Gene Information

Name : aafC (EC042_pAA031)
Accession : YP_006099162.1
Strain :
Genome accession: NC_017627
Putative virulence/resistance : Virulence
Product : aggregative adherence fimbria II usher protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 23011 - 25533 bp
Length : 2523 bp
Strand : -
Note : -

DNA sequence :
ATGACATGTACATTACTTCATGTTGAAGATGTTATAGCTCGCACATATTCTTTTAATTCATCGCTGCTTAGTGGTGGAGG
AAAAGGTGTTGATTTGACCTTATTTGAAGAGGGAGGGCAACTGCCGGGCATTTATCAAACTGACATAATCCTGAATGGTT
CTCGTGTTGATTCACTGGAGATGCCCTTTCATACAGAAAAGGATGAGAATGGCAGGCCTTATCTGAAGACTTGTCTGACC
CAAGAGATGCTGGCGCGTTACGGGGTGAAGACAGAGGAATATCCGGCCCTATTCCGTTCTTTGGGTGGTGGGAGTGATAC
GTCTGGTGAAAGGGGAGTATGTGCTGACCTGTCGGCGATACCGCAAGCCACGGAGAACTATCAGTTTGCTGCACAGCAAC
TGGTGCTGGGTATTCCACAGGTGGCACTTCGCCCCCTGCTGAGGGGGATTGCGCCAGAGGTTCTATGGGACGACGGTATA
CCAGCATTTCTGCTGAATTGGCAAGCGAACGCGGGCCGTTCGGAATACCGGGGATACATAAAGGATGTCGAGGATTATTT
CTGGAGCAGTTTGGAACCGGGTATCAACATTGGTTCTTGGCGCATCAGAAACCTGACGACCTGGAACAAATCGTCCGGGC
AATCGGGGAAATGGGAGAGTTTATACATTCGTGCCGAACGAGGGCTAAACAGTCTAAAAAGCCGTCTGACGCTGGGTGAG
AACTACACGCCGTCAGACATCTTTGACAGCGTTCCTTTTCGAGGGGGGATGTTGAGTTCTGATGAGAGCATGGTGCCCTA
TAACCAGCGTGAATTTGCACCTGTGGTGAGAGGAATTGCCCGCACCCAGGCCCGAATCGAAGTGCGACAGAACGGGTATC
TGATACAGAGTCAGACGGTGGCTCCGGGGGCATTTGCCCTGACGGACTTGCCGGTAACGGGTTCCGGCAGTGACCTGCAG
GTGACAGTGCGGGAATCAGACGGGACAGTCCAGGTTTTCACTGTACCATTCACCACACCTGCTATTGCACTGCGTGAGGG
GTATCTGAAGTATAACGTCATGGCAGGGCAGTATCGTTCATCAGATGATGCTGTTGAAGATAGTACTCTGGGACAGGTGA
TGGGCATGTATGGGTTGCCATGGGGGCTGACGGTATTTGGCGGGCTTCAGGGTGCTGAGCATTATCAGTCTGCAGCACTG
GGGCTGGGCTGGTCACTGGGAAAACTCGGGGCGGTATCACTGGACACGATTCATTCCCGTGGTCAGCAGAAGGGATATAA
TTATGAGACAGGGAACACTTGGCGTATCCGTTATAACAAGTCCTTTGAGCTTACGGGTACGAGTTTTACGGCAGCAAGTT
ACCAGTATTCATCATCAGGCTACCACACACTGTCGGATGTGTTGGAAACATACCGTGATGACGGCAGGTTCGCATACAGA
AGTACTGACAGCCGAACTAGTCGTACCACGGTAAATCTGAGCCAGTCACTTGGACGGTGGGGATATCTGGGGCTGAACGG
CAGTCGGGATGAGTATCGTGATAGGCCACACCAAGATTATATTGGTGCGTCATATGGTGCATCGTGGAACCGCATGTCCC
TGTCAGTCAACTGGTCGCGCAACCATAGCACTAGGGGATATTACGGTAGCAAGTCACGTACGGAAGATAGTATCAGTATA
TGGATGAGTATTCCGCTGGAGAGCTGGCTGGGCAGGTCGGATAACAACATCAGTGCTACGGCACAGATGCAGCGTTCCAC
GGAACAGAATACACGTTATGAATTGGGCCTGAACGGACGTGCTTTTGACCGCAGGCTGTTCTGGGAAGTTCATGAGCAGA
TGGTGTCGGGCAGTGAATATAATACAGGCACCAGTCGTCTGAACCTGCGCTGGTCGGGGACTTATGGTGAGCTGGCAGGG
ATGTATAGTTACAGCAGTAACATGCGGCAGATTAACGCCGGAATGTCAGGAAGCATGGTTGCTCACGGTGAGGGGGTCAC
ATTTGGTCAGAGAGCCGGAGACACAGTGACTCTGATTGCCGCACCTGGCGTGAGCGGGGCCTCTGTGGGAGACTGGCCAG
GTGTCAGAACCGATTTCCGCGGATATGCCCTAGCCGGTTATGCATCACCGTACCAGGAGAACGTTATCACACTGGACCCG
ACGACGTTCCCGGAAGATGCGGAAGTGCCACAGACGGACAGCCGAGTTGTGCCGACGAAGGGGGCAGTGGTCCGGGCCGG
GTTCAGGACCCGCGTGGGTGGTCGTGCACTGGTGAGCCTGACCCGTCAGGACGGATCCTCCCTGCCATTTGGTGCGATAG
TGACCTTGGAAGGAAAGCCGGGGGAGACATCCGGCTCTGCCGGTGTGGTAGATGACAAGGGGAGGGTGTATCTGAGCGGA
CTGTCTGAAACTGGAAAACTGAAGGCTCAGTGGGGAGAGAACAGTCTATGTCATGCGGACTACCGTCTTCCGGAAGAGAA
AGGGCCTGCGGGTATTTTCCTGACCCGCACGGTATGTATGTGA

