Gene Information

Name : NRG857_17645 (NRG857_17645)
Accession : YP_006121871.1
Strain : Escherichia coli NRG 857C
Genome accession: NC_017634
Putative virulence/resistance : Virulence
Product : Outer membrane usher protein lpfC precursor
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3732418 - 3734949 bp
Length : 2532 bp
Strand : -
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGCATTGGATGCATTTACCTCTTGATCACTACAGAGCGCATTTTTCTTTCTCACTGTTGGCATTAACTATTGCCAGCGC
GTTACCTGCGTACGGCGGAAAATTCAACCCTAAATTTCTTGAAAATGTTCAGGGTATTGATCAACACGTCGATTTGTCAG
TTTACGACTCTCCTGTCGGCCAGCAAATACCCGGTAAATATCGGGTATTTGTGTTTGTAAACGAAGAAAAAATGGCTTCC
CGGACGCTGGATTTTAGTACTGCCAGCGAAGCACAACGCAAAGCCAGCGGCGAGTCGCTTATGCCTTGCCTTAGCCGTGT
TCAACTGGAAGAAATGGGCGTGCGCATCGACAGCTTTCCGGCACTGAAGATATTGCCACCGGAAGCCTGCGTAGCGTTTG
ATGAAATCATTCCCCAGGCCACCAGTCGTTTTGATTTTAATACTCAGACGTTGCATCTTACCTTTCCACAGGCAGCAATG
ATGATGACCGCTCGTGGCACGGTTGATCCTTCTCGCTGGGACGAAGGAATACCTGCGCTGTTACTGGACTACAGCTTTAG
TGGCAGCAATGGTCGCAACGAAGGTTCCGGTTCATCTCCAGATTCGACCAGTGACAGTTATTACCTGAACTTGCGCAGCG
GTTTGAACGTGGGGCCGTGGCGTTTACGTAATAACAGTATCTGGAACCGTACCGATGGCAAAAATCAATGGGATAACGTT
GGTACATCGTTAAACCGGGCGATTATTCCACTCAAGTCACAGATAACATTGGGTGATACCGCCACGCCTGGCGAGATTTT
TGATAGCGTACAAATGCGCGGGACATTATTGGCATCCGACGATGAAATGTTGCCGGATAGCCAGCGTGGCTTTGCTCCGG
TGGTGCGTGGCATCGCCAAAAGTAACGCTGAAGTGAGTATCGAACAGAACGGATATGTTATTTATCGTACCTTTGTTCAG
CCGGGCGCATTTGAGATTAACGATCTCTACGCAACCTCCGGCAGCGGTGACTTGACGGTGATCATTAAAGAATCTGACGG
AAGTGAACAACGTTTTATTCAACCATTTTCGGCAGTGGCGATTTTCCAGCGTGAAGGGTATCTGAAATACAGCCTTGCTG
CCGGTGAGTATCGTGCCGGTAATTACGACAGCGGTAAACCGCGATTCGGGCAATTTACTGCCATGTACGGCTTGCCGTGG
GGAATGACCGCCTATGGTGGTGCGTTGCTATCGGCAGACTACAACGCTTTAGCTCTGGGGCTGGGGAAGAACTTCGGCAC
CATTGGTGCGGTATCGGTGGATGTCACCCAGGCGAAAAGTCAGTTACGCAACAATGAAAAAGATGAAGGGCAGTCTTATC
GTTTCCTCTATTCGAAAAGTTTTGAGGGCGGTACCGACCTGCGTCTGTTGGGCTACAAGTACTCAACCAGCGGTTATTAC
ACCTTCCAGGAAGCGACCGATGTCCGTAGTGACGCCGACAGTGACTATCGGCGTTATCATAAGCGCAGCCAGATACAAGG
TAACATCACTCAGCAACTGGGAGACTACGGTTCTGTTTACTTCAATATGACGCAGCAGGATTACTGGAACGTTGATGGTA
AGGAGAACTCCTTAAGCGCTGGTTATCACGGTCATATTGGTCGTGTGAATTACAGTATCGCCTATACCTGGACGAGAAGC
CCTGAATGGGATGAAGACGATCGACTGTGGTCATTTAGCCTCTCAATACCGCTGGGTGGCGCATGGGGCAGTTATCGTAT
GACCACCGACCAGAACGGCAAGACGTCACAACAGGCCTCTGTCAGCGGCACATTACTGGAAGATCGTAACTTGAACTATA
