Gene Information

Name : EC042_4741 (EC042_4741)
Accession : YP_006098991.1
Strain : Escherichia coli 042
Genome accession: NC_017626
Putative virulence/resistance : Unknown
Product : integrase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 5081722 - 5082975 bp
Length : 1254 bp
Strand : +
Note : -

DNA sequence : 
ATGGCTCTGACAGATATCAAAGTGCGTTCTGCAAAACCACAGGAAAAGGAGTATACCCTTGCCGATGGAGATGGCATGTT
TTTGCTCATTCACCCTAACGGCTCAAAATACTGGCGGTTTCGCTTTCGCTTTGGTGGTAAGCAGCACCTGATGGCATTTG
GGGTTTATCCTGAAACGTCACTGGCTGATGCTCGTCAAAAAAGGGAAGAGGCCAGAAAACTTGTTGCTGCAGGCATCGAT
CCCCGTGAACACAAACGTGCAGTGAAAGAAGAGCAGACGAAAGAGGCTATTACCTTTGAGTCAGTTGCCAGAGAGTGGCA
CGCAGTAAATAAAAAATGGACAGAAGAACATAGCCGACGGGTGCTGAAGAGCCTGGAAGATAATTTGTTCCCAGCAATTG
GGAAGCGGAGTATTGATAGTTTTAGTACGCGCGATCTCCTTGTCCCTATCAAAGTAGTTGAGGCTACAGGGCGTCTTGAA
GTGGCTTCGCGTCTTCAGCAGCGTACCAATGCGATTATGCGTTGTGCAGTGCAAAGCGGTTTGATCGATTACAATCCTGC
TCAGGAGATGGCTGGGGCAGTTGCTTCAAGTAATCGTGTCCATCGACCAGCACTTGAACTGAAACGCTTACCTGAACTAC
TCCAGCGAATTGATAGCTACTCCGGACGACCTTTAACCCGTCTGGCTGTTGAGCTCACGTTATTAATCTTTATTCGTTCC
AGTGAGTTGCGCTTTGCCCGTTGGCCAGAGATCGATTTTGAAAGGGCAATGTGGACAATCCCGGCAGAACGAGAAGCTAT
TGAAGGAGTGAAGCATTCGGAACGTGGCTCGAAAATGCGTACTCCTCATTTAGTGCCGCTTTCTCGTCAGGCACTGGCAA
TCCTTAAACAGGTTCATAAGCTTAGTGGCGAGCGCGATTTTGTTTTCGTTGGAGATCACAATCCTTGTAAACCGATGAGT
GAAAATACAGTGAACAAGGCGCTGCGCGTGATGGGATATGACACTAAGATTGAGGTTTGCGGTCATGGCTTCAGGACCAT
GGCATGTAGCTCGTTGATTGAATCAGGGCTGTGGTCTAGGAACGCTGTTGAAAGGCAGATGAGCCATATGGAGCGTAACT
CTGTACGTGCTGCTTACATTCATAAGGCTCAACACTTGGATGAGCGTAAAATGATGCTGCAGTGGTGGGCAGATTTTCTT
GATGTAAATCGGGTGAAGGGCGTCAGCCCATTTGATTTTGCCAAGGAGAAATGA

