Gene Information

Name : mrfC (ETEC_2473)
Accession : YP_006116028.1
Strain : Escherichia coli ETEC H10407
Genome accession: NC_017633
Putative virulence/resistance : Virulence
Product : putative outer membrane fimbrial usher protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 2679519 - 2682164 bp
Length : 2646 bp
Strand : -
Note : -

DNA sequence :
ATGCCTGACCATTCTCTTTTTCGATTACGGATTCTTCCGTGGTGCATTGCGCTGGCAATGTCAGGGAGTTATAGCAGTGT
CTGGGCTGAAGACGACATTCAGTTTGATTCCCGTTTTCTGGAATTAAAAGGCGACACAAAAATTGATCTGAAGCGTTTTT
CCAGCCAGGGGTATGTTGAGCCCGGAAAATACAATTTACAGGTTCAACTAAATAAACAGCCATTGGCGGAAGAGTACGAT
ATTTACTGGTATGCTGGTGAAGATGACGTTAGCAAAAGCTATGCTTGTCTGACACCGGAACTGGTGGCGCAGTTTGGTTT
AAAAGAAGACGTGGCGAAAAATCTGCAATGGAGCCACGATGGTAAATGCCTGAAGCCCGGTCAACTGGAAGGCATGGAAA
TTAAGGCTGATTTAAGCCAGTCCGCATTAGTCATTTCACTACCGCAGGCTTACCTCGAATATACCTGGCCCGACTGGGAT
CCACCTTCTCGTTGGGATGATGGCATCTCCGGGATCATTGCGGACTACAGCATCACTGCGCAAACACGACACGAAGAAAA
TGGCGGCGATGACAGTAACGAGATCAGCGGCAACGGGACGGTCGGGGTTAACCTGGGGCCATGGCGTATGCGCGCTGACT
GGCAGACCAACTATCAACATACGCGCAGTAATGATGATGACGATGAATTTGGCGGCGATGACACACAAAAAAAATGGGAG
TGGAGTCGCTATTATGCCTGGCGGGCGTTACCGTCATTAAAAGCCAAACTGGCGCTGGGCGAAGATTACCTCAATTCCGA
TATTTTCGACGGTTTTAATTATGTTGGTGGCAGTGTCAGCACTGACGATCAAATGTTGCCTCCCAACCTGCGCGGCTACG
CGCCAGACATTTCCGGCGTGGCACACACCACAGCAAAAGTGACCGTCAGCCAGATGGGGCGTGTGATTTACGAAACGCAG
GTTCCGGCTGGACCGTTTCGTATTCAGGATCTTGGTGATTCCGTCTCCGGTACGTTGCATATTCGCATTGAAGAACAGAA
CGGCCAGGTGCAGGAATATGACATCAGCACCGCCTCGATGCCATACCTCACTCGCCCAGGCCAGGTTCGCTATAAGATCA
TGATGGGACGTCCGCAAGAGTGGGGCCACCATGTCGAGGGGGGATTTTTCTCTGGTGCTGAAGCCTCCTGGGGCATCGCT
AACGGCTGGTCGTTATATGGCGGTGCGCTGGGTGATGAAAACTATCAGTCTGCGGCGCTGGGCGTCGGTCGCGATTTGTC
TACCTTCGGCGCGGTCGCGTTTGATGTTACTCATTCGCATACCAAACTGGATAAAGACACCGCTTATGGCAAAGGTTCGC
TGGACGGTAACTCCTTCCGTGTGAGTTATTCCAAAGACTTTGACCAGCTCAACAGCCGCGTCACTTTCGCTGGATATCGC
TTCTCGGAAGAGAACCTTATGACCATGAGCGAGTATCTGGATGCCAGTGACAGCGAAATGGTCCGTACGGGCAACGACAA
AGAGATGTACACCGCCACTTATAACCAGAACTTCCGCGATGCGGGTGTTTCGGTTTATCTCAACTATACCCGCCATACCT
ACTGGGATCGTGAGGAGCAGACAAACTACAACATCATGCTCTCCCACTATTTCAATATGGGCAGCATTCGTAATATGAGC
GTTTCCCTGACTGGCTACCGCTACGAGTATGACAACCGGGCGGATAAGGGCATGTACATTTCGCTCAGTATGCCGTGGGG
CGACAACAGTACCGTTAGCTATAACGGCAACTATGGCAGTGGGACGGACAGCAGCCAGGTCGGTTATTTTAGCCGTGTCG
ATGACGCGACTCACTATCAGTTGAACATCGGCACCAGTGACAAACACACCAGCGTTGATGGCTACTACAGCCATGATGGT
TCGCTGGCGCAGGTTGACCTCAGTGCGAACTACCATGAAGGGCAATACACCTCTGCGGGCTTGTCGTTACAGGGCGGCGC
AACGCTTACTACCCACGGCGGCGCACTTCACCGTACCCAGAATATGGGCGGGACACGCCTGCTGATTGATGCCGATGGCG
TTGCCGATGTTCCGGTGGAAGGTAACGGGGCTGCTGTTTATACCAATATGTTTGGTAAAGCCGTCGTTTCTGACGTTAAC
AATTATTATCGCAATCAGGCGTATATCGACCTCAACAAATTGCCGGAAAACGCCGAAGCAACCCAGTCGGTGGTGCAAGC
CACGCTAACTGAAGGAGCCATTGGCTACCGCAAATTTGCCGTCATCAGTGGTCAAAAAGCGATGGCGGTGCTGCGTTTAC
AAGATGGCAGCCATCCACCGTTTGGCGCAGAAGTAAAAAATGATAACGAGCAGACAGTGGGCCTTGTCGATGATGACGGT
AGTGTCTATCTGGCTGGGGTGAAACCTGGCGAACATATGAGTGTGTTCTGGAGTGGTGTTGCGCATTGCGATATCAACCT
GCCGGACCCGCTGCCTGCCGATCTGTTTAACGGCTTGTTACTGCCATGCCAGCATAAAGGCAACGTCGCGCCGGTTGTTC
CTGATGACATAAAGCCTGTCATTCAGGAGCAGACGCAACAGGTGACACCCACCGATCCCCCTGTTTCTGTTTCAGCTAAC
CAATAA

