Gene Information

Name : UM146_09525 (UM146_09525)
Accession : YP_006110800.1
Strain : Escherichia coli UM146
Genome accession: NC_017632
Putative virulence/resistance : Virulence
Product : outer membrane usher protein FimD
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1992852 - 1995503 bp
Length : 2652 bp
Strand : +
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGACAGCCTTTCGTGCCGCATTTAAGGCATATCGTATGCATCAGGTGTTAATACTGCCTCGCTTTGCACGGCTTACCTT
TGCCCTTGGCTTAGCAACTGCGGTTTTTCCCGTTGACGCAGAGTATTATTTTAATCCACGGTTTTTAAGCAATGACCTTG
CTGAATCTGTCGATTTATCTGCCTTTACTAAGGGACGCGAGGCCCCACCTGGTACATATCGGGTCGACATTTATTTGAAC
GACGAATTTATGGCTAGTCGGGATATTACTTTTATTGCAGATGATAATAACGCAGATCTCATCCCATGCCTGAGTACAGA
CCTTCTTGTCAGTCTTGGCATAAAAAAATCAGCATTATTAGACAACAAGGAACATTCGGCAGATAAACATGTGCCGGACA
ACAGCGCATGCACACCACTTCAGGATCGTTTGGCTGATGCATCATCTGAGTTTGATGTTGGTCAGCAACATCTGTCACTC
TCCGTTCCGCAAATATATGTCGGCAGAATGGCTCACGGCTATGTTTCTCCTGATCTGTGGGAAGAAGGAATAAATGCAGG
GCTACTAAACTATAGTTTTAATGGTAATTCTATTAATAACCGTAGTAACCATAATGCAGGAAAATCCAACTATGCATATT
TGAATTTACAGAGTGGCATCAACATTGGTAGTTGGCGACTGCGCGATAACTCAACGTGGAGTTATAACAGTGGGAGTAGC
AATTCATCTGACAGCAATAAATGGCAGCATATCAATACGTCGGCTGAACGTGACATTATTCCGTTACGCTCACGGTTAAC
AGTGGGTGATAGTTATACCGATGGCGATATTTTTGACAGTGTGAACTTTCGTGGCCTTAAAATAAATTCAACAGAAGCGA
TGTTGCCCGATAGCCAACATGGTTTCGCTCCGGTGATTCATGGTATTGCTCGTGGCACCGCACAAGTGAGTGTAAAACAG
AATGGATACGATGTTTATCAGACTACTGTCCCACCCGGCCCTTTTACTATTGATGATATCAACTCTGCGGCCAATGGTGG
TAATCTGCAAGTAACCATAAAAGAGGCAGACGGCAGTATTCAGACATTATATGTTCCTTATTCGTCTGTTCCGGTTCTCC
AACGTGCTGGATATACGCGTTATGCACTTGCCATGGGGGAATATCGTAGTGGAAATAACCTGCAAAGCACCCCCAAGTTC
GTACAAGCAAGCTTGATGCATGGTCTGAAAGGAAACTGGACACCTTATGGCGGAATGCAAATTGCAGAAGATTATCAGGC
CTTCAACCTTGGTATTGGTAAAGATTTAGGACTTTTTGGTGCCTTTTCTTTCGATATTACGCAGGCCAATACGACACTTG
CAGATGACACCCGTCACAGCGGACAATCGGTTAAATTCGTCTACAGCAAATCCTTCTACCAGACGGGAACCAATATCCAG
GTCGCAGGATATCGCTATTCTACGCAAGGTTTTTATAACTTATCCGACAGTGCATACAGTCGAATGAGTGGTTACACCGT
CAAGCCTCCTACCGGAGACACCAGTGAGCAGACACTATTTATTGATTATTTTAATCTGTTCTACAGTAAGCGTGGTCAGG
AACAAATAAGCATCTCTCAGCAGCTTGGAAATTATGGTACGACATTTTTCAGTGCCAGTCGCCAAAGTTACTGGAACACG
TCACGCAGCGACCAGCAAATATCATTTGGATTAAATGTGCCGTTTGGTGATATTACGACTTCGCTGAATTACAGCTATTC
CAATAATATATGGCAAAACGATCGGGATCATTTACTCGCTTTTACGCTTAATGTTCCCTTTAGTCATTGGATGCGTACAG
ACAGTCAGTCGGCATTTCATAATTCAAACGCCAGTTACAGTATGTCAAACGATTTGAAAGGCGGCATGACCAACCTATCA
GGGGTTTATGGCACTCTGCTACCGGATAATAACCTGAATTATAGTGTTCAGGTCGGTAACACCCAAGGGGGTAATACATC
GTCTGGCACCAGTGGTTACAGTTCTCTTAATTATCGTGGTGCTTACGGTAATACGAATGTCGGTTACAGTCGGAGTGGTG
ACAGCAGCCAGATTTATTACGGAATGAGTGGTGGGATTATTGCTCATGCTGATGGCATCACCTTTGGACAGCCGCTGGGC
GACACAATGGTTCTGGTTAAGGCTCCTGGCGCTGATAATGTCAAAATAGAGAACCAGACCGGAATTCATACCGACTGGCG
TGGCTATGCCATATTACCATTTGCGACAGAATATAGAGAAAATCGTGTCGCTCTTAACGCGAATTCCCTTGCAGATAATG
TTGAACTGGATGAAACCGTAGTCACTGTCATCCCAACTCACGGTGCTATTGCCAGAGCAACATTTAATGCACAAATCGGC
GGGAAAGTATTAATGACGTTGAAGTACGGTAATAAAAGCGTTCCATTCGGTGCAATTGTCACTCACGGAGAGAATAAAAA
TGGCAGCATTGTCGCGGAAAATGGTCAGGTTTATCTGACTGGACTTCCACAGTCAGGGAAATTACAGGTTTCATGGGGCA
AAGATAAAAACTCAAACTGTATTGTCGATTACAAGCTTCCTGTAGTCTCTCCTGGAACCTTGCTGAACCAGCAGACAGCA
ATCTGTCGCTAA