Protein sequence : 
MALTDIKVRSAKPQEKEYTLADGDGMFLLIHPNGSKYWRFRFRFGGKQHLMAFGVYPETSLADARQKREEARKLVAAGID
PREHKRAVKEEQTKEAITFESVAREWHAVNKKWTEEHSRRVLKSLEDNLFPAIGKRSIDSFSTRDLLVPIKVVEATGRLE
VASRLQQRTNAIMRCAVQSGLIDYNPAQEMAGAVASSNRVHRPALELKRLPELLQRIDSYSGRPLTRLAVELTLLIFIRS
SELRFARWPEIDFERAMWTIPAEREAIEGVKHSERGSKMRTPHLVPLSRQALAILKQVHKLSGERDFVFVGDHNPCKPMS
ENTVNKALRVMGYDTKIEVCGHGFRTMACSSLIESGLWSRNAVERQMSHMERNSVRAAYIHKAQHLDERKMMLQWWADFL
DVNRVKGVSPFDFAKEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
intB CAD42017.1 bacteriophage P4 integrase Not tested PAI II 536 Protein 4e-148 76
ECO111_3718 YP_003236059.1 putative integrase Not tested LEE Protein 8e-141 67
c5216 NP_757064.1 prophage P4 integrase Not tested PAI II CFT073 Protein 2e-143 67
APECO1_3534 YP_854214.1 P4-like integrase Not tested PAI I APEC-O1 Protein 7e-144 67
S4822 NP_838459.1 P4-type integrase Not tested SHI-1 Protein 6e-144 67
SF2964 NP_708738.1 P4-type integrase Not tested SHI-1 Protein 6e-144 67
ORF_1 AAZ04412.1 phage integrase Not tested PAI I APEC-O1 Protein 5e-144 67
int AAK00456.1 Int Not tested SHI-1 Protein 1e-134 67
int AAK16198.1 Int Not tested PAI-I AL862 Protein 8e-143 67
int ADD91747.1 P4 integrase Not tested PAI-I AL862 Protein 8e-143 67
int-phe AAL60261.1 Int-phe Not tested LEE Protein 9e-142 66
ECO26_5300 YP_003232178.1 integrase Not tested LEE Protein 1e-141 66
int AAL51003.1 CP4-like integrase Not tested LEE Protein 9e-142 66
intP4 CAE85151.1 CP4 integrase protein Not tested PAI V 536 Protein 1e-142 66
ECUMN_3322 YP_002414004.1 integrase Not tested Not named Protein 3e-140 66
int AAT48697.1 CP4-like integrase Not tested PAI I 4787 Protein 1e-141 66
int-phe AAL57571.1 CP4-like integrase Not tested LEE Protein 9e-142 66
c3556 NP_755431.1 prophage P4 integrase Not tested PAI I CFT073 Protein 2e-141 66
int AAL51028.1 CP4-like integrase Not tested LEE Protein 9e-142 66
ECO103_3550 YP_003223418.1 integrase Not tested LEE Protein 1e-141 66
int CAC81896.1 integrase Not tested LEE II Protein 2e-132 66
Z4313 NP_289539.1 pathogenicity island integrase Not tested OI-122 Protein 6e-141 65
SESS1296_03598 AFO66301.1 bacteriophage integrase Not tested SESS LEE Protein 9e-128 60
SESS1635_03816 AFO66367.1 bacteriophage integrase Not tested SESS LEE Protein 9e-128 60
APECO1_1051 YP_853069.1 phage integrase Not tested PAI IV APEC-O1 Protein 2e-81 56
STY4821 NP_458899.1 integrase Not tested SPI-10 Protein 9e-119 55
int CAA08754.1 integrase Not tested HPI Protein 1e-110 54
intB AAD37509.1 P4-like integrase Not tested PAI IV 536 Protein 1e-93 54
int CAB59974.1 integrase Not tested HPI Protein 4e-111 53
int YP_002346908.1 integrase Not tested HPI Protein 5e-110 53
y2393 NP_669700.1 prophage integrase Not tested HPI Protein 5e-110 53
int2 NP_993013.1 integrase Not tested HPI Protein 5e-110 53
int CAA21384.1 - Not tested HPI Protein 5e-110 53
int NP_458759.1 bacteriophage integrase Not tested SPI-7 Protein 3e-114 53
int NP_807963.1 bacteriophage integrase Not tested SPI-7 Protein 3e-114 53
unnamed AAD17660.1 unknown Not tested HPI Protein 6e-107 52
unnamed ABR13507.1 phage integrase Not tested PAGI-6 Protein 1e-106 52
int ACU09430.1 integrase Not tested LEE Protein 6e-82 43
intL NP_290239.1 integrase for prophage 933L and the LEE pathogenicity island Not tested LEE Protein 8e-82 43
ECs4534 NP_312561.1 integrase Not tested LEE Protein 8e-82 43
int AAC31482.1 CP4-like integrase Not tested LEE Protein 6e-82 43
int AAD44730.1 Int Not tested SHI-2 Protein 3e-83 43
int CAC39282.1 integrase Not tested LPA Protein 3e-83 43
aec33 AAW51716.1 Int Not tested AGI-3 Protein 2e-83 43
ESA_03025 YP_001439090.1 hypothetical protein Not tested Not named Protein 4e-78 42
S4835 NP_839238.1 integrase Not tested SHI-2 Protein 1e-81 42
SF3698 NP_709437.1 integrase Not tested SHI-2 Protein 1e-81 42
int AAD54663.1 Sai integrase Not tested SHI-2 Protein 9e-82 42
unnamed AFX83955.1 integrase Not tested SE-PAI Protein 7e-74 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EC042_4741 YP_006098991.1 integrase VFG1536 Protein 3e-148 76
EC042_4741 YP_006098991.1 integrase VFG0626 Protein 2e-144 67
EC042_4741 YP_006098991.1 integrase VFG1693 Protein 8e-142 66
EC042_4741 YP_006098991.1 integrase VFG0783 Protein 3e-82 43
EC042_4741 YP_006098991.1 integrase VFG0598 Protein 5e-82 42