Gene Information

Name : yfcU (WFL_12375)
Accession : YP_006173920.1
Strain : Escherichia coli W
Genome accession: NC_017664
Putative virulence/resistance : Virulence
Product : putative fimbrial outer membrane usher protein StfC
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2600691 - 2603333 bp
Length : 2643 bp
Strand : -
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGCCTGACCATTCTCTTTTTCGATTACGGATTCTTCCGTGGTGCATTGCGCTGGCAATGTCAGGGAGTTATAGCAGTGT
CTGGGCTGAAGACGACATTCAGTTTGATTCCCGTTTTCTGGAATTAAAAGGCGACACAAAAATTGATCTGAAGCGTTTTT
CCAGCCAGGGATATGTTGAGCCCGGAAAATACAATTTACAGGTTCAACTAAATAAACAGCCATTGGCGGAAGAGTACGAT
ATTTACTGGTATGCTGGTGAAGATGACGCGAGCAAAAGCTATGCTTGTCTGACACCGGAACTGGTAGCGCAGTTTGGTTT
AAAAGAAGACGTGGCGAACAATCTGCAATGGAGCCACGATGCTAAATGCCTGAAATCCGGTCAACTGGAAGGCATGGAAA
TTAAGGCTGATTTAAGCCAGTCCGCATTAGTCATTTCACTGCCACAGGCTTACCTCGAATATACTTATCCCGACTGGGAT
CCGCCTTCACGTTGGGATGACGGCATCTCCGGGATCGTCGCGGACTACAGCATCAACGCACAAACCCGGCACGAAGAAAA
TGGCGGTGATGATAGTAACGAGATCAGCGGCAACGGGACGGTCGGGGTTAACCTGGGGCCGTGGCGTATGCGTGCTGACT
GGCAGACTAACTATCAACATACTCGCAGTAATGATGACGATGAATTCAGCGGCGATGAAACTCAAAAAAAATGGGAGTGG
AGTCGCTACTATGCCTGGCGGGCGTTACCATCATTAAAAGCCAAACTGGCGCTGGGCGAGGATTACCTCAGATCCGATAT
TTTTGATGGTTTTAACTATGTTGGTGGCAGTGTCAGTACTGACGATCAAATGTTGCCTCCCAATCTGCGCGGCTACGCGC
CAGACATTTCCGGCGTGGCACACACCACAGCAAAAGTGACCGTCAGCCAGATGGGGCGTGTGATTTACGAAACGCAGGTT
CCGGCTGGACCGTTTCGTATTCAGGATCTTGGTGATTCTGTCTCCGGTACGTTGCATATTCGCATTGAAGAACAGAACGG
CCAGGTGCAGGAATATGACATCAGCACCGCCTCGATGCCATACCTCACTCGCCCAGGTCAGGTTCGCTATAAGATCATGA
TGGGCCGTCCGCAAGAGTGGGGACACCATGTCGAGGGTGAATTTTTTTCTGGTGCTGAAGCTTCCTGGGGGATCGCTAAC
GGCTGGTCGTTATATGGCGGCGCACTGGGAGATGAAAACTATCAGTCTGCGGCGCTTGGCGTCGGTCGCGATTTGTCTAC
ATTCGGCGCGGTCGCGTTTGATGTTACTCACTCGCACACCAAACTGGATAAAGACACCGCTTATGGCAAAGGTTCGCTGG
ACGGTAACTCCTTCCGTGTGAGTTATTCCAAAGACTTTGACCAGCTCAACAGCCGCGTTACTTTTGCTGGATATCGCTTC
TCGGAAGAGAACTTTATGACCATGAGCGAGTATCTGGATGCCAGTGACAGCGGAATGGTACGCACGGGCAACGACAAAGA
GATGTACACCGCCACTTATAACCAGAACTTCCGCGATGCGGGTGTTTCGGTTTATCTCAACTATACCCGCCATACCTACT
GGGATCGCGAGGAGCAGACAAACTACAACATCATGCTCTCGCACTATTTCAATATGGGCAGTATTCGTAATGTCAGCATC
TCGATGACTGGCTACCGTTACGAGTATGACAACCAGGCCGACAAAGGCATGTACATTTCGCTCAGTATGCCGTGGGGCGA
CAACAGTACCGTTAGCTATAACGGTAACTATGGCAGTGGGACGGACAGCAGTCAGGTCGGTTATTTCAGCCGTGTCGATG
ACGCGACTCACTATCAGTTGAACGTCGGCACCAGTGACAAACACACCAGCGTTGACGGCTATTACAGCCATGATGGTTCG
CTGGCGCAGGTTGACCTCAGTGCGAACTACCATGAAGGGCAATACACCTCTGCGGGCTTGTCGTTACAGGGCGGCGCAAC
