Gene Information

Name : NRG857_09900 (NRG857_09900)
Accession : YP_006120335.1
Strain : Escherichia coli NRG 857C
Genome accession: NC_017634
Putative virulence/resistance : Virulence
Product : Thiazolinyl-S-HMWP1 reductase YbtU
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2039626 - 2040726 bp
Length : 1101 bp
Strand : +
Note : COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis

DNA sequence :
ATGATGCCGTCCGCCTCCCCAAAACAACGCGTACTGATTGTGGGCGCCAAATTTGGCGAAATGTACCTGAATGCCTTTAT
GCAGCCCCCGGAGGGGCTGGAACTGGTCGGCCTGCTGGCGCAGGGAAGCGCCCGTTCAAGAGAGCTGGCTCATGCGTTTG
GCATTCCGCTGTATACCTCGCCGGAACAGATAACCAGGATGCCGGATATCGCCTGTATTGTCGTGCGTTCGACCGTCGCC
GGAGGAACCGGTACGCAGCTTGCCAGACACTTTCTGACGCGCGGCGTACACGTCATTCAGGAGCATCCCCTCCACCCGGA
TGACATCAGTTCCTTACAAACGCTGGCGCAGGAACAGGGCTGCTGCTATTGGGTAAACACGTTTTATCCGCATACGCGCG
CGGGACGCACATGGCTTCGCGATGCGCAGCAGCTGCGTCGCTGCCTGGCTAAGACGCCGCCGGTAGTCCACGCCACCACC
AGCCGACAGTTGCTCTACTCCACTCTGGATTTGTTGTTGCTGGCTCTGGGCGTTGATGCCGCCGCCGTGGAGTGCGACGT
GGTTGGCAGCTTTAGCGATTTTCACTGTCTGAGACTCTTCTGGCCGGAGGGAGAAGCCTGCCTGCTGCTTCAGCGCTATC
TCGATCCTGACGATCCAGATATGCATAGCCTTATCATGCACCGCCTGCTGCTGGGCTGGCCGGAAGGTCATCTTTCGCTG
GAGGCGAGCTACGGCCCCGTCATCTGGTCATCCAGTCTGTATGTCGCAGACCATCAGCAGAACCCCCACAGTCTCTGGCG
CAGACCGGAGATCCTGCGCGATCTGCCGGGTCTGACGCGCAGCGCGGCGCCCCTGAGCTGGCGCGACTGCTGCGAAACCG
TCGGGCCGGAGGGCGTCAGCTGGTTGCTACACCAGTTGCGCAGCAATCTGGCGGGCGAACATCCACCAGCGGCCTGCCAA
AGCGTACATCAGATCGCGTTATCACGTTTATGGCAGCAGGTTTTACGTAAGACCGGCAATGCGGAGATCAGACGCCTGAC
GCCGCCGCACCACGACCGGTTAGCCGGTTTCTACAACGATGATGATAAGGAGGCGCTGTGA

Protein sequence :
MMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSARSRELAHAFGIPLYTSPEQITRMPDIACIVVRSTVA
GGTGTQLARHFLTRGVHVIQEHPLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLRDAQQLRRCLAKTPPVVHATT
SRQLLYSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDDPDMHSLIMHRLLLGWPEGHLSL
EASYGPVIWSSSLYVADHQQNPHSLWRRPEILRDLPGLTRSAAPLSWRDCCETVGPEGVSWLLHQLRSNLAGEHPPAACQ
SVHQIALSRLWQQVLRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtU NP_669708.2 thiazolinyl-S-HMWP1 reductase Virulence HPI Protein 7e-160 99
ybtU NP_993005.2 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 7e-160 99
ybtU YP_070122.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 7e-160 99
ybtU CAA21392.1 - Virulence HPI Protein 3e-159 99
ybtU YP_853077.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-159 99
irp3 YP_002346900.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 7e-160 99
irp3 YP_001006817.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 3e-160 97
irp3 CAA73128.1 Irp3 protein Virulence HPI Protein 9e-160 97
nrpU YP_002152319.1 siderophore biosynthetic protein Virulence Not named Protein 5e-62 43