Gene Information

Name : WFL_01270 (WFL_01270)
Accession : YP_006171709.1
Strain : Escherichia coli W
Genome accession: NC_017664
Putative virulence/resistance : Virulence
Product : FliI/YscN family ATPase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 290588 - 291925 bp
Length : 1338 bp
Strand : +
Note : COG1157 Flagellar biosynthesis/type III secretory pathway ATPase

DNA sequence :
GTGAGTGATTTTTCTGCGTTCGATAACGCCCTGCGCTCGCTGGAGTCGATCCCGCTGGCCCGCGTCGCCGGGCGGCTGGT
GCGCCTTAACGGCATCCTGCTGGAGAGTGTCGGCTGCCCGCTAATGACCGGGCAGCTGTGCCGCATCGAAAGTGCCAATC
ACACGCTGATCGACGCGCAGGCCGTGGGCTTTAATCGCGACATCACCTATTTAATGCCGTTTAAACAGCCGGTCGGCCTG
ATGGCAGGCGCACGCGTCTTCCCGGAAGAAAAAGCCCACGACATCCTGATAGGCGAAAGCTGGTTAGGCCGCGTGGTGAA
TGGCCTCGGCGAACCGCTGGATGGCAAAGGCCGCCTGAACGGCAACGACCTTCTGCCGCCGTTGCCGCCCTCGGTTAATC
CCTTAACTCGTCGTTCGGTAGACGAACCGCTGGACGTGGGCGTGAAAGCGATCAACGGCCTGCTGACCATCGGCAAAGGC
CAGCGCGTCGGACTAATGGCAGGCAGCGGCGTCGGGAAAAGCGTGCTGCTGGGGATGATCACCCGCCAGACCAAAGCCGA
TATCGTGGTGGTTGGGCTGATTGGGGAACGCGGGCGCGAAGTGAAAGAGTTTATCGACCACTCGCTGGGCGCGGACGGGC
TGGCAAAGTCTATCGTCGTCGTCGCGCCTGCCGATGAATCGCCGCTGATGCGTCTGAAAGCCACCGAACTGTGCCACTCC
ATCGCCGCCTGGTTTCGCGACCGCGGGCATCACGTCTTACTGCTGGTGGATTCCCTGACCCGCTACGCGATGGCGCAGCG
GGAAATCGCCCTCTCGCTCGGCGAACCGCCCGCCACCAAAGGTTATCCGCCATCGGCATTCGGCATGATCCCCAAACTGG
TCGAAAGCGCAGGCAACAGCGAAAGCGCGGGATCGATGACCGCCATCTACACCGTGCTGGCGGAAGGTGACGACCAGCAA
GATCCGATTGTCGACTGCGCGCGCGCGGTGCTGGACGGGCATATCGTATTAACCCGCAAACTGGCGGAAGCGGGGCACTA
TCCGGCCATTGATATCGGCCAGTCGATCAGCCGCTGCATGAACCAGGTCACCAGCCTGGAACATCAGCAATCCGCCCGCG
CGTTAAAGCAAAACTATGCCGCCTATATGGAGATCAAACCTCTGATCCCGCTCGGCGGCTATGTGGCAGGTGCCGACGCC
AGCGTCGACAAAGCGGTGAAAATGTTTCCGGCCATTGAGCGATTTTTGCGCCAGGAGATGCGCGAACCCGCCTCCCTCGA
ACTGGTGCAAAGCCGCCTGCAAATCCTCTTTCCTTGTGCCAAAAAGGCAGAACAGTAA

Protein sequence :
MSDFSAFDNALRSLESIPLARVAGRLVRLNGILLESVGCPLMTGQLCRIESANHTLIDAQAVGFNRDITYLMPFKQPVGL
MAGARVFPEEKAHDILIGESWLGRVVNGLGEPLDGKGRLNGNDLLPPLPPSVNPLTRRSVDEPLDVGVKAINGLLTIGKG
QRVGLMAGSGVGKSVLLGMITRQTKADIVVVGLIGERGREVKEFIDHSLGADGLAKSIVVVAPADESPLMRLKATELCHS
IAAWFRDRGHHVLLLVDSLTRYAMAQREIALSLGEPPATKGYPPSAFGMIPKLVESAGNSESAGSMTAIYTVLAEGDDQQ
DPIVDCARAVLDGHIVLTRKLAEAGHYPAIDIGQSISRCMNQVTSLEHQQSARALKQNYAAYMEIKPLIPLGGYVAGADA
SVDKAVKMFPAIERFLRQEMREPASLELVQSRLQILFPCAKKAEQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 3e-72 46
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 1e-74 46
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 7e-75 46
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 2e-73 46
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 7e-84 45
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 7e-84 45
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 4e-85 45
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 45
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 45
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-83 45
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-83 45
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 1e-83 45
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-84 45
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 3e-71 45
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 3e-71 45
lscN AAO18044.1 LscN Virulence TTSS locus Protein 4e-82 45
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 1e-79 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-67 44
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 7e-69 44
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 6e-69 44
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 3e-69 44
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 3e-72 44
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-72 43
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 8e-73 43
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-72 43
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-72 43
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 2e-72 43
escN CAI43874.1 EscN protein Virulence LEE Protein 2e-71 42
escN CAC81862.1 EscN protein Virulence LEE II Protein 5e-71 42
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-71 42
escN AAK26715.1 EscN Virulence LEE Protein 5e-71 42
escN AAL57542.1 EscN Virulence LEE Protein 5e-71 42
escN YP_003223475.1 translocator EscN Virulence LEE Protein 3e-71 42
unnamed AAL06369.1 EscN Virulence LEE Protein 7e-70 42
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-70 42
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 2e-70 42
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 2e-69 42
escN YP_003236088.1 translocator EscN Virulence LEE Protein 2e-70 41
escN NP_290268.1 hypothetical protein Virulence LEE Protein 6e-71 41
ECs4568 NP_312595.1 EscN Virulence LEE Protein 6e-71 41
escN AAC38383.1 EscN Virulence LEE Protein 5e-71 41
escN AAC31513.1 L0034 Virulence LEE Protein 4e-71 41
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 4e-71 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG1254 Protein 1e-108 56
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG2499 Protein 3e-102 54
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG2331 Protein 1e-99 52
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG0192 Protein 3e-83 44
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG0390 Protein 5e-79 44
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG0048 Protein 2e-85 43
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG0515 Protein 5e-73 43
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG2144 Protein 3e-80 41
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG0812 Protein 2e-71 41
WFL_01270 YP_006171709.1 FliI/YscN family ATPase VFG0730 Protein 3e-71 41