Gene Information

Name : NRG857_11835 (NRG857_11835)
Accession : YP_006120717.1
Strain : Escherichia coli NRG 857C
Genome accession: NC_017634
Putative virulence/resistance : Virulence
Product : outer membrane usher protein YfcU
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2469350 - 2471998 bp
Length : 2649 bp
Strand : -
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGCCTAATCACTCAAATTTTCGGCTGCGGGGAATCGCCTGCTATATTGCGCTGGCAATCTCTGGTGGGTCAGTCAATGC
ATGGGCTGATGATTCAATTCAATTTGACCCCCGTTTCCTTGAGTTAAAGGGCGATACGAAAATTGATCTCGGTAAGTTTT
CAAAAAAAGGGTATGTCGACGCGGGTAAATATAATTTACGTGTATTTATAAATAAACAACCCCTTTCTGATGAATACGAC
ATTAACTGGTACGTCTCTGAAAACGATCCAACAAAAAACTATGCCTGCCTGACACCTGAGTTAGTGGCGGCGCTGGGGCT
GAAAGAAGGGATAGCAAAAAGCCTGCAGTGGACGCACAACGATGAATGCCTTAAACCAGGTCAATTAGACGGGATGGAAG
TCGAGAATGATTTAAGCCAGTCGGCGTTGCTGCTGACAGTGCCACAGGCTTACCTCGAATATACCAGCAGCGACTGGGAC
CCTCCCTCACGTTGGGACGACGGTATTCCTGGCCTGATTGCCGACTACAGCCTCAATGCGCAAACTCGCCACCAGGAGCA
GGGGGGCGAGGACTCACATGATATCAGCGGCAACGGTACCGTTGGGGCGAACCTGGGGGCATGGCGTTTCCGTGCAGACT
GGCAAAGTGATTATCAGCACACCCGCAGCAACGATGACGACGATGACAGCAGTAACAGCACAACGAGTAAACACTGGGAC
TGGAGTCGTTATTACGCCTGGCGAGCCTTGCCCTCTTTAAAAGCGAAGCTGTCGCTGGGGGAAGATTATCTCAATTCCGA
TATTTTCGACGGCTTTAACTATATCGGCAGCAGCGTCAGCACCGATGACCAGATGCTGCCGCCCAACCTGCGCGGCTATG
CACCGGATGTTTCCGGCGTGGCGCACAGCAGTGCAAAAGTCACCATTAGCCAGATGGGCCGGGTACTTTACGAAACCCAG
GTTCCAGCCGGGCCATTCCGCATTCAGGATATCGGCGACTCCGTCTCCGGCACACTGCACGTCCGCGTTGAAGAACAGAA
TGGTCAGGTGCAGGAATATGACGTTACGACCGCATCTGTGCCATTCCTCACGCGCCAGGGGCAGGTGCGTTACAAAGTGA
TGATGGGGCGTCCGGAAGACTGGAACCACAAGACCGAAGGCGGCTTTTTCTCCGGCGGAGAAGCGTCATGGGGGGTGGCA
GATGGCTGGTCGCTCTACGGTGGTGCGCTGGCAGATAAACACTATCAGTCGGCGGCGATGGGGGTGGGGCGCGACCTCGC
ACAGTTTGGCGCGCTGGCGTTCGATGTGACTCACTCGCACGTCAACCTGGATCATGACAGCGCATACGGCAAAGGAAAAC
TGGACGGCAACTCCTTTCGCGTGAGCTATGCCAAAGACTTTGACGAACTCAACAGCCGCGTCACCTTTGCAGGCTACCGT
TTCTCCGAAAAGAACTTCATGACCATGAGCGAGTATCTGGACGCGAACCAGTCGGACATGGCGCGGACCGGTAACGACAA
AGAGATGTATACGATCACCTATAACCAGAACTTTGCCGCTGCGGGTGTCTCTATCTATCTCAACTACTCCCATCGTACTT
ACTGGGATCGCCCGGAACAGACAAACTATAACCTGATGTTTTCCCACTATTTTAATATGGGGAGCATTCGCAACATGAGC
ATCTCGGTGACCGGCTATCGCTACGAATATGACGATAATGCGGATAAGGGGATGTACCTCAGTATGAGCATTCCGTGGAG
CGACAGCAGCACCGTGACCTACAACGGTTCCTACGGCAGCGGGTCGGACAGCAGCCAGGTCGGTTACTTTAAGCGCGTCG
ATGACGCAACGCACTACCAGGTTAACGTTGGCACCAGCGAGCAGCACGGCAGCGTGGATGGTTATCTGAGCCACGACGGT
TCGCTGGCGAAGGTTGATCTCAGCGCCAACTACCATGAAGGGGAATACCGTTCGGCTGGGATCGCCTTACAGGGCGGGGC
