Gene Information

Name : UM146_21870 (UM146_21870)
Accession : YP_006113214.1
Strain : Escherichia coli UM146
Genome accession: NC_017632
Putative virulence/resistance : Virulence
Product : DNA-binding response regulator
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4572850 - 4573569 bp
Length : 720 bp
Strand : +
Note : COG0745 Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

DNA sequence : 
ATGAATAACGTAAAAAAAATACTGCTGATGGAAGATGATTATGATATTGCAGCTCTGTTGCGGCTTAATCTGCAGGATGA
AGGGTATCAGATAGTTCATGAAGCGGATGGCGCCAGAGCTCGTTTATTACTAGACAAGCAGACCTGGGATGCCGTAATAC
TTGATCTTATGCTGCCTAATGTTAATGGGCTGGAGATTTGCCGTTATATCCGTCAGATGACCCGTTATCTGCCTGTGATT
ATCATCAGTGCCCGTACCAGCGAAACCCACCGCGTCCTGGGACTGGAAATGGGGGCTGATGACTATCTACCGAAACCCTT
TTCCATTCCTGAGCTGATTGCCCGCATCAAAGCGTTGTTTCGTCGTCAGGAAGCCATGGGGCAAAATATTCTCCTGGCAG
GTGGACTGATTTGCTGTCACGGTCTGTGCATCAATCCATTTTCACGTGAAGTTCATTTGCATAATAAACAGGTTGATCTT
ACCCCACGCGAGTTTGATCTGCTGCTCTGGTTTGCACGTCATCCTGGCGAAGTTTTTTCCCGTCTTTCACTGCTGGATAA
TGTCTGGGGGTATCAGCATGAAGGATATGAGCATACAGTCAACACGCATATCAACCGTCTTCGTGCCAAAATTGAACAGG
ATGCAGCAGAGCCAAAGATGATCCAGACCGTCTGGGGAAAAGGGTATAGGTTTTCAGTTGACAATGCAGGAATGCGATAA

Protein sequence : 
MNNVKKILLMEDDYDIAALLRLNLQDEGYQIVHEADGARARLLLDKQTWDAVILDLMLPNVNGLEICRYIRQMTRYLPVI
IISARTSETHRVLGLEMGADDYLPKPFSIPELIARIKALFRRQEAMGQNILLAGGLICCHGLCINPFSREVHLHNKQVDL
TPREFDLLLWFARHPGEVFSRLSLLDNVWGYQHEGYEHTVNTHINRLRAKIEQDAAEPKMIQTVWGKGYRFSVDNAGMR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 3e-111 99
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 2e-111 99

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UM146_21870 YP_006113214.1 DNA-binding response regulator AE015929.1.gene1106. Protein 3e-27 42
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_012469.1.7685629. Protein 6e-37 42
UM146_21870 YP_006113214.1 DNA-binding response regulator HE999704.1.gene2815. Protein 1e-41 42
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_013450.8614146.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_002951.3238224.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_007793.3914065.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_002758.1121390.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_010079.5776364.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_002952.2859858.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_007622.3794948.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator NC_003923.1003417.p0 Protein 2e-32 41
UM146_21870 YP_006113214.1 DNA-binding response regulator HE999704.1.gene1528. Protein 2e-31 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UM146_21870 YP_006113214.1 DNA-binding response regulator VFG1563 Protein 1e-111 99
UM146_21870 YP_006113214.1 DNA-binding response regulator VFG1702 Protein 8e-112 99