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Name : hbp (ECOK1_0270) Accession : YP_006099515.1 Strain : Escherichia coli IHE3034 Genome accession: NC_017628 Putative virulence/resistance : Virulence Product : hemoglobin-binding protease Hbp Function : - COG functional category : - COG ID : - EC number : 3.4.21.- Position : 296634 - 300764 bp Length : 4131 bp Strand : - Note : identified by similarity to SP:O88093; match to protein family HMM PF02395; match to protein family HMM PF03797; match to protein family HMM TIGR01414 DNA sequence : ATGAATAAAATATACGCTCTAAAATATTGTTATATTACTAACACAGTAAAGGTTGTCTCTGAACTAGCCCGAAGGGTATG TAAAGGGAGTACCCGCAGAGGAAAAAGACTTTCAGTACTTACCTCTCTGGCACTATCTGCATTACTCCCAACCGTTGCTG GTGCATCAACGGTTGGTGGCAACAATCCTTACCAGACATACCGCGACTTTGCAGAAAACAAAGGGCAGTTTCAGGCTGGC GCAACAAACATTCCTATTTTTAATAATAAAGGGGAATTAGTAGGACATCTTGATAAAGCGCCCATGGTTGATTTTAGCAG TGTGAATGTAAGCTCAAATCCCGGCGTTGCAACATTAATTAACCCGCAATATATAGCCAGTGTAAAACATAATAAAGGAT ATCAGAGCGTCAGCTTCGGTGATGGTCAGAACAGTTACCATATTGTGGATCGTAATGAACACAGTTCATCTGATCTCCAC ACACCAAGACTTGATAAGCTCGTAACTGAGGTTGCTCCGGCTACCGTAACCAGCTCATCAACAGCTGATATATTGAACCC TTCAAAATACTCGGCATTCTACAGGGCTGGTTCGGGAAGTCAGTATATTCAGGATAGTCAGGGTAAGCGACATTGGGTAA CAGGTGGGTATGGTTATCTGACAGGAGGAATACTCCCGACATCATTCTTTTATCACGGCTCAGACGGCATTCAGCTGTAT ATGGGGGGCAACATACATGATCATAGCATCCTGCCCTCTTTTGGAGAGGCCGGCGACAGTGGTTCTCCATTATTTGGCTG GAATACGGCCAAAGGGCAGTGGGAACTGGTCGGTGTTTACTCGGGAGTAGGAGGGGGGACCAATTTGATATATTCTCTTA TTCCTCAGAGTTTTCTCTCACAGATCTATTCAGAGGATAATGACGCTCCCGTCTTTTTTAATGCCTCATCCGGCGCCCCC CTGCAATGGAAATTTGACAGCAGCACCGGCACTGGCTCTCTGAAACAGGGTTCCGATGAATATGCCATGCACGGGCAAAA AGGTTCTGACCTGAACGCAGGTAAAAATCTGACATTCCTGGGACATAATGGTCAGATTGACCTGGAAAACTCTGTCACGC AGGGTGCCGGTTCACTGACATTTACTGATGACTACACTGTCACCACTTCAAACGGAAGTACCTGGACCGGGGCCGGTATT ATTGTGGACAAGGATGCCTCCGTAAACTGGCAGGTTAATGGTGTGAAAGGTGACAACCTGCATAAAATCGGCGAAGGAAC CCTGGTTGTACAGGGAACCGGTGTTAATGAGGGCGGCCTGAAAGTCGGGGATGGGACCGTTGTCCTCAATCAGCAGGCTG ACAGTTCAGGACACGTTCAGGCATTCAGTAGCGTGAATATTGCCAGCGGCCGCCCGACAGTCGTGCTGGCAGACAACCAG CAGGTTAATCCGGACAATATATCCTGGGGCTACCGGGGGGGGGTTCTGGATGTTAACGGGAATGACCTGACATTTCATAA GCTGAATGCCGCCGATTATGGCGCAACTCTCGGTAACAGCAGTGATAAAACGGCTAATATCACTCTGGATTATCAGACGC GTCCGGCAGACGTAAAAGTTAATGAATGGTCATCATCAAACAGGGGAACAGTAGGTTCATTATATATTTATAATAATCCC TATACTCATACCGTCGATTATTTTATCCTGAAAACAAGTAGTTATGGCTGGTTCCCTACCGGTCAGGTCAGTAACGAGCA CTGGGAATATGTCGGACATGACCAGAACAGTGCACAGGCGCTGCTTGCAAACAGAATTAATAATAAAGGGTATCTGTATC ATGGCAAGTTGCTGGGAAATATTAATTTCTCAAATAAAGCAACCCCGGGTACAACCGGCGCATTGGTTATGGACGGCTCA