Gene Information

Name : ECO55CA74_16730 (ECO55CA74_16730)
Accession : YP_006160466.1
Strain : Escherichia coli RM12579
Genome accession: NC_017656
Putative virulence/resistance : Virulence
Product : type III secretion system protein InvA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3467301 - 3469361 bp
Length : 2061 bp
Strand : -
Note : COG4789 Type III secretory pathway, component EscV

DNA sequence :
ATGTTTAACAAAGTTTTGGTAGGGTTAAGGAGTCATCCAGAATTAATAATTCTTGGATTAATGGTGATGATTATCGCCAT
GCTCATAATTCCATTGCCCACCTATTTAATCGACTTTTTGATTGGGCTTAACTTAACATTGGCAATACTTGTATTTTTAG
GATCATTCTATGTTGATAGGATCTTAAGCTTTTCTTCATTTCCATCAATCCTCCTTATCACAACGTTATTTCGTTTGGCG
CTGGCGATCAGTACCAGTCGACTTATACTTCTTGAGGCGGATGCTGGAGAAATTATAACGAGTTTTGGTGAGTTCGTTAT
TGGAGATAGCCTGGTAGTTGGTTTTGTTATTTTCTCCATTGTTACTATTGTTCAGTTTATCGTGATTACTAAAGGTTCGG
AACGTGTGGCTGAAGTTGCTGCCCGCTTTTCGCTTGACGGTATGCCAGGTAAACAAATGAGCATTGACGCCGATCTACGC
GCCGGGATCATTGATGCAGATTTAGCAAAAGAACGTCGTAGTGTATTAGAACGAGAGAGCCAGTTGTATGGTTCCTTTGA
TGGTGCGATGAAATTTATCAAAGGTGATGCTATTGCAAACATTATTATTATCTTTGTTAATATTATCGGTGGGCTATCAG
TAGGAGTAGGCCAAAATGGAATGGATTTCTCAACAGCGTTGACTGTCTACACAATTCTTACTGTCGGTGATGGTCTTGTT
TCTCAAATTCCAGCTTTATTAATTGCTATTAGCGCAGGATTTATCGTTACGCGCGTAAATGGCGATAGTGATAATATGGG
GCAAAATATAATGTCCCAGTTATTAAGTAATTCTTTTGTCATTGTTGTGACATGTGTCCTCGCGCTAAGTATTGGGTTGC
TTCCAGGTTTTCCCCTTCTAGTGTTTTTATGTTTGGCAGTAATCTTAGGAATTTACTTTTACTTTAAATTCAAAAAGAAA
GGGACTGAAGAAACGGTTGTTGAGGGAGATATTACCGTTGGGTTGGAACCCTATAATCAAGATGATGATATCTCATTAGG
TATCATTAATAAACTTGATCAGGTTATTACCGAAACGGTACCCTTGGTCTTGATTATGAATAGTGTACAGGCTAAAAAAT
ACACTGAAATCAATCTTGCTGATAGGATTCGTAGTCAGTTTTTTATTGAGTATGGTATCCGCATTCCCGGTATTGTCATT
CGTGAGGGGGAAGGTCTTAATGATGAAGATGTCATATTAATGCTAAATGAAGTCAGAGCTTCACAATTTAAAATTTATCA
TGATCTTGTCTTGTTGGTTGAATATTCAGATGAAGTGGTTTCGACTTTGATCAAGAAACCTGTCATTGTAAATAGTAATG
GTGAACAATATTATTGGGTTACGAAAAGTGATGCTCAAAAATTAACAAAAATTGGCTGTTATACTCGCACGGCCATGGAT
GAAATGTATAATCATTTATCTGTCTGTCTGGCTCATAATATTAATGAGTACTTTGGTGTACAAGAAACAAAATATATTCT
TGATCAATTAGAGATGAAGTATTCTGATCTATTAAAAGAAATATTAAGATATATAACCGTGCAGCGCATTTCAGAGGTAA
TTCAGCGTCTGATCCAGGAGCGAATTTCAGTGCGCAATATGCGGTTAGTTATGGAGGCCTTAGCATTATGGAGCCCACGA
GAGAAAGATATAATCACACTCGTCGAGCATGTACGAGGTACATTAGGTCGCTACATTTGCCATAAGTTTTCATATTCTGG
AGAAATTAAAGCAATTGTGATTTCGCCTGAAATAGAGGACAGAATCAGAGATGGTGTCAGGCCTACCGCTGGCGGTACTT
TTCTTAATCTCGATGCATCCGAAGCTGAGATGATTCTGGATAATTTTAAACTGGCACTTTCTGGAATCAATATTCCTATT
AAAGACATTATTTTACTGGGATCTGTGGATATTCGTCGTTTTATCAAAAAACTTATTGAATCTAGTTATCGAGACCTCGA
AGTACTTTCGTACGGGGAACTAACGGAAAATGTTCCCGTTAATATTCTGAAAACTATTTAG

