Gene Information

Name : aadA (pUMNK88_130)
Accession : YP_006142099.1
Strain :
Genome accession: NC_017645
Putative virulence/resistance : Resistance
Product : aminoglycoside resistance protein AadA
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 114244 - 115218 bp
Length : 975 bp
Strand : +
Note : -

DNA sequence : 
ATGCGCTCACGCAACTGGTCCAGAACCTTGACCGAACGCAGCGGTGGTAACGGCGCAGTGGCGGTTTTCATGGCTTGTTA
TGACTGTTTTTTTGTACAGTCTATGCCTCGGGCATCCAAGCAGCAAGCGCGTTACGCCGTGGGTCGATGTTTGATGTTAT
GGAGCAGCAACGATGTTACGCAGCAGGGCAGTCGCCCTAAAACAAAGTTAGACATCATGAGGGTAGCGGTGACCATCGAA
ATTTCGAACCAACTATCAGAGGTGCTAAGCGTCATTGAGCGCCATCTGGAATCAACGTTGCTGGCCGTGCATTTGTACGG
CTCCGCAGTGGATGGCGGCCTGAAGCCATACAGCGATATTGATTTGTTGGTTACTGTGGCCGTAAAGCTTGATGAAACGA
CGCGGCGAGCATTGCTCAATGACCTTATGGAGGCTTCGGCTTTCCCTGGCGAGAGCGAGACGCTCCGCGCTATAGAAGTC
ACCCTTGTCGTGCATGACGACATCATCCCGTGGCGTTATCCGGCTAAGCGCGAGCTGCAATTTGGAGAATGGCAGCGCAA
TGACATTCTTGCGGGTATCTTCGAGCCAGCCATGATCGACATTGATCTAGCTATCCTGCTTACAAAAGCAAGAGAACATA
GCGTTGCCTTGGTAGGTCCGGCAGCGGAGGAATTCTTTGACCCGGTTCCTGAACAGGATCTATTCGAGGCGCTGAGGGAA
ACCTTGAAGCTATGGAACTCGCAGCCCGACTGGGCCGGCGATGAGCGAAATGTAGTGCTTACGTTGTCCCGCATTTGGTA
CAGCGCAATAACCGGCAAAATCGCGCCGAAGGATGTCGCTGCCGACTGGGCAATAAAACGCCTACCTGCCCAGTATCAGC
CCGTCTTACTTGAAGCTAAGCAAGCTTATCTGGCCTACAAAGCACATAGAGTCCTACAGGCTCGCATGCACCTCACTCGG
GGCGGAAAAGGTTGA

Protein sequence : 
MRSRNWSRTLTERSGGNGAVAVFMACYDCFFVQSMPRASKQQARYAVGRCLMLWSSNDVTQQGSRPKTKLDIMRVAVTIE
ISNQLSEVLSVIERHLESTLLAVHLYGSAVDGGLKPYSDIDLLVTVAVKLDETTRRALLNDLMEASAFPGESETLRAIEV
TLVVHDDIIPWRYPAKRELQFGEWQRNDILAGIFEPAMIDIDLAILLTKAREHSVALVGPAAEEFFDPVPEQDLFEALRE
TLKLWNSQPDWAGDERNVVLTLSRIWYSAITGKIAPKDVAADWAIKRLPAQYQPVLLEAKQAYLAYKAHRVLQARMHLTR
GGKG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aadA2 ACF06158.1 aminoglycoside 3''-adenyltransferase Not tested Tn5036-like Protein 5e-104 96
aadA2 AAK02046.1 streptomycin/spectinomycin resistance protein Not tested SGI1 Protein 1e-104 96
aadA2 AGF35027.1 AadA2 aminoglycoside adenylyltransferase Not tested SGI1 Protein 1e-104 96
aadA25 YP_005176241.1 aminoglycoside 3''-O-adenyltransferase protein Not tested ICEPmu1 Protein 4e-101 95
aadA1 ACY75515.1 aminoglycoside adenyltransferase Not tested Tn6060 Protein 6e-94 86
aadA1 CAD92142.1 aminoglycoside adenyltransferase Not tested Not named Protein 6e-94 86
aadDA1 CAJ77087.1 Aminoglycoside 3-adenylyltransferase Not tested AbaR1 Protein 4e-94 86
aadA1 YP_005797133.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 5e-94 86
aadA1 ACV89835.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR7 Protein 4e-94 86
unnamed AFV53113.1 AadA1 aminoglycoside (3') adenyltransferase Not tested AbGRI2-1 Protein 4e-94 86
aadA1 YP_005797149.1 aminoglycoside 3'-adenyltransferase Not tested AbaR4e Protein 5e-94 86
aadA1 AGK36646.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR26 Protein 4e-94 86
aadA1 YP_006098376.1 aminoglycoside adenylyltransferase Not tested Tn2411 Protein 5e-94 86
aadA1 ACN81025.1 AadA1 aminoglycoside (3')(9) adenylyltransferase Not tested AbaR5 Protein 5e-94 86
aadA1 CAJ77048.1 Aminoglycoside adenylyltransferase Not tested AbaR1 Protein 7e-97 85
aadA1 AAL08435.1 streptomycin adenyltransferase AadA1 Not tested SRL Protein 7e-88 81
aadA7 AAR21854.1 aminoglycoside (3'')(9) adenylyltransferase; AAD(3'')(9) Not tested SGI1 Protein 2e-82 75
aadA7 AAT37846.1 aminoglycoside adenyltransferase Not tested Class I integron Protein 2e-82 75
aadA7 AGF35062.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 2e-82 75
aadA7 AGK06932.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 2e-82 75
aadA7 AGK06969.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 2e-82 75
aadA7 AGK07015.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 2e-82 75
aadA7 AGK07073.1 aminoglycoside adenyltransferase Not tested SGI1 Protein 2e-82 75

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadA YP_006142099.1 aminoglycoside resistance protein AadA EU118119.1.orf1.gene Protein 6e-105 96
aadA YP_006142099.1 aminoglycoside resistance protein AadA AF047479.2.orf1.gene Protein 7e-105 96
aadA YP_006142099.1 aminoglycoside resistance protein AadA AY263741.gene.p01 Protein 7e-104 95
aadA YP_006142099.1 aminoglycoside resistance protein AadA AF174129.3.gene3.p01 Protein 3e-102 95
aadA YP_006142099.1 aminoglycoside resistance protein AadA AF294653.1.gene3.p01 Protein 7e-102 95
aadA YP_006142099.1 aminoglycoside resistance protein AadA AJ584652.2.gene7.p01 Protein 5e-94 88
aadA YP_006142099.1 aminoglycoside resistance protein AadA AM932669.1.gene3.p01 Protein 1e-92 87
aadA YP_006142099.1 aminoglycoside resistance protein AadA Y18050.2.gene6.p01 Protein 4e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA AF313471.1.gene3.p01 Protein 2e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA AY339625.2.gene17.p0 Protein 2e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA JN596991.2.gene3.p01 Protein 4e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA FR748153.1.gene5.p01 Protein 4e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA AY123251.gene3.p01 Protein 2e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA NC_010410.6003168.p0 Protein 2e-94 86
aadA YP_006142099.1 aminoglycoside resistance protein AadA NC_010410.6003170.p0 Protein 4e-97 85
aadA YP_006142099.1 aminoglycoside resistance protein AadA U37105.2.gene4.p01 Protein 3e-86 76
aadA YP_006142099.1 aminoglycoside resistance protein AadA NC_003198.gene.p01 Protein 2e-46 47

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aadA YP_006142099.1 aminoglycoside resistance protein AadA VFG1026 Protein 4e-88 81