Gene Information

Name : NRG857_20800 (NRG857_20800)
Accession : YP_006122502.1
Strain : Escherichia coli NRG 857C
Genome accession: NC_017634
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4439025 - 4441028 bp
Length : 2004 bp
Strand : +
Note : COG0550 Topoisomerase IA

DNA sequence :
ATGAAGCTCTTTCTCTGCGAAAAACCCAGTCAGGGACGCGATATTGCCGCTGTGCTGGGTGCGACAAAGAAAATGCCGGG
GCATCAAACCGGAAACGGCGTGTGCGTCACCTGGGGTTTTGGTCATCTGCTGGAGCAGGCCAGCCCGGACGCCTACGGTG
AACAGTTCGGCGTTCCCTGGCGTACTGACGTGTTGCCGGTATTGCCGACAATGTGGCAAATGCGGGTTAAACCGGATGCA
GCAGCTCAGTTCTCCGTCATCCAGAAACTGCTGAAACAGGCTGATACGGTAGTGATTGCCACCGATGCGGATCGGGAAGG
AGAGGTGATTGCTCGTGAAATCCTCGATTATTGTCACTATCAGGGAAAAGTTGAGCGGTTATGGCTCTCGGCGCTGGATG
AGGCCAGCGTTCGCGCCGCGCTGGCGACGATAAAGCCCGGAAGTACGACTTTACCCTACTATTTAGCCGGGCTTGGCCGC
GCCCGGGCTGACTGGCAAATAGGTATGAACATGACGCGGCTATATTCGGTCAAGGCCCGGGAGAACGGCTACGGTAGCGT
TTTATCCGTGGGGCGGGTGCAGACGCCGACGCTTAACCTGATCGTGGTACGCGATCGCGATATTGTGCAGTTTGTTCCGA
AGCCCTACTGGAATGTTGTGGCGCAGCTGGCGGCGGGAGGAATTGCGTTTCAGGCGCAGTGGGTGCCAGCAGAGGCGTAT
TGTGATGAGGAAAAACGCTGTATCAACCCGACAGCGGCGCAGCAGGTGGTTCAGCTTTGCCAGAAAACCGGACAGGCGAC
GGTGGCAGAGGTTGAGACCAAAAGGGAAACGGAGTCTGCTCCGCTGGCATTTGATCTCGGTACGCTACAACAAGCCTGTT
CCCGCCGTTTCGGTTATGGCGCTCAGCAGGTGCTGGATATTGCGCAGGCTTTGTATGAAACCTACAAAGCAACCACGTAC
CCTCGTACCGATTGCGGCTACCTGCCAACATCCATGCGTGGCGAGATCGGACAGGTGATGTCTTCGATACAGCAAAGCGA
TCCCGCTTTATCTGCGATCATCTCGCGGCTTGATATGAAGCATGTTTCCCGTATCTGGAATGACAAAAAAATCACCGCGC
ACCACGGTATTATCCCGACGAAGCAACCCTGTGATCTGGCGAAAATGAGTGAGCAGGAGCGCAACGTTTACCAGCTTATC
CGTCTGCATTATCTGGCCCAGTTCCTGCCGAACCATGAAGTGGATGCCACGCGGGTTTCGCTGCATTGTGGCGGTCAGTT
ATTTAAGACCAGCGGTAAAGCTGTGGTCGTTGCTGGCTGGAAGAGTTTGTTTGGTAAGGATGCTGACGAGGATGCAGGCG
ATGCCGGTGATAAAGCACGGTTACCTGCAATGGCTAAAGGGAGCTTGTGCCAGGTCACCGGCGCGGAAGCAAAACCGCAG
CAGACAAAACCACCTGAGCACTATACGGAAGGGACGTTGATTGCAGCGATGAAGAATGCAGCGCAGTTCGTTACCGATCC
GCGTCTTAAAAAGATCCTCAAAGAAAATGCGGGGCTGGGAACGGAAGCAACCCGGGCTGGAGTAATTGAAACGCTCCTGA
AGCGTGGATTTGTGGTGAAGAAAGGCAAGCATCTGCTGGCGACACCTATCGCGGCTGATTTGATGGCTGTGTTACCGGCA
CAGCTTAAAGATCCGGGTATGACGGCGCTCTGGGAGCAATCACTGGATGACATTGCTGAAGGCCGGATGTCGCTTGATGA
CTTTATGGCGAAACAGTCAGCCTGGACAATGCAACTGGTGGCAAAGGGGCAGCATCAGACGGTTAAGATCACGTTACCAC
CTTCTCCGCCGTGCCCGATCTGCGGTGGGGTAACGCGGCAGCGCACGGGGAAATCAGGCTCATTCTGGGGATGCGTCAAC
TACCCTGACTGCAACGGGATTGTGAATGTCGGGGCGAAGAAGCCTGGTCGTCGGCGGAAAAGTCCGGCAAAGAAAAGTGT
CTGA

Protein sequence :
MKLFLCEKPSQGRDIAAVLGATKKMPGHQTGNGVCVTWGFGHLLEQASPDAYGEQFGVPWRTDVLPVLPTMWQMRVKPDA
AAQFSVIQKLLKQADTVVIATDADREGEVIAREILDYCHYQGKVERLWLSALDEASVRAALATIKPGSTTLPYYLAGLGR
ARADWQIGMNMTRLYSVKARENGYGSVLSVGRVQTPTLNLIVVRDRDIVQFVPKPYWNVVAQLAAGGIAFQAQWVPAEAY
CDEEKRCINPTAAQQVVQLCQKTGQATVAEVETKRETESAPLAFDLGTLQQACSRRFGYGAQQVLDIAQALYETYKATTY
PRTDCGYLPTSMRGEIGQVMSSIQQSDPALSAIISRLDMKHVSRIWNDKKITAHHGIIPTKQPCDLAKMSEQERNVYQLI
RLHYLAQFLPNHEVDATRVSLHCGGQLFKTSGKAVVVAGWKSLFGKDADEDAGDAGDKARLPAMAKGSLCQVTGAEAKPQ
QTKPPEHYTEGTLIAAMKNAAQFVTDPRLKKILKENAGLGTEATRAGVIETLLKRGFVVKKGKHLLATPIAADLMAVLPA
QLKDPGMTALWEQSLDDIAEGRMSLDDFMAKQSAWTMQLVAKGQHQTVKITLPPSPPCPICGGVTRQRTGKSGSFWGCVN
YPDCNGIVNVGAKKPGRRRKSPAKKSV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 0.0 64
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 0.0 64
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 0.0 64
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 0.0 57
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 1e-178 53
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 1e-177 51
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 6e-166 51
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 7e-170 50
topB AAW83109.1 TopB Not tested GGI Protein 2e-123 41