Protein sequence :
MPDHSLFRLRILPWCIALAMSGSYSSVWAEDDIQFDSRFLELKGDTKIDLKRFSSQGYVEPGKYNLQVQLNKQPLAEEYD
IYWYAGEDDVSKSYACLTPELVAQFGLKEDVAKNLQWSHDGKCLKPGQLEGMEIKADLSQSALVISLPQAYLEYTWPDWD
PPSRWDDGISGIIADYSITAQTRHEENGGDDSNEISGNGTVGVNLGPWRMRADWQTNYQHTRSNDDDDEFGGDDTQKKWE
WSRYYAWRALPSLKAKLALGEDYLNSDIFDGFNYVGGSVSTDDQMLPPNLRGYAPDISGVAHTTAKVTVSQMGRVIYETQ
VPAGPFRIQDLGDSVSGTLHIRIEEQNGQVQEYDISTASMPYLTRPGQVRYKIMMGRPQEWGHHVEGGFFSGAEASWGIA
NGWSLYGGALGDENYQSAALGVGRDLSTFGAVAFDVTHSHTKLDKDTAYGKGSLDGNSFRVSYSKDFDQLNSRVTFAGYR
FSEENLMTMSEYLDASDSEMVRTGNDKEMYTATYNQNFRDAGVSVYLNYTRHTYWDREEQTNYNIMLSHYFNMGSIRNMS
VSLTGYRYEYDNRADKGMYISLSMPWGDNSTVSYNGNYGSGTDSSQVGYFSRVDDATHYQLNIGTSDKHTSVDGYYSHDG
SLAQVDLSANYHEGQYTSAGLSLQGGATLTTHGGALHRTQNMGGTRLLIDADGVADVPVEGNGAAVYTNMFGKAVVSDVN
NYYRNQAYIDLNKLPENAEATQSVVQATLTEGAIGYRKFAVISGQKAMAVLRLQDGSHPPFGAEVKNDNEQTVGLVDDDG
SVYLAGVKPGEHMSVFWSGVAHCDINLPDPLPADLFNGLLLPCQHKGNVAPVVPDDIKPVIQEQTQQVTPTDPPVSVSAN
Q

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 4e-144 44
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 1e-142 44
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 8e-143 44
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 5e-144 44
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 6e-144 44
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 6e-144 44
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 1e-149 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
mrfC YP_006116028.1 putative outer membrane fimbrial usher protein VFG1548 Protein 2e-144 44
mrfC YP_006116028.1 putative outer membrane fimbrial usher protein VFG0884 Protein 2e-144 44
mrfC YP_006116028.1 putative outer membrane fimbrial usher protein VFG0895 Protein 2e-144 44