ACGTTCAGCAGGGTTATACCAGTAATGGGGTTGGCAACAGTGGTAGTGTCAACATGGGTTATATGGGAGGTTCTGGCAAC
ATTGACGTGGGTTATAACTATTCCAAAGATAACCAACAAGTTAACTATGGTGTGCGTGGTGGAGTCATTGTTCACAGTGA
AGGTATCACTCTCTCGCAACCCTTGGGTGAAAGTCTGGCAATTGTTTCTGCGCCGGGTGCGCGTGGTGGACATGTAGTAA
ATAGCAGCGGCGTTGAAGTTGACTGGATGGGCAACGCAGTGGTGCCGTATCTCACGCCATATCGTGAAACCATTGTGGAA
TTGCGCAGCGACACGTTAGGGCAAAACGTTGAATTACAGGAAGCGTTTCAGAAAGTCGTTCCAACGCGTGGGGCGATAGT
CCGTTCCCGCTTTGATACGCGTGTCGGTTATCGTGTGCTGATGAGTTTGAAACGGGCGAATGGCAACGCAGTACCGTTTG
GTGCTACCGCAGCGTTAAGTGATGAGAGCAAACCTGCCAGCAGCATTGTGGGTGAAGAAGGACAGCTTTATATCAGCGGG
ATGCCAGAAGAGGGCGAATTGCAGGTGAGCTGGGGGCACGAGCAGGCGCAACGTTGCCGCGTGCCATTCCGCTTGCCAGA
GAAAAAGGATAATTCGGGTATCGTGATGGTTAATGCGGTATGCGATAAATAA

Protein sequence :
MHWMHLPLDHYRAHFSFSLLALTIASALPAYGGKFNPKFLENVQGIDQHVDLSVYDSPVGQQIPGKYRVFVFVNEEKMAS
RTLDFSTASEAQRKASGESLMPCLSRVQLEEMGVRIDSFPALKILPPEACVAFDEIIPQATSRFDFNTQTLHLTFPQAAM
MMTARGTVDPSRWDEGIPALLLDYSFSGSNGRNEGSGSSPDSTSDSYYLNLRSGLNVGPWRLRNNSIWNRTDGKNQWDNV
GTSLNRAIIPLKSQITLGDTATPGEIFDSVQMRGTLLASDDEMLPDSQRGFAPVVRGIAKSNAEVSIEQNGYVIYRTFVQ
PGAFEINDLYATSGSGDLTVIIKESDGSEQRFIQPFSAVAIFQREGYLKYSLAAGEYRAGNYDSGKPRFGQFTAMYGLPW
GMTAYGGALLSADYNALALGLGKNFGTIGAVSVDVTQAKSQLRNNEKDEGQSYRFLYSKSFEGGTDLRLLGYKYSTSGYY
TFQEATDVRSDADSDYRRYHKRSQIQGNITQQLGDYGSVYFNMTQQDYWNVDGKENSLSAGYHGHIGRVNYSIAYTWTRS
PEWDEDDRLWSFSLSIPLGGAWGSYRMTTDQNGKTSQQASVSGTLLEDRNLNYNVQQGYTSNGVGNSGSVNMGYMGGSGN
IDVGYNYSKDNQQVNYGVRGGVIVHSEGITLSQPLGESLAIVSAPGARGGHVVNSSGVEVDWMGNAVVPYLTPYRETIVE
LRSDTLGQNVELQEAFQKVVPTRGAIVRSRFDTRVGYRVLMSLKRANGNAVPFGATAALSDESKPASSIVGEEGQLYISG
MPEEGELQVSWGHEQAQRCRVPFRLPEKKDNSGIVMVNAVCDK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 2e-157 44
lpfC YP_006098365.1 fimbrial outer membrane usher protein Not tested Tn2411 Protein 3e-136 41
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 4e-158 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NRG857_17645 YP_006121871.1 Outer membrane usher protein lpfC precursor VFG0454 Protein 0.0 74
NRG857_17645 YP_006121871.1 Outer membrane usher protein lpfC precursor VFG0876 Protein 2e-162 44
NRG857_17645 YP_006121871.1 Outer membrane usher protein lpfC precursor VFG0446 Protein 5e-148 41
NRG857_17645 YP_006121871.1 Outer membrane usher protein lpfC precursor VFG1645 Protein 2e-158 41
NRG857_17645 YP_006121871.1 Outer membrane usher protein lpfC precursor VFG0912 Protein 3e-158 41