Gene Information

Name : NRG857_09910 (NRG857_09910)
Accession : YP_006120337.1
Strain : Escherichia coli NRG 857C
Genome accession: NC_017634
Putative virulence/resistance : Virulence
Product : salicyl-AMP ligase YbtE
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2041530 - 2043107 bp
Length : 1578 bp
Strand : +
Note : COG1021 Peptide arylation enzymes

DNA sequence : 
ATGAATTCTTACTTTGAATCTCTGATTGAACAGTATCCCTTACCCATTGCCGAACAGTTGCGCCACTGGGCGGCCCGTTA
TGCCTCGCGAATTGCCGTCGTTGATGCAAAGGGGTCGTTAACCTACAGCGCGCTTGATGCACAAGTTGACGAACTTGCCG
CAGGTCTGTCATCACTGGGTTTGCGTTCGGGGGAGCATGTAATTGTGCAGCTTCCCAACGACAACGCGTTTGTTACCCTG
CTGTTCGCCTTGTTAAGACTGGGCGTTATCCCCGTGCTGGCGATGCCCTCGCAACGGGCGCTGGATATCGACGCGCTGAT
TGAGCTGGCGCAACCCGTCGCTTACGTTATTCACGGGGAAAACCACGCAGAGCTGGCCCGACAGATGGCGCACAAACACG
CCTGCTTGCGTCATGTTCTGGTCGCTGGAGAGACCGTGAGCGACGATTTTACGCCGCTCTTCTCCCTTCACGGTGAGCGA
CAGGCATGGCCGCAGCCTGATGTTTCCGCCACCGCGTTGTTGTTGCTCTCAGGCGGCACAACCGGCACGCCCAAACTCAT
CCCGCGCCGACATGCCGACTATAGCTATAACTTCAGCGCTTCTGCTGAACTGTGCGGCATCAGCCAACAGAGCGTGTATC
TCGCCGTCCTCCCGGTGGCGCATAACTTTCCGCTGGCCTGCCCCGGTATTCTGGGAACGCTTGCCTGCGGCGGAAAAGTG
GTGCTGACCGACAGCGCCAGCTGTGATGAGGTGATGCCTTTAATCGCGCAGGAAAGAGTGACTCACGTCGCCCTGGTTCC
GGCGCTGGCGCAATTATGGGTGCAGGCCAGGGAGTGGGAAGACAGCGACCTTTCGTCGCTGCGCGTCATTCAGGCAGGCG
GCGCCCGGCTCGACCCGACGCTTGCTGAGCAGGTTATCGCCACCTTTGACTGTACCCTGCAACAGGTTTTCGGTATGGCG
GAAGGCCTGCTCTGTTTTACCCGGCTGGACGATCCGCATGCCACCATTCTCCACAGCCAGGGGCGCCCGTTGTCCCCTCT
GGATGAAATCCGCATCGTTGATCAAGACGAGAACGACGTCGCGCCGGGCGAAACCGGGCAATTGTTAACGCGCGGCCCTT
ATACCATTTCGGGCTATTACCGCGCCCCTGCCCACAACGCGCAGGCCTTTACCGCGCAAGGGTTTTACCGCACAGGCGAC
AATGTCAGGCTGGATGAGGTGGGGAACCTGCACGTTGAGGGACGCATAAAAGAGCAGATCAACCGCGCCGGAGAAAAAAT
AGCCGCGGCTGAAGTGGAATCAGCACTGCTGCGTTTAGCGGAAGTGCAAGATTGCGCGGTGGTCGCCGCGCCGGACACGC
TGCTTGGCGAGCGGATTTGCGCGTTTATCATCGCGCAGCAGGTGCCAACTGACTATCAGCAGTTGCGTCAACAACTGACC
CGTATGGGGCTCAGCGCGTGGAAAATTCCTGACCAAATCGAGTTTCTGGACCACTGGCCGCTCACCGCCGTCGGCAAGAT
AGACAAAAAACACCTGACGGCTCTCGCCGTCGACCGTTATCGCCATTCTGCCCAATAA

Protein sequence : 
MNSYFESLIEQYPLPIAEQLRHWAARYASRIAVVDAKGSLTYSALDAQVDELAAGLSSLGLRSGEHVIVQLPNDNAFVTL
LFALLRLGVIPVLAMPSQRALDIDALIELAQPVAYVIHGENHAELARQMAHKHACLRHVLVAGETVSDDFTPLFSLHGER
QAWPQPDVSATALLLLSGGTTGTPKLIPRRHADYSYNFSASAELCGISQQSVYLAVLPVAHNFPLACPGILGTLACGGKV
VLTDSASCDEVMPLIAQERVTHVALVPALAQLWVQAREWEDSDLSSLRVIQAGGARLDPTLAEQVIATFDCTLQQVFGMA
EGLLCFTRLDDPHATILHSQGRPLSPLDEIRIVDQDENDVAPGETGQLLTRGPYTISGYYRAPAHNAQAFTAQGFYRTGD
NVRLDEVGNLHVEGRIKEQINRAGEKIAAAEVESALLRLAEVQDCAVVAAPDTLLGERICAFIIAQQVPTDYQQLRQQLT
RMGLSAWKIPDQIEFLDHWPLTAVGKIDKKHLTALAVDRYRHSAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
irp5 YP_002346898.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 99
ybtE NP_669710.1 salicyl-AMP ligase Virulence HPI Protein 0.0 99
ybtE NP_993003.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 99
ybtE YP_070120.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 99
ybtE CAA21394.1 - Virulence HPI Protein 0.0 99
ybtE AAA93464.1 yersiniabactin 2,3-dihydoxybenzoate-AMP ligase Virulence HPI Protein 0.0 99
ybtE YP_853079.1 yersiniabactin siderophore biosynthetic protein Virulence PAI IV APEC-O1 Protein 0.0 99
irp5 CAA73130.1 Irp5 protein Virulence HPI Protein 0.0 98
irp5 YP_001006819.1 yersiniabactin siderophore biosynthetic protein Virulence HPI Protein 0.0 98
irp2E YP_005163485.1 siderophore biosynthetic protein Virulence Not named Protein 2e-74 42
irp2E YP_005134497.1 siderophore biosynthetic protein Virulence Not named Protein 1e-74 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
NRG857_09910 YP_006120337.1 salicyl-AMP ligase YbtE VFG0168 Protein 1e-106 51
NRG857_09910 YP_006120337.1 salicyl-AMP ligase YbtE VFG1817 Protein 3e-88 44
NRG857_09910 YP_006120337.1 salicyl-AMP ligase YbtE VFG0932 Protein 2e-80 43