Gene Information

Name : UM146_05125 (UM146_05125)
Accession : YP_006109942.1
Strain : Escherichia coli UM146
Genome accession: NC_017632
Putative virulence/resistance : Virulence
Product : outer membrane usher protein YfcU
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1054738 - 1057386 bp
Length : 2649 bp
Strand : +
Note : COG3188 P pilus assembly protein, porin PapC

DNA sequence :
ATGCCTAATCACTCAAATTTTCGGCTGCGGGGAATCGCCTGCTATATTGCGCTGGCAATCTCTGGTGGATCAGTCAATGC
ATGGGCTGATGATTCAATTCAATTTGACCCCCGTTTCCTTGAGTTAAAGGGCGATACGAAAATTGATCTCGGTAAGTTTT
CAAAAAAAGGGTATGTCGACGCGGGTAAATATAATTTACGTGTATTTATAAATAAACAACCCCTTTCTGATGAATACGAC
ATTAACTGGTACGTCTCTGAAAACGATCCAACAAAAAACTATGCCTGCCTGACACCTGAGTTAGTGGCGGCGCTGGGGCT
GAAAGAAGGGATAGCAAAAAGCCTGCAGTGGACGCACAACGATGAATGCCTTAAACCAGGTCAATTAGACGGGATGGAAG
TCGAGAATGATTTAAGCCAGTCGGCGTTGCTGCTGACAGTGCCACAGGCTTACCTCGAATATACCAGCAGCGACTGGGAC
CCTCCCTCACGTTGGGACGACGGTATTCCTGGCCTGATTGCCGACTACAGCCTCAATGCGCAAACTCGCCACCAGGAGCA
GGGGGGCGAGGACTCACATGATATCAGCGGCAACGGTACCGTTGGGGCGAACCTGGGGGCATGGCGTTTCCGTGCAGACT
GGCAAAGTGATTATCAGCACACCCGCAGCAACGATGACGACGATGACAGCAGTAACAGTACAACGAGCAAAAACTGGGAC
TGGAGCCGTTATTACGCCTGGCGGGCCTTACCCTCTTTAAAAGCGAAGCTGTCGCTGGGGGAAGATTATCTCAATTCCGA
TATTTTCGACGGCTTTAACTATATCGGCAGCAGCGTCAGCACCGATGACCAGATGCTGCCGCCCAACCTGCGCGGCTATG
CGCCGGATGTCTCCGGCGTGGCGCACAGCAGTGCAAAAGTCACCATTAGCCAGATGGGCCGGGTACTTTACGAAACCCAG
GTTCCCGCCGGGCCATTCCGCATTCAGGATATCGGCGACTCCGTCTCCGGCACACTGCACGTCCGCGTTGAAGAACAGAA
TGGTCAGGTGCAGGAATATGACGTTACCACCGCATCTATGCCATTCCTCACGCGCCAGGGGCAGGTGCGTTACAAAGTGA
TGATGGGGCGTCCGGAAGACTGGAACCACAAGACCGAAGGCGGCTTTTTCTCCGGCGGAGAAGCGTCATGGGGGGTGGCA
GATGGCTGGTCGCTCTACGGTGGTGCGCTGGCAGATAAACACTATCAGTCGGCGGCGATGGGGGTGGGGCGCGACCTCGC
ACAGTTTGGCGCGCTGGCGTTCGATGTGACTCACTCGCACGTCAACCTGGATCATGACAGCGCATACGGCAAAGGAAAAC
TGGACGGCAACTCCTTTCGCGTGAGCTATGCCAAAGACTTTGACGAACTCAACAGCCGCGTCACCTTTGCAGGCTACCGT
TTTTCTGAAAAGAACTTCATGACCATGAGCGAGTATCTGGACGCGAACCAGTCGGACATGGCGCGGACCGGTAACGACAA
AGAGATGTATACGATCACCTATAACCAGAACTTTGCCGCTGCGGGTGTTTCGATCTATCTCAACTACTCCCATCGTACTT
ACTGGGATCGCCCGGAACAGACAAACTATAACCTGATGTTTTCCCACTATTTTAATATGGGGAGCATTCGCAACATGAGC
ATCTCGGTGACCGGCTATCGCTACGAATATGACGATAATGCGGATAAGGGGATGTACCTCAGTATGAGCATTCCGTGGAG
CGACAGCAGCACCGTGACCTACAACGGTTCCTACGGCAGCGGATCGGACAGCAGCCAGGTCGGTTACTTTAAGCGCGTCG
ATGACGCAACGCACTACCAGGTTAACGTTGGCACCAGCGAGCAGCACGGCAGCGTGGATGGTTATCTGAGCCACGACGGT
TCGCTGGCGAAGGTTGATCTCAGCGCCAACTACCATGAAGGGGAATACCGTTCGGCGGGGATCGCCTTACAGGGCGGGGC
AACGCTGACCGCGCATGGTGGGGCCCTGCACCGTACCCAGAACATGGGCGGCACGCGCCTGCTGATTGACGCCGACGGGA
TTGCCAACGTGCCGGTCGAAAGCAACGGCGCGCCGGTGTACACCAATATGTTTGGCAAGGCGGTGGTCGCCGATATTAAC
AACTACTATCGCAATCAGGCGTATATCGATTTAAACAACTTGCCGGAAGATGCGGAAGCCACCCAGTCGGTGGTGCAGGC
AACCCTGACGGAAGGCGCAATCGGCTATCGCAAATTCAAAGTGATCAGCGGGCAAAAAGCGATGGCGGTACTGAGGTTGC
GTGACGGTAGCTACCCGCCGTTTGGCGCGGAAGTGAAAAATGACGAGCAGCAGCAGGTTGGCATTGTGGATGATGAAGGC
AATGTCTATCTGGCGGGGGTCAATGCGGGCGAGCATATGATGGTGTTCTGGGAAGGCAGCGCACAATGCGAGATCGTATT
GCCGAAGCCGCTACCTGCCGATTTGTTCAGCGGCCTGTTGTTGCCGTGTGAACAAAAGGGAACGGCAGCCCCTGATTCTT
CAGCGCCAGAAATTAAGCCTGTTATTCAGGACCAGACGCGGCAAGTCACACCAACGGAAGCGCCGACGTCAATTTCAGCA
ACTCAATAA