GCTTACTGCCCACGGTGGCGCACTTCACCGTACCCAGAATATGGGCGGGACACGCTTGTTGATTGATGCCGATGGCGTTG
CCGATGTTCCGGTAGAAGGTAACGGTGCTGCTGTTTATACCAATATGTTTGGTAAAGCCGTCGTTTCTGACGTCAATAAC
TATTACCGCAATCAGGCGTATATCGACCTCAACAAACTGCCGGAAAACGCCGAAGCAACCCAGTCGGTGGTACAAGCCAC
GCTAACTGAAGGGGCGATTGGCTACCGCAAATTTGCCGTCATCAGTGGTCAAAAAGCGATGGCGGTGCTGCGTTTACAAG
ACGGCAGCCATCCTCCGTTTGGCGCAGAAGTAAAAAATGATAACGAGCAGACAGTGGGCCTTGTCGATGATGACGGCAAT
GTTTATCTGGCTGGGGTGAAACCTGGCGAACACATGAGTGTGTTCTGGAGTGGTGTTGCGCATTGCGATATCAACCTGCC
GGACCCGCTGCCTGCCGATCTGTTTAACGGCTTGTTACTGCCATGCCAGCATAAAGGCAACGTCGCGCCGGTTGTTCCTG
ATGACATAAAGCCTGTCATTCAGGAGCAGACGCAACAGGTGACACCCACCAATCCCCCTGTTTCTGTTTCAGCTAACCAA
TAA

Protein sequence :
MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYD
IYWYAGEDDASKSYACLTPELVAQFGLKEDVANNLQWSHDAKCLKSGQLEGMEIKADLSQSALVISLPQAYLEYTYPDWD
PPSRWDDGISGIVADYSINAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNYQHTRSNDDDEFSGDETQKKWEW
SRYYAWRALPSLKAKLALGEDYLRSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQV
PAGPFRIQDLGDSVSGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQVRYKIMMGRPQEWGHHVEGEFFSGAEASWGIAN
GWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYRF
SEENFMTMSEYLDASDSGMVRTGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNIMLSHYFNMGSIRNVSI
SMTGYRYEYDNQADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNVGTSDKHTSVDGYYSHDGS
LAQVDLSANYHEGQYTSAGLSLQGGATLTAHGGALHRTQNMGGTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVNN
YYRNQAYIDLNKLPENAEATQSVVQATLTEGAIGYRKFAVISGQKAMAVLRLQDGSHPPFGAEVKNDNEQTVGLVDDDGN
VYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPVVPDDIKPVIQEQTQQVTPTNPPVSVSANQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 1e-151 43
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 2e-151 43
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 2e-151 43
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 2e-151 43
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 5e-157 43
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 3e-150 42
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 2e-150 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
yfcU YP_006173920.1 putative fimbrial outer membrane usher protein StfC VFG1548 Protein 7e-152 43
yfcU YP_006173920.1 putative fimbrial outer membrane usher protein StfC VFG0884 Protein 9e-152 43
yfcU YP_006173920.1 putative fimbrial outer membrane usher protein StfC VFG0895 Protein 7e-152 43