AACGCTGACCGCGCATGGTGGGGCGCTGCACCGTACCCAGAACATGGGCGGCACGCGCCTGCTGATTGATGCCGACGGGA
TTGCCAACGTGCCGGTCGAAAGCAACGGCGCGCCGGTGTACACCAATATGTTTGGCAAGGCGGTGGTCGCCGATATTAAC
AACTACTATCGCAATCAGGCGTATATCGATTTAAACAACTTGCCGGAAGATGCGGAAGCCACCCAGTCGGTGGTGCAGGC
GACTCTGACGGAAGGCGCAATCGGCTATCGCAAATTCAAAGTGATCAGCGGGCAAAAAGCGATGGCGGTACTGAGGTTGC
GTGACGGTAGCTACCCGCCGTTTGGCGCGGAAGTGAAAAATGACGAGCAGCAGCAGGTTGGCATTGTGGATGATGAAGGC
AATGTCTATCTGGCGGGGGTCAATGCGGGCGAGCATATGATGGTGTTCTGGGAAGGCAGCGCACAATGCGAGATCGTATT
GCCGAAGCCGCTACCTGCCGATTTGTTCAGCGGCCTGTTGTTGCCGTGTGAACAAAAGGGAACGGCAGCCCCTGATTCTT
CAGCACCAGAAATTAAGCCTGTTATTCAGGACCAGACGCGGCAAGTCACACCAACGGAAGCGCCGACGTCAATTTCAGCA
ACTCAATAA

Protein sequence :
MPNHSNFRLRGIACYIALAISGGSVNAWADDSIQFDPRFLELKGDTKIDLGKFSKKGYVDAGKYNLRVFINKQPLSDEYD
INWYVSENDPTKNYACLTPELVAALGLKEGIAKSLQWTHNDECLKPGQLDGMEVENDLSQSALLLTVPQAYLEYTSSDWD
PPSRWDDGIPGLIADYSLNAQTRHQEQGGEDSHDISGNGTVGANLGAWRFRADWQSDYQHTRSNDDDDDSSNSTTSKHWD
WSRYYAWRALPSLKAKLSLGEDYLNSDIFDGFNYIGSSVSTDDQMLPPNLRGYAPDVSGVAHSSAKVTISQMGRVLYETQ
VPAGPFRIQDIGDSVSGTLHVRVEEQNGQVQEYDVTTASVPFLTRQGQVRYKVMMGRPEDWNHKTEGGFFSGGEASWGVA
DGWSLYGGALADKHYQSAAMGVGRDLAQFGALAFDVTHSHVNLDHDSAYGKGKLDGNSFRVSYAKDFDELNSRVTFAGYR
FSEKNFMTMSEYLDANQSDMARTGNDKEMYTITYNQNFAAAGVSIYLNYSHRTYWDRPEQTNYNLMFSHYFNMGSIRNMS
ISVTGYRYEYDDNADKGMYLSMSIPWSDSSTVTYNGSYGSGSDSSQVGYFKRVDDATHYQVNVGTSEQHGSVDGYLSHDG
SLAKVDLSANYHEGEYRSAGIALQGGATLTAHGGALHRTQNMGGTRLLIDADGIANVPVESNGAPVYTNMFGKAVVADIN
NYYRNQAYIDLNNLPEDAEATQSVVQATLTEGAIGYRKFKVISGQKAMAVLRLRDGSYPPFGAEVKNDEQQQVGIVDDEG
NVYLAGVNAGEHMMVFWEGSAQCEIVLPKPLPADLFSGLLLPCEQKGTAAPDSSAPEIKPVIQDQTRQVTPTEAPTSISA
TQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 2e-146 43
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 2e-140 42
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 2e-139 42
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 2e-139 42
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 2e-140 42
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 2e-140 42
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 2e-140 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NRG857_11835 YP_006120717.1 outer membrane usher protein YfcU VFG1548 Protein 1e-140 42
NRG857_11835 YP_006120717.1 outer membrane usher protein YfcU VFG0884 Protein 9e-141 42
NRG857_11835 YP_006120717.1 outer membrane usher protein YfcU VFG0895 Protein 9e-141 42