Protein sequence :
MPNHSNFRLRGIACYIALAISGGSVNAWADDSIQFDPRFLELKGDTKIDLGKFSKKGYVDAGKYNLRVFINKQPLSDEYD
INWYVSENDPTKNYACLTPELVAALGLKEGIAKSLQWTHNDECLKPGQLDGMEVENDLSQSALLLTVPQAYLEYTSSDWD
PPSRWDDGIPGLIADYSLNAQTRHQEQGGEDSHDISGNGTVGANLGAWRFRADWQSDYQHTRSNDDDDDSSNSTTSKNWD
WSRYYAWRALPSLKAKLSLGEDYLNSDIFDGFNYIGSSVSTDDQMLPPNLRGYAPDVSGVAHSSAKVTISQMGRVLYETQ
VPAGPFRIQDIGDSVSGTLHVRVEEQNGQVQEYDVTTASMPFLTRQGQVRYKVMMGRPEDWNHKTEGGFFSGGEASWGVA
DGWSLYGGALADKHYQSAAMGVGRDLAQFGALAFDVTHSHVNLDHDSAYGKGKLDGNSFRVSYAKDFDELNSRVTFAGYR
FSEKNFMTMSEYLDANQSDMARTGNDKEMYTITYNQNFAAAGVSIYLNYSHRTYWDRPEQTNYNLMFSHYFNMGSIRNMS
ISVTGYRYEYDDNADKGMYLSMSIPWSDSSTVTYNGSYGSGSDSSQVGYFKRVDDATHYQVNVGTSEQHGSVDGYLSHDG
SLAKVDLSANYHEGEYRSAGIALQGGATLTAHGGALHRTQNMGGTRLLIDADGIANVPVESNGAPVYTNMFGKAVVADIN
NYYRNQAYIDLNNLPEDAEATQSVVQATLTEGAIGYRKFKVISGQKAMAVLRLRDGSYPPFGAEVKNDEQQQVGIVDDEG
NVYLAGVNAGEHMMVFWEGSAQCEIVLPKPLPADLFSGLLLPCEQKGTAAPDSSAPEIKPVIQDQTRQVTPTEAPTSISA
TQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pixC CAE85159.1 PixC protein Not tested PAI V 536 Protein 1e-144 43
prfC CAD42029.1 PrfC protein Virulence PAI II 536 Protein 4e-138 42
papC YP_854254.1 outer membrane usher protein PapC Virulence PAI I APEC-O1 Protein 5e-137 42
papC AAZ04424.1 outer membrane usher protein Virulence PAI I APEC-O1 Protein 4e-137 42
papC NP_755465.1 PapC protein Virulence PAI I CFT073 Protein 5e-138 42
papC YP_002414015.1 Outer membrane usher protein PapC Not tested Not named Protein 4e-138 42
papC_2 NP_757034.1 PapC protein Virulence PAI II CFT073 Protein 3e-138 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
UM146_05125 YP_006109942.1 outer membrane usher protein YfcU VFG1548 Protein 2e-138 42
UM146_05125 YP_006109942.1 outer membrane usher protein YfcU VFG0884 Protein 2e-138 42
UM146_05125 YP_006109942.1 outer membrane usher protein YfcU VFG0895 Protein 1e-138 42