Gene Information

Name : EC042_4548 (EC042_4548)
Accession : YP_006098825.1
Strain : Escherichia coli 042
Genome accession: NC_017626
Putative virulence/resistance : Unknown
Product : hypothetical protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 4881858 - 4883645 bp
Length : 1788 bp
Strand : +
Note : Note that the product of this CDS is similar to many proposed UvrD helicases. However, the level of similarity to the originally described UVRD_ECOLI helicase in low, but protein motif searches do appear to support this idea.

DNA sequence :
ATGGCGAAACTGATAAATGTATCGGCGTCCACTGAGGAGAGAATGACGCCCGGGGAGAGGAGGGTAGCTTCACGACTGGA
GAGCTTTCTGAATGATGACTGCCTTGTCTGGTACGATATTCCGGTGGGACGGAAAAACCGGCATCCGGATTTTGTCATTA
TTGACCCGGAGAACGGACTGGTATTTCTGGAGGTCAAGGACTGGACGGTTTCCACGCTGCGCCAGGTAAATCAGGAGCAG
GTCACGCTGGAAACCGACGGTCTTCTGAAATCAGAAATCAATCCGCTGGTACAGGTTCGTCGTTATGCCTGTGATACGGT
TAATGCCTTACCTGCAAACCCGTGCTTACGGCAGAATGACGGTCAGTATAAGGGACGGCTGAACCTGGCCTGGGCGTATG
GTGTGGTGTTTACCCGCATTACCCGTCAGCAACTGAAGACACTGGCAGGGAATGATGAGAATGCGGTGGAAAAAATTTTT
CCTTCAGCACAGACAATCTGCCAGGATGAAATGACGCAGTCTGTTTTACCTGAAGTATTCCGGCAAAAAATTGCCGGGAT
GTTTACCACGGGATTCAGAACCCGGGTGACACCCCGGATGAGAGATATTCTGCGCGCCCATCTGTTTCCTGAAGTGACCG
TGAAACAGAACTCACAAATCAAAATTATGGATATTCAGCAGGAGATTCTGGCCAGAAATATTGGTGACGGGCATCGTGTC
ATTCATGGTGTGGCCGGTTCCGGAAAAACCATGATTCTTTTGTTCCGTTGCCTTTACCTGGCTGAAACCACACCCGGAAA
GATTCTGGTGTTGTGCTACAACATTACCCTGGCCAGCTATCTGCGGGAATGCATTGAAGCCAGAGGGCTGGCGTCACGGG
TTACGGTATCCCATTTTCACAGCTGGTGTGCCTCAATGGTAAAACGCCACGGTATTAAGGTGACGGCCGACAGAAAAGAA
TATCCTGATAAATGCTTCAGTACACTGGAAGAGGCCGTGAACAGCGGAAAAATCACCCGAACCGGATATGATGCTGTACT
GGTGGATGAGGGGCATGATTTTGACAGTCGCTGGCTGGCCCTGATTGCCCGTCTGTTTGATAACGCATCCCGTTCACTGC
TCCTGATGTACGATGACGCCCAGTCCATTTACCGGCGGGAGCGGGCCCTGAACTTTTCTCTGGCCAGTGTGGGGATTCAG
GCACAGGGACGCACTTCTGTCCTGCCGGTCAATTATCGTAATCCGAAACGCATTCTGCACTTTGCTTATGCATTCTCCCG
CGAGTATTTTGAAAAACATCAGAACCGTGAAATACCGCTCGTTCAGCCACAGGCGGGCGGTGAAGAGGGTACAGAGCCGG
AAATCCTGCGTTGTGCTTCTGAACGTGATGAAGCCAGACAAGTTGCAGACTGGCTGGAGAAGCGCCATGTCCTGTGTGGT
CACTGGAGTGATATGGCTGTGCTGTGTCCGACAGAGCGTTCAGCGCAACAATTGCAGGACGTTATGACACTACGCGGGGT
ACCTTTTGCCACCTGTTTTGACAGGGAAGGCAAGAAGACATACTCGCGACGTAAGGATGTGGTGCATTTACTGACGTACC
AGAGCAGCAAGGGGCTGGAGTTCCCGTATGTGGCGGTTATCAATGCGTCTTTCGTGCACTCTGGTGCAGCGGATGAGTCT
GAAGTGATTCCGGTGCTTTATGTGGCGTTCACCCGGGCAACCCGTGAATTACTGGTGACCTGTTACCGTGAAAACAGTAT
CAGTCGCCACCTTGAGGATTTTGCATAA

Protein sequence :
MAKLINVSASTEERMTPGERRVASRLESFLNDDCLVWYDIPVGRKNRHPDFVIIDPENGLVFLEVKDWTVSTLRQVNQEQ
VTLETDGLLKSEINPLVQVRRYACDTVNALPANPCLRQNDGQYKGRLNLAWAYGVVFTRITRQQLKTLAGNDENAVEKIF
PSAQTICQDEMTQSVLPEVFRQKIAGMFTTGFRTRVTPRMRDILRAHLFPEVTVKQNSQIKIMDIQQEILARNIGDGHRV
IHGVAGSGKTMILLFRCLYLAETTPGKILVLCYNITLASYLRECIEARGLASRVTVSHFHSWCASMVKRHGIKVTADRKE
YPDKCFSTLEEAVNSGKITRTGYDAVLVDEGHDFDSRWLALIARLFDNASRSLLLMYDDAQSIYRRERALNFSLASVGIQ
AQGRTSVLPVNYRNPKRILHFAYAFSREYFEKHQNREIPLVQPQAGGEEGTEPEILRCASERDEARQVADWLEKRHVLCG
HWSDMAVLCPTERSAQQLQDVMTLRGVPFATCFDREGKKTYSRRKDVVHLLTYQSSKGLEFPYVAVINASFVHSGAADES
EVIPVLYVAFTRATRELLVTCYRENSISRHLEDFA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
S12 AAQ19135.1 putative UvrD/REP helicase Not tested PAI I CL3 Protein 0.0 99
uvrD ADD91733.1 putative uvrD/REP helicase Not tested PAI-I AL862 Protein 0.0 96