Gene Information

Name : iuvC (ECNA114_4699)
Accession : YP_006141822.1
Strain : Escherichia coli NA114
Genome accession: NC_017644
Putative virulence/resistance : Virulence
Product : Citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase,alpha subunit, aerobactin biosynthesis protein / Siderophore synthetase superfamily, group C / Siderophore synthetase component, ligase
Function : -
COG functional category : -
COG ID : -
EC number : 6.3.2.27
Position : 4845987 - 4847729 bp
Length : 1743 bp
Strand : -
Note : -

DNA sequence :
ATGAATCACAAGGACTGGGATTTTGTTAACCGTCGGCTGGTGGCAAAAATGTTGTCTGAGATGGAGTATGAGCAGGTTTT
CCACGCGGAATCTCAGGGCGATGACCACTACTGCATTAACCTGCCGGGAGCACAATGGCGCTTCATCGCTGAACGTGGTA
TCTGGGGCTGGCTGTGGATTGATGCCCAAACGTTGCGCTGCACGGACGAACCAGTACTGGCGCAGACGCTGCTGATGCAG
CTAAAGCCGGTGCTGTCAATGAGTGATGCCACTGTTGCAGAGCATATGCAGGATTTGTATGCCACGCTACTGGGCGACCT
GCAACTGCTGAAGGCCCGTCGCGGACTGAGTGCCAGTGACCTGATTAATCTTGATGCCGATCGTCTGCAATGCCTGCTGA
GCGGTCATCCTAAATTCGTTTTTAATAAAGGTCGCCGTGGCTGGGGCAAAGAGGCGCTGGAACGATATGCGCCAGAGTAT
ACCAACACCTTCAGACTGCACTGGCTGGCGGTAAAACGTGAACATATGATCTGGCGCTGCGATAACGATCTGGATATTCA
GCAGTTGTTGACTGCCGCAATGGATCCGCAGGAGTTTACACGCTTCAGTCAGGTCTGGCAGGAAAACGGACTGGATCACA
ACTGGCTGCCGCTGCCGGTACATCCGTGGCAGTGGCAGCAAAAAATCGCTACCGACTTCATCGCTGATTTTGCCGAAGGC
AGGATGGTGTCTCTCGGCGAGTTTGGCGACCAGTGGCTCGCCCAGCAGTCGCTGCGTACCCTGACCAACGCCAGTCGCCG
GGGCGGGCTGGATATCAAGCTGCCGCTGACCATCTACAACACCTCATGCTACCGGGGGATCCCTGGCAGATACATCGCTG
CCGGACCACTGGCTTCACGCTGGCTACAACAGGTTTTTGCGACCGACGCCACCCTGGTGCAAAGCGGCGCAGTGATACTT
GGTGAACCGGCTGCAGGCTATGTCTCCCATGAAGGCTATGCCGCGCTTGCCCGGGCTCCCTATCGCTACCAGGAAATGCT
TGGTGTTATCTGGCGGGAGAATCCGTGCCGCTGGCTGAAACCGGATGAAAGTCCGGTTCTGATGGCAACACTGATGGAGT
GCGACGAAAACAATCAGCCGCTGGCAGGCGCATATATAGACCGCTCCGGGCTGGACGCTGAAACCTGGCTTACGCAACTG
TTCCGGGTGGTCGTGGTTCCTCTGTATCACCTGCTTTGCCGCTACGGTGTCGCGCTTATTGCACATGGACAAAATATAAC
TCTCGCCATGAAAGAGGGGGTTCCACAGCGTGTTCTGCTGAAAGACTTCCAGGGCGATATGCGACTGGTGAAAGAAGAGT
TCCCCGAAATGGACTCTTTGCCTCAGGAGGTTCGTGATGTTACATCCCGCCTGAGTGCGGACTACTTAATCCATGATTTG
CAGACGGGTCACTTCGTGACAGTACTGCGTTTTATTTCGCCACTGATGGTTCGTCTTGGCGTACCTGAAAGGCGATTTTA
TCAACTGCTGGCAGCAGTGTTGAGTGATTACATGAAAAAACATCCACAAATGTCAGAGCGTTTTGCGCTTTTCTCACTTT
TCAGGCCACAAATCATTCGCGTGGTGCTGAACCCGGTAAAACTGACCTGGCCTGATCTGGATGGCGGCAGCCGCATGCTG
CCGAATTACCTTGAGGATCTGCAAAATCCGCTGTGGCTGGTAACTCAGGAATATGAATCATGA

Protein sequence :
MNHKDWDFVNRRLVAKMLSEMEYEQVFHAESQGDDHYCINLPGAQWRFIAERGIWGWLWIDAQTLRCTDEPVLAQTLLMQ
LKPVLSMSDATVAEHMQDLYATLLGDLQLLKARRGLSASDLINLDADRLQCLLSGHPKFVFNKGRRGWGKEALERYAPEY
TNTFRLHWLAVKREHMIWRCDNDLDIQQLLTAAMDPQEFTRFSQVWQENGLDHNWLPLPVHPWQWQQKIATDFIADFAEG
RMVSLGEFGDQWLAQQSLRTLTNASRRGGLDIKLPLTIYNTSCYRGIPGRYIAAGPLASRWLQQVFATDATLVQSGAVIL
GEPAAGYVSHEGYAALARAPYRYQEMLGVIWRENPCRWLKPDESPVLMATLMECDENNQPLAGAYIDRSGLDAETWLTQL
FRVVVVPLYHLLCRYGVALIAHGQNITLAMKEGVPQRVLLKDFQGDMRLVKEEFPEMDSLPQEVRDVTSRLSADYLIHDL
QTGHFVTVLRFISPLMVRLGVPERRFYQLLAAVLSDYMKKHPQMSERFALFSLFRPQIIRVVLNPVKLTWPDLDGGSRML
PNYLEDLQNPLWLVTQEYES

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
iucC AAK71633.1 IucC Virulence SHI-3 Protein 0.0 99
iucC YP_002414044.1 Aerobactin siderophore biosynthesis protein Virulence Not named Protein 0.0 99
iucC NP_839221.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucC NP_709456.1 siderophore biosynthesis protein Virulence SHI-2 Protein 0.0 99
iucC AAD44748.1 IucC Virulence SHI-2 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
iuvC YP_006141822.1 Citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase,alpha subunit, aerobactin biosynthesis protein / Siderophore synthetase superfamily, group C / Siderophore synthetase component, ligase VFG0617 Protein 0.0 99
iuvC YP_006141822.1 Citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase,alpha subunit, aerobactin biosynthesis protein / Siderophore synthetase superfamily, group C / Siderophore synthetase component, ligase VFG1083 Protein 0.0 99
iuvC YP_006141822.1 Citrate:6-N-acetyl-6-N-hydroxy-L-lysine ligase,alpha subunit, aerobactin biosynthesis protein / Siderophore synthetase superfamily, group C / Siderophore synthetase component, ligase VFG0938 Protein 0.0 99