Gene Information

Name : EC042_3069 (EC042_3069)
Accession : YP_006097364.1
Strain : Escherichia coli 042
Genome accession: NC_017626
Putative virulence/resistance : Virulence
Product : type III secretion system protein
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 3267542 - 3268861 bp
Length : 1320 bp
Strand : -
Note : -

DNA sequence :
ATGTCTTGCGATATGGAGCATGCTGGTATGAAAAAATTAAAACTATTAAATAAATACAGCTACTTACATAGCATAAACGG
CTCGCTGATTGAAGCAGAGCTTGACGACGTTTCAGTGGGCGAAGTATGCGAAATTTATGCGAGCTGGCAAGCAAATGAAC
GTATAGCCAGGGCTCAGGTCGTTGGCTTTCGCAATGGAAAGACATTATTAAACCTTATAGGCAGCTCTGTGGGGCTTACA
CGTACTGCAGTTTTGAAACCAACGGGAGAGCAATTAACCATACAGATCAATGATGCCTTTCTTGGTTCAGTTTTGAATGC
TTCTGGTCAAATTATGGAAAGGTTTGTCCCGGACACTCCAGGCGAAAGGGGAAATTTACGCCTGATTGATGAACTGCCAC
CGTCGTATAAGGAACGTCGAGTTATTAATACACCACTAGAGACACGGATAAGAGTCATTGATGGCGTACTGACATGTGGC
ATTGGTCAACGTGTTGGGATTTTCGCATCGGCTGGCTGTGGCAAAACGGTTTTAATGCATATGCTTGTAAACAACACTGA
AGCTGATGTGTTTGTTATTGGCTTGATTGGCGAACGTGGAAGGGAAGTTACGGAATGCGCGGAATCGCTGAAAAAATCAG
TAAATGCAGCAAAATGTGTTTTGGTTTATGCCACCTCTGATTTTTCGTCAGTAGATCGGTGTAATGCCGCCCTGATGGCG
ACAACCGTGGCAGAGTATTTTAGAGATCGAGGAAAGAGAGTTGTACTTTTTATCGACTCAATGACGCGCTATGCACGAGC
ACTACGCGATATGAAGCTGGCAGCGGGTGAACCACCTGCCAGACGTGGTTATCCTGCTTCTGTTTTTGACAGTTTACCTC
GCTTACTGGAGAGACCGGGACCAACGCTAAAAGGAAGTATTACTGCCTTTTATACCGTATTACTGGAGGGGGAGGATGAA
TCAGACCCACTGGGTGATGAAATTCGCTCAATCCTTGATGGCCATATCTATCTAAGTCGCAAACTCGCTGGGCAAGGTCA
TTATCCGGCAATAGATGTTCTAAAAAGTGTGAGTCGAGTATTTGGTCAGGTCACTGATGAAAAACACAGAGATAATGCTG
CACGGGTAAGGAAGATCCTCACAACTTTGGAAGAACTACAGGTGTTTATTGATTTAGGGGAATATCGCGCTGGGCAAAAT
GCTGAAAATGATTTTGCTATGAATGCCCGGCCTAAACTCACAAATTGGTTAAAACAGTCAGTTAATGAAAAAATGCCAAT
GAGTGAAACGCTAAAAGAGCTTGAACGAATTGTTAAGTAA

