 7e-84 42
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 9e-84 42
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 9e-84 42
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 2e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
WFL_22655 YP_006175953.1 site-specific recombinase, phage integrase family protein VFG1536 Protein 6e-151 77
WFL_22655 YP_006175953.1 site-specific recombinase, phage integrase family protein VFG1693 Protein 5e-148 69
WFL_22655 YP_006175953.1 site-specific recombinase, phage integrase family protein VFG0626 Protein 3e-148 68
WFL_22655 YP_006175953.1 site-specific recombinase, phage integrase family protein VFG0783 Protein 2e-84 42
WFL_22655 YP_006175953.1 site-specific recombinase, phage integrase family protein VFG0598 Protein 4e-84 42