Protein sequence :
MTCTLLHVEDVIARTYSFNSSLLSGGGKGVDLTLFEEGGQLPGIYQTDIILNGSRVDSLEMPFHTEKDENGRPYLKTCLT
QEMLARYGVKTEEYPALFRSLGGGSDTSGERGVCADLSAIPQATENYQFAAQQLVLGIPQVALRPLLRGIAPEVLWDDGI
PAFLLNWQANAGRSEYRGYIKDVEDYFWSSLEPGINIGSWRIRNLTTWNKSSGQSGKWESLYIRAERGLNSLKSRLTLGE
NYTPSDIFDSVPFRGGMLSSDESMVPYNQREFAPVVRGIARTQARIEVRQNGYLIQSQTVAPGAFALTDLPVTGSGSDLQ
VTVRESDGTVQVFTVPFTTPAIALREGYLKYNVMAGQYRSSDDAVEDSTLGQVMGMYGLPWGLTVFGGLQGAEHYQSAAL
GLGWSLGKLGAVSLDTIHSRGQQKGYNYETGNTWRIRYNKSFELTGTSFTAASYQYSSSGYHTLSDVLETYRDDGRFAYR
STDSRTSRTTVNLSQSLGRWGYLGLNGSRDEYRDRPHQDYIGASYGASWNRMSLSVNWSRNHSTRGYYGSKSRTEDSISI
WMSIPLESWLGRSDNNISATAQMQRSTEQNTRYELGLNGRAFDRRLFWEVHEQMVSGSEYNTGTSRLNLRWSGTYGELAG
MYSYSSNMRQINAGMSGSMVAHGEGVTFGQRAGDTVTLIAAPGVSGASVGDWPGVRTDFRGYALAGYASPYQENVITLDP
TTFPEDAEVPQTDSRVVPTKGAVVRAGFRTRVGGRALVSLTRQDGSSLPFGAIVTLEGKPGETSGSAGVVDDKGRVYLSG
LSETGKLKAQWGENSLCHADYRLPEEKGPAGIFLTRTVCM

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
afaC AAD44022.2 AfaC Virulence PAI-I AL862 Protein 0.0 72
afaC ADD91743.1 putative AfaC-VIII usher protein Not tested PAI-I AL862 Protein 0.0 72
safC NP_454907.1 outer-membrane fimbrial usher protein Not tested SPI-6 Protein 0.0 50

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
aafC YP_006099162.1 aggregative adherence fimbria II usher protein VFG0853 Protein 0.0 99
aafC YP_006099162.1 aggregative adherence fimbria II usher protein VFG0944 Protein 0.0 82
aafC YP_006099162.1 aggregative adherence fimbria II usher protein VFG0849 Protein 0.0 68
aafC YP_006099162.1 aggregative adherence fimbria II usher protein VFG0857 Protein 0.0 68
aafC YP_006099162.1 aggregative adherence fimbria II usher protein VFG0419 Protein 1e-158 44