Gene Information

Name : NRG857_01105 (NRG857_01105)
Accession : YP_006118586.1
Strain : Escherichia coli NRG 857C
Genome accession: NC_017634
Putative virulence/resistance : Virulence
Product : putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 250336 - 253098 bp
Length : 2763 bp
Strand : -
Note : COG0542 ATPases with chaperone activity, ATP-binding subunit

DNA sequence :
ATGATCCAGATTGATTTAGCCACGCTCGTAAAGCGGCTTAACCCCTTTGCAAAACAGGCGCTGGAAATGGCTGCCTCGGA
GTGTATGAGCCAGCAGGCCAGTGAGATCACCGTTGCCCATGTGCTGTTACAGATGCTGGCAATCCCGCGCAACGACGTAA
GGGTGATTGCCGAACGCACAGGCATCAGTGCGGAGGATTTACGCCAGGCGCTGACCGTGGAGAGTTATCCCGGTGGACGT
TCCGCCGAAGGCTATCCCAGCTTCTCCCCGATGCTGATCGAATGGCTCAAGGAGTCATGGCTGCTGGCCTCAGCCCAGAT
GCAGCACAGCGAACTGCGCAGCGGCGTCCTGCTGCTTACTCTGCTGCATTCACCGCTGCGCTATATTCCACCCGCTGCTG
CCCGTCTGCTGACGGCCATAAACCGCGACCAGTTACAGCAGGATTTCGCAGCATGGACAAAAGAATCCGCCGAATCCGTG
GATCTGGCTGGCGGGCAAACGCCCCGGGCAACGGAAACCGGCGACACCCTGCTTGCCCGCTACGCCAAAAACATGACCGC
AGACGCCCGTAACGGCAGGCTTGACCCGGTACTGTGCCGCGACTATGAAATCGACCTGATGATCGACATTCTCTGCCGCC
GCCGTAAAAACAATCCGGTGGTAGTGGGCGACGCAGGCGTGGGTAAAAGCGCGCTGATTGAAGGGCTGGCGCTGCGCATC
GTGGCAGGCCAGGTGCCGGACAAGCTGAAAAACACCGATATCATGACCCTTGACCTGGGCGCATTGCAGGCCGGTGCGTC
GGTGAAAGGTGAGTTTGAAAAACGCTTCAAGGGGCTGATGGCGGAGGTCATTTTCTCCCCGGTGCCGGTCATTCTGTTTA
TCGACGAAGCACATACCCTGATTGGCGCGGGCAACCAGCAGGGCGGGCTGGATATATCCAACCTGCTCAAACCAGCGCTG
GCGCGCGGCGAGCTGAAAACCATCGCCGCCACCACCTGGAGCGAGTACAAAAAATATTTCGAGAAAGATGCAGCTTTGTC
GCACCGCTTCCAGTTAGTGAAGGTCAGCGAACCCAACGCTGCCGAAGCCACCATTATTCTGCGCGGTTTGTTGGCGGTCT
ATGAACAGTCTCACGGCGTGCTGATTGATGATGACGCCTTGCAGGCCGCTGCGACACTGAGCGAGCGTTATCTCTCCGGG
CGTCAGTTGCCGGACAAAGCCATTGATGTGCTGGACACCGCCTGCGCCCGTGTGGCCATCAACCTGTCATCGCCGCCAAA
ACAAATCTCGGCACTGACCACCCTGAGCCACCAGCAGGAGGCAGAAATTCGCCAGCTTGAGCGCGAGCTTCGCATCGGGC
TGCGTACCGACACCTCACGAATGACTGAGGTGTTGGAGCAGTATGATGAAACGCTGTCGGCGCTGGACGAACTGGAAGTC
GCCTGGCAGCAGCAGCAGACGCTGGTACAGGAAATTATCGCGCTGCGCCAGCAGTTACTGGGCGTGGCAGAAGACGACGT
TGCGTCGTTGCCGGACGCAGATGCCGTGGAGGATACGCCGCCAGAGGCAGAACAGGATAGTACCGATGCCGAATCGGCTG
ATGATGCAGGCAGCGTACAGCCGGAAGAGACCGCTGAAACAGTTTCCCCGGTACAACGGCTGGCACAACTCACTGCCGAA
CTGGACGCCCTGCATAACGACCAGTTGCTGGTTTCCCCGCATGTCGATAAAAAACAGATTGCAGCGGTGATTGCCGAATG
GACCGGCGTGCCACTTAACCGCCTGTCACAGAATGAGATGTCGGTCATCACCGACCTGCCGGTATGGCTCGGCGGCACCA
TCAAAGGCCAGGACCTGGCGATTGCCAGCCTGCATAAACACCTGCTGACCGCACGCGCCGACCTGCGCCGTCCGGGACGC
CCGCTTGGTGCGTTCCTGCTGGCTGGCCCCAGCGGCGTGGGTAAAACCGAAACCGTCCTGCAACTGGCGGAACTGCTCTA
TGGCGGACGTCAATACCTGACCACCATCAATATGTCTGAGTTCCAGGAGAAACACACCGTTTCGCGGCTGATTGGCTCTC
CTCCGGGTTATGTCGGCTACGGTGAAGGCGGCGTACTGACCGAAGCGATTCGCCAGAAACCGTACTCGGTGGTGCTGCTC
GATGAAGTAGAAAAAGCGCACCCGGATGTACTCAACCTGTTCTACCAGGCGTTTGACAAGGGCGAGATGGCAGACGGTGA
AGGCCGCCTGATTGACTGTAAAAATATCGTTTTCTTCCTGACCTCCAACCTTGGCTACCAGGTGATTGTCGAACACGCCG
ATGACCCGGAAACCATGCAGGAAGCCCTCTATCCGGTGCTGGCGGACTTCTTTAAACCTGCTCTGCTGGCGCGCATGGAA
GTGGTGCCTTACCTACCGCTGTCGAAAGAGACGCTCGCTACCATTATTGCCGGGAAACTGGCCCGCCTGGATAACGTGCT
GCGCAGCCGCTTTGGCGCGGACGTGATTATTGGGCCGGAAGTGACGGACGAAATCATGAGCCGCGTCACCCGCGCGGAAA
ACGGCGCGAGGATGCTGGAATCGGTTATCGACGGCGACATGCTGCCGCCGCTCTCGCTGCTGCTGTTGCAGAAAATGGCG
GCCAACACGGCGATTGCCCGGATTCGCCTGTCGGCGGCAGACGGTGCGTTCACGGCAGATGTGGAAGATGCGCTGCCTGA
TGATGCCGTGACACCGCAAACAGAGGATGAAACGGTTTTATGA

