Gene Information

Name : flu (ETEC_4462)
Accession : YP_006118001.1
Strain : Escherichia coli ETEC H10407
Genome accession: NC_017633
Putative virulence/resistance : Virulence
Product : putative antigen 43 precursor (fluffing protein)
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4841315 - 4844284 bp
Length : 2970 bp
Strand : -
Note : -

DNA sequence :
ATGAAGGGTGAGAGCGTTTACGCCCGGGACGTATCGCTGTGCCCGATAACTCTGTTTTGTACCTGCCGGTATCCACTTTT
GTGGGTACCGGCTTTTTTATTCACCCTCTGTAAGGAAAAGCTGATGAAACGACATCTGAACACCAGCTACAGGCTGGTAT
GGAATCACATTACGGGCACCCTGGTGGTGGCCTCCGAACTGGCCCGCTCACGGGGAAAACGCACCGGTGTGGCAGTTGCG
CTGTCTCTTGCCACCGCCACTTCAGTCCCGGCCCTGGCTGCTGACAGTGTTGTACAGGCGGGAGAAACCGTGAGCGGCGG
AACACTGGAAAATCATGACAACCAGATTGTCTTCGGTACGACCAACGGAATAACCATCAGTACCGGGCTGGAGTATGGGC
CGGATAACGAGGCCAATACTGGCGGGCAATGGGTACAGGATGGCGGCACAGCCAGTAATACCACCATCAGCAGCGGTGGG
CTCCAGTTTGTAGGTGCCGGGGGAAAGGCTACAGACACAATAATCAATGAAGGAGGCGGACAAAGTCTGAAGGGACTGGC
ACTGAACACCACGCTGAATGGTGGCGAGCAGTGGATGCATGAAGGTGCGATAGCCACAGGAACCGTCATTAATGATAAGG
GCTGGCAGGTCGTCAAACCCGGCGCAGTGGCAACAGACACCGTTGTGAATACCGGCGCGGAAGGAGGACCGGATGCAGAA
AATGCTGATACCGGACAGTTTGTTCGCGGAGATGCCGTACGTACCACCATCAATAAAAATGGTCGTCAGATTGTGGTAGC
CACCGGAGTGGCAAACACCACGGTGGTTTATGCCGGCGGCGACCAGACTGTGCATGGCTACGCGCTGGATACCACACTGA
ACGGCGGTAACCAGTATGTGCACAACGGCGGTACAGCGTCCGACACTGTTGTGAACAGTGACGGCTGGCAGATTATCAAG
GAGGGTGGTCTGGCGGATTTCACCACCGTTAACCAGAAAGGCAAACTGCAGGTGAACGCCGGTGGTACAGCCACGAATGT
CACCCTGAAGCAGGGCGGCGCACTGGTCACCAGTACAGCAGCAACTGTTCTTGGCAGCAACCGTCTGGGGAATTTCACGG
TGGAAAACGGTAAGGCTGACGGTGTTGTTCTGGAGTCCGGTGGTCGCCTGGATGTACTGGAGGGCCATTCAGCCTGGAAA
ACACTGGTGGATGACGGCGGTATCCTGGCAGTGTCTGCCGGTGGTAAGGCAACAGATGTCACCATGACATCCGGTGGTGC
CCTGATTGCAGACAGTGGTGCCACTGTTGAGGGGACCAATGCCAGCGGTAAGTTCAGTATTGATGGTATATCCGGTCAGG
CCAGCGGCCTGCTGCTGGAAAATGGCGGCAGCTTTACGGTTAATGCCGGGGGACAGGCTGGCAACACCACTGTCGGACAT
CGTGGAACACTGACGCTGGCTGCCGGGGGAAGTCTGAGTGGAAGAACACAGCTCAGTAAAGGCGCCAGTATGGTACTGAA
TGGTGATGTGGTCAGTACCGGCGATATTGTTAACGCAGGAGAGATTCACTTTGATAATCAGACGACACAGGATGCCGTAC
TGAGCCGTGCTGTTGCAAAAAGTAACTCCCCGGTAACGTTCCATAAACTGACCACCACGAACCTCACCGGCCAGGGTGGC
ACCATCAATATGCGTGTCAGCCTTGATGGCAGTAATGCCTCTGACCAGCTGGTGATTAATGGTGGTCAGGCAACCGGCAA
AACCTGGCTTGCGTTTACAAATGTCGGAAACAGTAACCTCGGGGTGGCAACCTCCGGACAGGGTATCCGGGTTGTGGATG
CACAGAATGGCGCCACCACAGAAGAAGGTGCGTTTGCCCTGAGTCGCCCGCTTCAGGCCGGCGCCTTTAACTACACCCTG
AACCGTGACAGCGATGAAGACTGGTACCTGCGCAGTGAAAATGCTTATCGTGCTGAAGTCCCCCTGTATACATCCATGCT
GACACAGGCAATGGACTATGACCGGATTCTGGCAGGCTCCCGCAGCCATCAGACCGGTGTAAACGGTGAAAATAACAGCG
TCCGTCTCAGCATTCAGGGCGGTCATCTCGGTCACGATAACAACGGCGGTATTGCCCGTGGAGCCACGCCGGAAAGCAGC
GGCAGCTATGGCTTCGTCCGTCTGGAGGGTGACCTGCTGAGAACAGAGGTTGCCGGTATGTCTGTGACCGCGGGGGTATA
TGGTGCTGCTGGCCATTCTTCCGTTGATGTTAAGGATGATGACGGCTCCCGCGCCGGCACGGTCCGGGATGATGCCGGCA
GTCTGGGCGGATACCTGAATCTGGTACACACGTCCTCCGGCCTGTGGGCTGACATTGTGGCACAGGGAACCCGCCACAGC
ATGAAAGCGTCAACGGACAATAACGACTTCCGCGCCCGGGGTTGGGGCTGGCTGGGTTCACTGGAAACCGGTCTGCCCTT
CAGTATCACTGACAACCTGATGCTGGAGCCACAACTGCAGTATACCTGGCAGGGACTTTCCCTGGATGACGGTAAGGACA
ACGCCGGTTATGTGAAGTTCGGGCATGGCAGTGCACAACATGTGCGTGCCGGTTTCCGTCTGGGCAGCCACAACGATATG
ACCTTTGGCGAAGGCACCTCATCCCGTGCCCCCCTGCGTGACAGTGCAAAACACAGTATGCGTGAACTGCCGGTGAACTG
GTGGGTACAGCCTTCTGTTATCCGCACCTTCAGCTCCCGGGGAGACATGAGCATGGGTACAGCCGCAGCCGGCAGTAACA
TGACGTTCTCACCGTCCCGGAATGGCACGTCACTGGACCTGCAGGCCGGACTGGAAGCCCGTGTCCGGGAAAATATCACT
CTGGGCGTTCAGGCCGGTTATGCCCACAGCGTCATCGGCAGCAGCGCTGAAGGGTATAACGGTCAGGCCACACTGAATGT
GACCTTCTGA

