Gene Information

Name : UM146_21835 (UM146_21835)
Accession : YP_006113207.1
Strain : Escherichia coli UM146
Genome accession: NC_017632
Putative virulence/resistance : Virulence
Product : hemolysin D
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4562640 - 4564076 bp
Length : 1437 bp
Strand : -
Note : COG0845 Membrane-fusion protein

DNA sequence :
ATGAAAACATGGTTAATGGGGTTCAGCGAGTTCCTGTTGCGCTATAAACTTGTCTGGAGTGAAACATGGAAAATCCGGAA
GCAATTAGATACTCCGGTACGTGAAAAGGACGAAAATGAATTCTTACCCGCTCATCTGGAATTAATTGAAACGCCGGTAT
CCAGACGGCCGCGTCTGGTTGCTTATTTTATTATGGGGTTTCTGGTTATTGCTGTCATTTTATCTGTTTTAGGTCAGGTG
GAAATTGTTGCCACTGCAAATGGGAAATTAACACTAAGTGGGCGTAGCAAAGAAATTAAACCTATTGAAAACTCAATAGT
TAAAGAAATTATCGTAAAAGAAGGAGAGTCAGTCCGGAAAGGGGATGTGTTATTAAAGCTTACAGCACTGGGAGCTGAAG
CTGATACGTTAAAAACACAGTCATCACTGTTACAGACCAGGCTGGAACAAACTCGGTATCAAATTCTGAGCAGGTCAATT
GAATTAAATAAACTACCTGAACTGAAGCTTCCTGATGAGCCTTATTTTCAGAATGTATCTGAAGAGGAAGTACTGCGTTT
AACTTCTTTGATAAAAGAACAGTTTTCCACATGGCAAAATCAGAAGTATCAAAAAGAACTGAATCTGGATAAGAAAAGAG
CAGAGCGATTAACAATACTTGCCCGTATAAACCGTTATGAAAATTTATCGAGAGTTGAAAAAAGCCGTCTGGATGATTTC
AGGAGTTTATTGCATAAACAGGCAATTGCAAAACATGCTGTACTTGAGCAGGAGAATAAATATGTCGAGGCAGCAAATGA
ATTACGGGTTTATAAATCGCAACTGGAGCAAATTGAGAGTGAGATATTGTCTGCAAAAGAAGAATATCAGCTTGTCACGC
AGCTTTTTAAAAATGAAATTTTAGACAAGCTAAGACAAACAACAGACAGCATTGAGTTATTAACTCTGGAGTTAGAGAAA
AATGAAGAGCGTCAACAGGCTTCAGTAATCAGGGCCCCTGTTTCGGGAAAAGTTCAGCAACTGAAGGTTCATACTGAAGG
TGGGGTTGTTACAACAGCGGAAACACTGATGGTCATCGTTCCGGAAGATGACACGCTGGAGGTTACTGCTCTGGTACAAA
ATAAAGATATTGGTTTTATTAACGTCGGGCAGAATGCCATCATTAAAGTGGAGGCCTTTCCTTACACCCGATATGGTTAT
CTGGTGGGTAAGGTGAAAAATATAAATTTAGATGCAATAGAAGACCAGAAACTGGGACTCGTTTTTAATGTCATTGTTTC
TGTTGAAGAGAATGATTTGTCAACCGGGAATAAGCACATTCCATTAAGCTCGGGTATGGCTGTCACTGCAGAAATAAAGA
CTGGAATGCGAAGCGTAATCAGCTATCTTCTTAGTCCTCTGGAAGAGTCTGTAACAGAAAGTTTACATGAGCGTTAA

Protein sequence :
MKTWLMGFSEFLLRYKLVWSETWKIRKQLDTPVREKDENEFLPAHLELIETPVSRRPRLVAYFIMGFLVIAVILSVLGQV
EIVATANGKLTLSGRSKEIKPIENSIVKEIIVKEGESVRKGDVLLKLTALGAEADTLKTQSSLLQTRLEQTRYQILSRSI
ELNKLPELKLPDEPYFQNVSEEEVLRLTSLIKEQFSTWQNQKYQKELNLDKKRAERLTILARINRYENLSRVEKSRLDDF
RSLLHKQAIAKHAVLEQENKYVEAANELRVYKSQLEQIESEILSAKEEYQLVTQLFKNEILDKLRQTTDSIELLTLELEK
NEERQQASVIRAPVSGKVQQLKVHTEGGVVTTAETLMVIVPEDDTLEVTALVQNKDIGFINVGQNAIIKVEAFPYTRYGY
LVGKVKNINLDAIEDQKLGLVFNVIVSVEENDLSTGNKHIPLSSGMAVTAEIKTGMRSVISYLLSPLEESVTESLHER

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hlyD NP_755449.1 hemolysin D Virulence PAI I CFT073 Protein 0.0 99
hlyD AAC61717.1 chromosomal hemolysin D Virulence PAI I CFT073 Protein 0.0 99
hlyD CAD42037.1 HlyD protein Virulence PAI II 536 Protein 0.0 99
hlyD CAD33761.1 Hemolysin D Virulence PAI I 536 Protein 0.0 99

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UM146_21835 YP_006113207.1 hemolysin D VFG0908 Protein 0.0 99
UM146_21835 YP_006113207.1 hemolysin D VFG1502 Protein 0.0 99
UM146_21835 YP_006113207.1 hemolysin D VFG1556 Protein 0.0 99
UM146_21835 YP_006113207.1 hemolysin D VFG0843 Protein 4e-120 57