Protein sequence :
MIQIDLATLVKRLNPFAKQALEMAASECMSQQASEITVAHVLLQMLAIPRNDVRVIAERTGISAEDLRQALTVESYPGGR
SAEGYPSFSPMLIEWLKESWLLASAQMQHSELRSGVLLLTLLHSPLRYIPPAAARLLTAINRDQLQQDFAAWTKESAESV
DLAGGQTPRATETGDTLLARYAKNMTADARNGRLDPVLCRDYEIDLMIDILCRRRKNNPVVVGDAGVGKSALIEGLALRI
VAGQVPDKLKNTDIMTLDLGALQAGASVKGEFEKRFKGLMAEVIFSPVPVILFIDEAHTLIGAGNQQGGLDISNLLKPAL
ARGELKTIAATTWSEYKKYFEKDAALSHRFQLVKVSEPNAAEATIILRGLLAVYEQSHGVLIDDDALQAAATLSERYLSG
RQLPDKAIDVLDTACARVAINLSSPPKQISALTTLSHQQEAEIRQLERELRIGLRTDTSRMTEVLEQYDETLSALDELEV
AWQQQQTLVQEIIALRQQLLGVAEDDVASLPDADAVEDTPPEAEQDSTDAESADDAGSVQPEETAETVSPVQRLAQLTAE
LDALHNDQLLVSPHVDKKQIAAVIAEWTGVPLNRLSQNEMSVITDLPVWLGGTIKGQDLAIASLHKHLLTARADLRRPGR
PLGAFLLAGPSGVGKTETVLQLAELLYGGRQYLTTINMSEFQEKHTVSRLIGSPPGYVGYGEGGVLTEAIRQKPYSVVLL
DEVEKAHPDVLNLFYQAFDKGEMADGEGRLIDCKNIVFFLTSNLGYQVIVEHADDPETMQEALYPVLADFFKPALLARME
VVPYLPLSKETLATIIAGKLARLDNVLRSRFGADVIIGPEVTDEIMSRVTRAENGARMLESVIDGDMLPPLSLLLLQKMA
ANTAIARIRLSAADGAFTADVEDALPDDAVTPQTEDETVL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 0.0 99
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 0.0 99
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-123 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NRG857_01105 YP_006118586.1 putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2084 Protein 0.0 57
NRG857_01105 YP_006118586.1 putative ATP-dependent Clp proteinase Aec27 ATP-binding chain, with chaperone activity VFG2076 Protein 6e-137 41