Protein sequence :
MKGESVYARDVSLCPITLFCTCRYPLLWVPAFLFTLCKEKLMKRHLNTSYRLVWNHITGTLVVASELARSRGKRTGVAVA
LSLATATSVPALAADSVVQAGETVSGGTLENHDNQIVFGTTNGITISTGLEYGPDNEANTGGQWVQDGGTASNTTISSGG
LQFVGAGGKATDTIINEGGGQSLKGLALNTTLNGGEQWMHEGAIATGTVINDKGWQVVKPGAVATDTVVNTGAEGGPDAE
NADTGQFVRGDAVRTTINKNGRQIVVATGVANTTVVYAGGDQTVHGYALDTTLNGGNQYVHNGGTASDTVVNSDGWQIIK
EGGLADFTTVNQKGKLQVNAGGTATNVTLKQGGALVTSTAATVLGSNRLGNFTVENGKADGVVLESGGRLDVLEGHSAWK
TLVDDGGILAVSAGGKATDVTMTSGGALIADSGATVEGTNASGKFSIDGISGQASGLLLENGGSFTVNAGGQAGNTTVGH
RGTLTLAAGGSLSGRTQLSKGASMVLNGDVVSTGDIVNAGEIHFDNQTTQDAVLSRAVAKSNSPVTFHKLTTTNLTGQGG
TINMRVSLDGSNASDQLVINGGQATGKTWLAFTNVGNSNLGVATSGQGIRVVDAQNGATTEEGAFALSRPLQAGAFNYTL
NRDSDEDWYLRSENAYRAEVPLYTSMLTQAMDYDRILAGSRSHQTGVNGENNSVRLSIQGGHLGHDNNGGIARGATPESS
GSYGFVRLEGDLLRTEVAGMSVTAGVYGAAGHSSVDVKDDDGSRAGTVRDDAGSLGGYLNLVHTSSGLWADIVAQGTRHS
MKASTDNNDFRARGWGWLGSLETGLPFSITDNLMLEPQLQYTWQGLSLDDGKDNAGYVKFGHGSAQHVRAGFRLGSHNDM
TFGEGTSSRAPLRDSAKHSMRELPVNWWVQPSVIRTFSSRGDMSMGTAAAGSNMTFSPSRNGTSLDLQAGLEARVRENIT
LGVQAGYAHSVIGSSAEGYNGQATLNVTF

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAE85197.1 antigen43 protein orthologue Not tested PAI V 536 Protein 0.0 93
unnamed AAL08472.1 putative autotransporter Not tested SRL Protein 0.0 92
Z1211 NP_286746.1 adhesin Not tested TAI Protein 0.0 88
Z1651 NP_287154.1 adhesin Not tested TAI Protein 0.0 88
S3195 NP_838479.1 outer membrane fluffing protein Not tested SHI-1 Protein 0.0 64
aec67 AAW51750.1 Aec67 Not tested AGI-3 Protein 0.0 64
aidA ADD91708.1 AidA Not tested PAI-I AL862 Protein 0.0 61
sap AAK00474.1 Sap Not tested SHI-1 Protein 0.0 57
unnamed CAD66200.1 hypothetical protein Virulence PAI III 536 Protein 0.0 57
SF2991 NP_708765.1 outer membrane fluffing protein Not tested SHI-1 Protein 0.0 57
flu CAI43838.1 antigen 43 Not tested LEE Protein 0.0 57

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
flu YP_006118001.1 putative antigen 43 precursor (fluffing protein) VFG1063 Protein 0.0 92
flu YP_006118001.1 putative antigen 43 precursor (fluffing protein) VFG1675 Protein 0.0 57
flu YP_006118001.1 putative antigen 43 precursor (fluffing protein) VFG0655 Protein 0.0 57