Protein sequence :
MTAFRAAFKAYRMHQVLILPRFARLTFALGLATAVFPVDAEYYFNPRFLSNDLAESVDLSAFTKGREAPPGTYRVDIYLN
DEFMASRDITFIADDNNADLIPCLSTDLLVSLGIKKSALLDNKEHSADKHVPDNSACTPLQDRLADASSEFDVGQQHLSL
SVPQIYVGRMAHGYVSPDLWEEGINAGLLNYSFNGNSINNRSNHNAGKSNYAYLNLQSGINIGSWRLRDNSTWSYNSGSS
NSSDSNKWQHINTSAERDIIPLRSRLTVGDSYTDGDIFDSVNFRGLKINSTEAMLPDSQHGFAPVIHGIARGTAQVSVKQ
NGYDVYQTTVPPGPFTIDDINSAANGGNLQVTIKEADGSIQTLYVPYSSVPVLQRAGYTRYALAMGEYRSGNNLQSTPKF
VQASLMHGLKGNWTPYGGMQIAEDYQAFNLGIGKDLGLFGAFSFDITQANTTLADDTRHSGQSVKFVYSKSFYQTGTNIQ
VAGYRYSTQGFYNLSDSAYSRMSGYTVKPPTGDTSEQTLFIDYFNLFYSKRGQEQISISQQLGNYGTTFFSASRQSYWNT
SRSDQQISFGLNVPFGDITTSLNYSYSNNIWQNDRDHLLAFTLNVPFSHWMRTDSQSAFHNSNASYSMSNDLKGGMTNLS
GVYGTLLPDNNLNYSVQVGNTQGGNTSSGTSGYSSLNYRGAYGNTNVGYSRSGDSSQIYYGMSGGIIAHADGITFGQPLG
DTMVLVKAPGADNVKIENQTGIHTDWRGYAILPFATEYRENRVALNANSLADNVELDETVVTVIPTHGAIARATFNAQIG
GKVLMTLKYGNKSVPFGAIVTHGENKNGSIVAENGQVYLTGLPQSGKLQVSWGKDKNSNCIVDYKLPVVSPGTLLNQQTA
ICR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
fim2D AFH78429.1 putative fimbrial usher protein Virulence KpGI-5 Protein 0.0 57
sfaF CAC16953.2 SfaF protein Virulence PAI III 536 Protein 0.0 54

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UM146_09525 YP_006110800.1 outer membrane usher protein FimD VFG0876 Protein 0.0 58
UM146_09525 YP_006110800.1 outer membrane usher protein FimD VFG1645 Protein 0.0 54
UM146_09525 YP_006110800.1 outer membrane usher protein FimD VFG0912 Protein 0.0 54
UM146_09525 YP_006110800.1 outer membrane usher protein FimD VFG0446 Protein 3e-159 43