GCGAATATGTCCGGTACATTTACTCAGGAAAACGGTCGTCTGACCATTCAGGGCCACCCGGTTATCCATGCTTCAACGTC TCAGAGTATTGCAAATACAGTCTCGTCTCTGGGCGACAATTCCGTTCTGACACAGCCCACCTCATTTACACAGGATGACT GGGAGAACAGGACGTTCAGCTTTGGTTCGCTCGTGTTAAAAGATACAGACTTTGGTCTGGGCCGCAATGCCACACTGAAC ACAACCATCCAGGCAGATAACTCCAGCGTCACGCTGGGCGACAGTCGGGTATTTATCGACAAAAAAGATGGCCAGGGAAC AGCATTTACCCTTGAAGAAGGCACATCTGTTGCAACTAAAGATGCAGATAAAAGCGTCTTCAACGGCACCGTCAACCTGG ATAATCAGTCAGTGCTGAATATCAATGAGATATTCAATGGCGGAATACAGGCGAACAACAGTACCGTGAATATCTCCTCA GACAGTGCCGTTCTGGAGAACTCAACGCTGACCAGTACCGCCCTGAATCTGAACAAGGGAGCAAATGTTCTGGCCAGTCA GAGTTTTGTTTCTGACGGTCCGGTGAATATTTCTGATGCCACCCTGAGTCTGAACAGCCGTCCTGATGAGGTATCTCACA CACTTTTACCTGTATACGATTATGCCGGTTCATGGAACCTGAAGGGAGACGATGCCCGCCTGAACGTGGGGCCGTACAGT ATGTTGTCAGGTAATATCAATGTTCAGGATAAAGGGACTGTCACCCTCGGAGGGGAAGGGGAACTGAGTCCTGACCTGAC TCTTCAGAATCAGATGTTGTACAGCCTGTTTAACGGGTACCGCAATACCTGGAGCGGGAGCCTGAATGCACCGGATGCCA CCGTCAGCATGACAGACACCCAGTGGTCGATGAACGGAAACTCCACGGCAGGAAATATGAAACTTAACCGGACAATAGTC GGTTTTAACGGGGGAACATCATCGTTCACGACACTGACAACAGATAATCTGGACGCGGTTCAGTCAGCATTTGTCATGCG TACAGACCTTAACAAGGCAGACAAACTGGTGATAAACAAGTCGGCAACAGGTCATGACAACAGCATCTGGGTTAACTTCC TGAAAAAACCCTCTGACAAGGACACGCTTGATATTCCACTGGTCAGCGCACCTGAAGCGACAGCTGATAATCTGTTCAGG GCATCAACACGGGTTGTGGGATTCAGTGATGTCACCCCCACCCTTAGTGTCAGAAAAGAGGACGGGAAAAAAGAGTGGGT CCTCGATGGTTACCAGGTTGCACGTAACGACGGCCAGGGTAAGGCTGCCGCCACATTCATGCACATCAGCTATAACAACT TCATCACTGAAGTTAACAACCTGAACAAACGCATGGGCGATTTGAGGGATATTAACGGCGAAGCCGGTACGTGGGTGCGT CTGCTGAACGGTTCCGGCTCTGCTGATGGCGGTTTCACTGACCACTATACCCTGCTGCAGATGGGGGCTGACCGTAAGCA CGAACTGGGAAGTATGGACCTGTTTACCGGCGTGATGGCCACCTACACTGACACAGATGCGTCAGCAGGCCTGTACAGCG GTAAAACAAAATCATGGGGTGGTGGTTTCTATGCCAGTGGTCTGTTCCGGTCCGGCGCTTACTTTGATTTGATTGCCAAA TATATTCACAATGAAAACAAATATGACCTGAACTTTGCCGGAGCTGGTAAACAGAACTTCCGCAGCCATTCACTGTATGC AGGTGCAGAAGTCGGATACCGTTATCATCTGACAGATACGACGTTTGTTGAACCTCAGGCGGAACTGGTCTGGGGAAGAC TGCAGGGCCAAACATTTAACTGGAACGACAGTGGAATGGATGTCTCAATGCGTCGTAACAGCGTTAATCCTCTGGTAGGC AGAACCGGCGTTGTTTCCGGTAAAACCTTCAGTGGTAAGGACTGGAGTCTGACAGGCCGTGCCGGCCTGCATTATGAGTT CGATCTGACGGACAGTGCTGACGTTCACCTGAAGGATGCAGCGGGAGAACATCAGATTAATGGCAGAAAAGACGGTCGTA TGCTTTACGGTGTGGGGTTAAATGCCCGGTTTGGCGACAATACGCGTCTGGGGCTGGAAGTTGAACGCTCTGCATTCGGT AAATACAACACAGATGATGCGATAAACGCTAATATTCGTTATTCATTCTGA Protein sequence : MNKIYALKYCYITNTVKVVSELARRVCKGSTRRGKRLSVLTSLALSALLPTVAGASTVGGNNPYQTYRDFAENKGQFQAG ATNIPIFNNKGELVGHLDKAPMVDFSSVNVSSNPGVATLINPQYIASVKHNKGYQSVSFGDGQNSYHIVDRNEHSSSDLH