Protein sequence :
MSCDMEHAGMKKLKLLNKYSYLHSINGSLIEAELDDVSVGEVCEIYASWQANERIARAQVVGFRNGKTLLNLIGSSVGLT
RTAVLKPTGEQLTIQINDAFLGSVLNASGQIMERFVPDTPGERGNLRLIDELPPSYKERRVINTPLETRIRVIDGVLTCG
IGQRVGIFASAGCGKTVLMHMLVNNTEADVFVIGLIGERGREVTECAESLKKSVNAAKCVLVYATSDFSSVDRCNAALMA
TTVAEYFRDRGKRVVLFIDSMTRYARALRDMKLAAGEPPARRGYPASVFDSLPRLLERPGPTLKGSITAFYTVLLEGEDE
SDPLGDEIRSILDGHIYLSRKLAGQGHYPAIDVLKSVSRVFGQVTDEKHRDNAARVRKILTTLEELQVFIDLGEYRAGQN
AENDFAMNARPKLTNWLKQSVNEKMPMSETLKELERIVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ECs3730 NP_311757.1 ATP synthase SpaL Not tested LIM Protein 0.0 99
spaI NP_457288.1 secretory apparatus ATP synthase (associated with virulence) Virulence SPI-1 Protein 1e-131 65
spaI NP_806497.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-131 65
invC NP_461815.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-131 65
invC YP_217813.1 ATP synthase SpaL Virulence SPI-1 Protein 1e-131 65
invC AAS66861.1 InvC Not tested SSR-2 Protein 3e-121 60
ysaN AAS66842.1 YsaN Not tested SSR-1 Protein 1e-105 55
ssaN CAA70537.1 secretion system apparatus Virulence SPI-2 Protein 3e-73 46
ssaN YP_216423.1 type III secretion system ATPase Virulence SPI-2 Protein 1e-72 46
ssaN NP_460380.1 type III secretion system ATPase Virulence SPI-2 Protein 4e-73 46
ssaN NP_456113.1 putative type III secretion ATP synthase Virulence SPI-2 Protein 3e-72 46
ssaN NP_805086.1 type III secretion system ATPase Virulence SPI-2 Protein 3e-72 46
lscN AAO18044.1 LscN Virulence TTSS locus Protein 7e-82 45
hrcN AAR25633.1 type III secretion cytoplasmic ATPase HrcN Not tested Not named Protein 2e-62 45
escN AAC38383.1 EscN Virulence LEE Protein 2e-70 45
escN NP_290268.1 hypothetical protein Virulence LEE Protein 1e-70 45
escN AAC31513.1 L0034 Virulence LEE Protein 1e-70 45
ECs4568 NP_312595.1 EscN Virulence LEE Protein 1e-70 45
unnamed ACU09458.1 type III secretion apparatus H+-transporting two-sector ATPase Virulence LEE Protein 1e-70 45
hrcN AAG33879.1 HrcN Virulence Hrp PAI Protein 8e-69 44
hrpB6 AAB08461.1 HrpB6 Virulence Hrp PAI Protein 2e-75 44
hrcN YP_362163.1 type III secretion system ATPase Virulence Hrp PAI Protein 2e-75 44
hrpB6 BAB07852.1 HrpB6 Virulence Hrp PAI Protein 9e-77 44
hrcN YP_198730.1 type III secretion system ATPase Virulence Hrp PAI Protein 1e-76 44
hrpB6 AAF61281.1 HrpB6 Virulence Hrp PAI Protein 9e-77 44
hrcN AAP34339.1 HrcN Virulence Hrp PAI Protein 9e-77 44
hrcN NP_640767.1 type III secretion system ATPase Virulence Hrp PAI Protein 4e-76 44
XC_3006 YP_244074.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-77 44
hrcN NP_636610.1 type III secretion system ATPase Virulence Hrp PAI Protein 6e-77 44
hrcN NP_791227.1 type III secretion cytoplasmic ATPase HrcN Virulence Hrp PAI Protein 9e-69 44
escN CAC81862.1 EscN protein Virulence LEE II Protein 6e-70 44
escN YP_003223475.1 translocator EscN Virulence LEE Protein 2e-69 44
escN YP_003232153.1 T3SS structure protein EscN Virulence LEE Protein 8e-70 44
escN AAK26715.1 EscN Virulence LEE Protein 2e-69 44
escN AAL57542.1 EscN Virulence LEE Protein 2e-69 44
escN YP_003236088.1 translocator EscN Virulence LEE Protein 1e-70 44
escN CAI43874.1 EscN protein Virulence LEE Protein 1e-69 44
unnamed AAL06369.1 EscN Virulence LEE Protein 8e-70 44
YPO0267 YP_002345348.1 type III secretion system ATPase Virulence Not named Protein 7e-72 43
escN AFO66300.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-67 43
escN AFO66415.1 putative LEE-encoded type III secretion system ATPase Virulence SESS LEE Protein 1e-67 43
hrcN AAT96141.1 HrcN Virulence T-PAI Protein 3e-70 43
hrcN AAT96195.1 HrcN Virulence T-PAI Protein 6e-70 43
hrcN AAB06001.1 HrcN Virulence Hrp PAI Protein 1e-66 43
hrcN ABQ88354.1 HrcN Virulence Hrp PAI Protein 1e-63 42
hrpJ4 AAA81942.1 HrpJ4 Virulence Hrp PAI Protein 1e-63 42
hrcN ABA47275.1 HrcN Virulence S-PAI Protein 8e-76 42
hrcN AAT96339.1 HrcN Virulence S-PAI Protein 8e-71 42
hrcN AAT96299.1 HrcN Virulence S-PAI Protein 4e-71 42
hrcN AAT96258.1 HrcN Virulence S-PAI Protein 3e-71 42

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
EC042_3069 YP_006097364.1 type III secretion system protein VFG0555 Protein 4e-132 65
EC042_3069 YP_006097364.1 type III secretion system protein VFG1008 Protein 5e-114 60
EC042_3069 YP_006097364.1 type III secretion system protein VFG2459 Protein 2e-115 58
EC042_3069 YP_006097364.1 type III secretion system protein VFG1778 Protein 2e-105 57
EC042_3069 YP_006097364.1 type III secretion system protein VFG0390 Protein 2e-83 47
EC042_3069 YP_006097364.1 type III secretion system protein VFG0192 Protein 9e-85 47
EC042_3069 YP_006097364.1 type III secretion system protein VFG2144 Protein 4e-75 46
EC042_3069 YP_006097364.1 type III secretion system protein VFG0515 Protein 2e-73 46
EC042_3069 YP_006097364.1 type III secretion system protein VFG0812 Protein 6e-71 45
EC042_3069 YP_006097364.1 type III secretion system protein VFG0730 Protein 1e-70 45
EC042_3069 YP_006097364.1 type III secretion system protein VFG0048 Protein 3e-79 43
EC042_3069 YP_006097364.1 type III secretion system protein VFG2331 Protein 2e-58 43
EC042_3069 YP_006097364.1 type III secretion system protein VFG2499 Protein 1e-59 42
EC042_3069 YP_006097364.1 type III secretion system protein VFG1254 Protein 2e-64 41