Protein sequence :
MFNKVLVGLRSHPELIILGLMVMIIAMLIIPLPTYLIDFLIGLNLTLAILVFLGSFYVDRILSFSSFPSILLITTLFRLA
LAISTSRLILLEADAGEIITSFGEFVIGDSLVVGFVIFSIVTIVQFIVITKGSERVAEVAARFSLDGMPGKQMSIDADLR
AGIIDADLAKERRSVLERESQLYGSFDGAMKFIKGDAIANIIIIFVNIIGGLSVGVGQNGMDFSTALTVYTILTVGDGLV
SQIPALLIAISAGFIVTRVNGDSDNMGQNIMSQLLSNSFVIVVTCVLALSIGLLPGFPLLVFLCLAVILGIYFYFKFKKK
GTEETVVEGDITVGLEPYNQDDDISLGIINKLDQVITETVPLVLIMNSVQAKKYTEINLADRIRSQFFIEYGIRIPGIVI
REGEGLNDEDVILMLNEVRASQFKIYHDLVLLVEYSDEVVSTLIKKPVIVNSNGEQYYWVTKSDAQKLTKIGCYTRTAMD
EMYNHLSVCLAHNINEYFGVQETKYILDQLEMKYSDLLKEILRYITVQRISEVIQRLIQERISVRNMRLVMEALALWSPR
EKDIITLVEHVRGTLGRYICHKFSYSGEIKAIVISPEIEDRIRDGVRPTAGGTFLNLDASEAEMILDNFKLALSGINIPI
KDIILLGSVDIRRFIKKLIESSYRDLEVLSYGELTENVPVNILKTI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3731 NP_311758.1 EivA Not tested LIM Protein 0.0 99
invA YP_217815.1 invasion protein Virulence SPI-1 Protein 0.0 64
invA NP_457290.1 possible secretory protein (associated with virulence) Virulence SPI-1 Protein 0.0 64
invA NP_806499.1 virulence-associated secretory protein Virulence SPI-1 Protein 0.0 64
invA NP_461817.1 needle complex export protein Virulence SPI-1 Protein 0.0 64
invA AAS66860.1 InvA Not tested SSR-2 Protein 5e-155 56
ysaV AAS66840.1 YsaV Not tested SSR-1 Protein 2e-150 55
escV AAC38382.1 EscV Virulence LEE Protein 4e-89 41
escV AAC31514.1 L0035 Virulence LEE Protein 3e-89 41
escV NP_290269.1 hypothetical protein Virulence LEE Protein 4e-89 41
escV ACU09459.1 EscV protein Virulence LEE Protein 3e-89 41
ECs4569 NP_312596.1 hypothetical protein Virulence LEE Protein 4e-89 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
ECO55CA74_16730 YP_006160466.1 type III secretion system protein InvA VFG0557 Protein 0.0 64
ECO55CA74_16730 YP_006160466.1 type III secretion system protein InvA VFG1006 Protein 2e-171 61
ECO55CA74_16730 YP_006160466.1 type III secretion system protein InvA VFG0729 Protein 2e-89 41
ECO55CA74_16730 YP_006160466.1 type III secretion system protein InvA VFG0813 Protein 2e-89 41
ECO55CA74_16730 YP_006160466.1 type III secretion system protein InvA VFG0064 Protein 7e-102 41