TPRLDKLVTEVAPATVTSSSTADILNPSKYSAFYRAGSGSQYIQDSQGKRHWVTGGYGYLTGGILPTSFFYHGSDGIQLY MGGNIHDHSILPSFGEAGDSGSPLFGWNTAKGQWELVGVYSGVGGGTNLIYSLIPQSFLSQIYSEDNDAPVFFNASSGAP LQWKFDSSTGTGSLKQGSDEYAMHGQKGSDLNAGKNLTFLGHNGQIDLENSVTQGAGSLTFTDDYTVTTSNGSTWTGAGI IVDKDASVNWQVNGVKGDNLHKIGEGTLVVQGTGVNEGGLKVGDGTVVLNQQADSSGHVQAFSSVNIASGRPTVVLADNQ QVNPDNISWGYRGGVLDVNGNDLTFHKLNAADYGATLGNSSDKTANITLDYQTRPADVKVNEWSSSNRGTVGSLYIYNNP YTHTVDYFILKTSSYGWFPTGQVSNEHWEYVGHDQNSAQALLANRINNKGYLYHGKLLGNINFSNKATPGTTGALVMDGS ANMSGTFTQENGRLTIQGHPVIHASTSQSIANTVSSLGDNSVLTQPTSFTQDDWENRTFSFGSLVLKDTDFGLGRNATLN TTIQADNSSVTLGDSRVFIDKKDGQGTAFTLEEGTSVATKDADKSVFNGTVNLDNQSVLNINEIFNGGIQANNSTVNISS DSAVLENSTLTSTALNLNKGANVLASQSFVSDGPVNISDATLSLNSRPDEVSHTLLPVYDYAGSWNLKGDDARLNVGPYS MLSGNINVQDKGTVTLGGEGELSPDLTLQNQMLYSLFNGYRNTWSGSLNAPDATVSMTDTQWSMNGNSTAGNMKLNRTIV GFNGGTSSFTTLTTDNLDAVQSAFVMRTDLNKADKLVINKSATGHDNSIWVNFLKKPSDKDTLDIPLVSAPEATADNLFR ASTRVVGFSDVTPTLSVRKEDGKKEWVLDGYQVARNDGQGKAAATFMHISYNNFITEVNNLNKRMGDLRDINGEAGTWVR LLNGSGSADGGFTDHYTLLQMGADRKHELGSMDLFTGVMATYTDTDASAGLYSGKTKSWGGGFYASGLFRSGAYFDLIAK YIHNENKYDLNFAGAGKQNFRSHSLYAGAEVGYRYHLTDTTFVEPQAELVWGRLQGQTFNWNDSGMDVSMRRNSVNPLVG RTGVVSGKTFSGKDWSLTGRAGLHYEFDLTDSADVHLKDAAGEHQINGRKDGRMLYGVGLNARFGDNTRLGLEVERSAFG KYNTDDAINANIRYSF |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD66214.1 | putative hemoglobin protease | Not tested | PAI III 536 | Protein | 0.0 | 99 |
| vat | YP_851472.1 | vacuolating autotransporter | Not tested | PAI III APEC-O1 | Protein | 0.0 | 99 |
| vat | AAO21903.1 | vacuolating autotransporter toxin | Virulence | Not named | Protein | 0.0 | 98 |
| pic | NP_838464.1 | serine protease precurser | Virulence | SHI-1 | Protein | 0.0 | 49 |
| she | AAB58244.1 | mucinase | Virulence | SHI-1 | Protein | 0.0 | 48 |
| pic | NP_708747.3 | serine protease | Not tested | SHI-1 | Protein | 0.0 | 48 |
| pic | AAK00464.1 | Pic | Virulence | SHI-1 | Protein | 0.0 | 48 |
| unnamed | CAC39286.1 | hypothetical protein | Not tested | LPA | Protein | 0.0 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| hbp | YP_006099515.1 | hemoglobin-binding protease Hbp | VFG0904 | Protein | 0.0 | 99 |
| hbp | YP_006099515.1 | hemoglobin-binding protease Hbp | VFG1689 | Protein | 0.0 | 99 |
| hbp | YP_006099515.1 | hemoglobin-binding protease Hbp | VFG0635 | Protein | 0.0 | 48 |
| hbp | YP_006099515.1 | hemoglobin-binding protease Hbp | VFG0861 | Protein | 0.0 | 48 |
| hbp | YP_006099515.1 | hemoglobin-binding protease Hbp | VFG0903 | Protein | 0.0 | 48 |
