Gene Information

Name : UM146_07275 (UM146_07275)
Accession : YP_006110358.1
Strain : Escherichia coli UM146
Genome accession: NC_017632
Putative virulence/resistance : Virulence
Product : Thiazolinyl-S-HMWP1 reductase YbtU
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1547498 - 1548598 bp
Length : 1101 bp
Strand : -
Note : COG4693 Oxidoreductase (NAD-binding), involved in siderophore biosynthesis

DNA sequence :
ATGATGCCGTCCGCCTCCCCAAAGCAACGCGTACTGATTGTGGGCGCCAAATTTGGCGAAATGTACCTGAATGCCTTTAT
GCAGCCCCCGGAGGGGCTGGAACTGGTCGGCCTGCTGGCGCAGGGAAGCGCCCGTTCAAGAGAGCTGGCTCATGCGTTTG
GCATTCCGCTGTATACCTCGCCGGAACAGATAACCAGGATGCCGGATATCGCCTGTATTGTCGTGCGTTCGACCGTCGCC
GGAGGAACCGGTACGCAGCTTGCCAGACACTTTCTGACGCGCGGCGTACACGTCATTCAGGAGCATCCCCTCCACCCGGA
TGACATCAGTTCCTTACAAACGCTGGCGCAGGAACAGGGCTGCTGCTATTGGGTAAACACGTTTTATCCGCATACGCGCG
CGGGACGCACATGGCTTCGCGATGCGCAGCAGCTGCGTCGCTGCCTGGCTAAGACGCCGCCGGTAGTCCACGCCACCACC
AGCCGACAGTTGCTCTACTCCACTCTGGATTTGTTGTTGCTGGCTCTGGGCGTTGATGCCGCCGCCGTGGAGTGCGACGT
GGTTGGCAGCTTTAGCGATTTTCACTGTCTGAGACTCTTCTGGCCGGAGGGAGAAGCCTGCCTGCTGCTTCAGCGCTATC
TCGATCCTGACGATCCAGATATGCATAGCCTTATCATGCACCGCCTGCTGCTGGGCTGGCCGGAAGGTCATCTTTCGCTG
GAGGCGAGCTACGGCCCCGTCATCTGGTCATCCAGCCTGTTTGTCGCAGACCATCAGGAGAACGCCCACAGCCTCTACCG
CAGACCGGAGATCCTGCGCGATCTGCCGGGTCTGATGCGCAGCGCGGCGCCCCTGAGCTGGCGCGACTGCTGCGAAACCG
TCGGGCCGGAGGGCGTCAGCTGGTTGCTACACCAGTTGCGCAGCAATCTGGCGGGCGAACATCCACCAGCGGCCTGCCAA
AGCGTACATCAGATCGCGTTATCACGTTTATGGCAGCAGATTTTACGTAAGACCGGCAATGCGGAGATCAGACGCCTGAC
GCCGCCGCACCACGACCGGTTAGCCGGTTTCTACAACGATGATGATAAGGAGGCGCTGTGA

Protein sequence :
MMPSASPKQRVLIVGAKFGEMYLNAFMQPPEGLELVGLLAQGSARSRELAHAFGIPLYTSPEQITRMPDIACIVVRSTVA
GGTGTQLARHFLTRGVHVIQEHPLHPDDISSLQTLAQEQGCCYWVNTFYPHTRAGRTWLRDAQQLRRCLAKTPPVVHATT
SRQLLYSTLDLLLLALGVDAAAVECDVVGSFSDFHCLRLFWPEGEACLLLQRYLDPDDPDMHSLIMHRLLLGWPEGHLSL
EASYGPVIWSSSLFVADHQENAHSLYRRPEILRDLPGLMRSAAPLSWRDCCETVGPEGVSWLLHQLRSNLAGEHPPAACQ
SVHQIALSRLWQQILRKTGNAEIRRLTPPHHDRLAGFYNDDDKEAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ybtU YP_853077.1 yersiniabactin biosynthetic protein Virulence PAI IV APEC-O1 Protein 2e-162 100
ybtU CAA21392.1 - Virulence HPI Protein 5e-161 99
irp3 YP_002346900.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 2e-161 99
ybtU NP_669708.2 thiazolinyl-S-HMWP1 reductase Virulence HPI Protein 2e-161 99
ybtU NP_993005.2 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 2e-161 99
ybtU YP_070122.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 2e-161 99
irp3 YP_001006817.1 yersiniabactin biosynthetic protein YbtU Virulence HPI Protein 5e-162 98
irp3 CAA73128.1 Irp3 protein Virulence HPI Protein 2e-161 98
nrpU YP_002152319.1 siderophore biosynthetic protein Virulence Not named Protein 2e-63 43