Gene Information

Name : topB (EC042_1929)
Accession : YP_006096239.1
Strain : Escherichia coli 042
Genome accession: NC_017626
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : -
COG ID : -
EC number : 5.99.1.2
Position : 2016824 - 2018770 bp
Length : 1947 bp
Strand : -
Note : -

DNA sequence :
ATGCGGTTGTTTATTGCCGAAAAACCGAGTCTGGCGCGCGCCATTGCTGATGTCCTGCCCAAACCGCACCGGAAAGGCGA
TGGCTTTATCGAGTGCGGTAATGGTCAGGTAGTGACCTGGTGTATCGGTCACCTGCTTGAGCAGGCGCAGCCAGACGCCT
ACGACAGCCGCTATGCGCGCTGGAATCTTGCGGATTTGCCGATTGTCCCGGAAAAGTGGCAATTACAGCCCCGACCCTCC
GTGACTAAACAACTTAATGTCATCAAACGCTTCCTGCATGAAGCCAGCGAAATCGTTCACGCCGGTGACCCGGATCGCGA
AGGGCAATTACTGGTGGATGAAGTGCTGGACTATCTGCAACTGGCACCGGAAAAGCGCCAGCAGGTGCAGCGTTGCTTGA
TAAACGACCTGAACCCGCAGGCGGTTGAGCGGGCGATCGATCGTCTTCGTTCCAACAGTGAGTTTGTGCCGTTGTGCGTT
TCTGCACTGGCGCGAGCCCGAGCCGACTGGCTGTACGGAATCAATATGACCCGCGCTTACACCATTCTCGGTCGCAATGC
GGGTTATCAGGGCGTGCTTTCCGTGGGACGCGTGCAGACGCCCGTGCTCGGGCTGGTAGTGCGCCGCGACGAAGAGATTG
AAAACTTCGTGGCGAAAGACTTCTTTGAAGTCAAAGCACATATCGTGACACCTGCCGATGAGCGGTTTACCGCTATCTGG
CAACCGAGCGAAGCGTGTGAACCGTACCAGGATGAAGAAGGGCGCTTGTTACATCGTCCACTGGCGGAGCATGTGGTTAA
CCGCATTAGTGGTCAACCGGCTATAGTCACCAGCTATAACGATAAACGGGAATCAGAATCCGCACCGCTGCCGTTTTCGC
TTTCGGCGTTGCAGATTGAAGCGGCAAAACGCTTTGGTCTGAGTGCGCAGAACGTGCTTGATATCTGCCAGAAGTTGTAC
GAAACGCACAAGCTAATCACTTATCCGCGTTCCGATTGTCGCTATCTGCCGGAAGAGCATTTTGCCGGACGCCACGCAGT
GATGAATGCCATCAGCGTTCATGCACCGGGGTTGTTACCGCAGCCAGTGGTCGATCCAGATATACGCAACCGCTGCTGGG
ATGACAAAAAGGTCGATGCGCACCACGCCATCATCCCGACCGCACGGAGTTCTGCGATCAACCTGACGGAGAACGAATCG
AAGGTCTATAACCTGATTGCTCGTCAATACCTGATGCAGTTCTGCCCGGATGCGGTGTTCCGCAAGTGTGTTATCGAACT
GGAAATAGCCAAAGGTAAATTTGTCGCTAAAGCCCGTTTTCTTGCCGAAGCAGGCTGGCGCACGCTGTTAGGCAGCAAAG
AGCGCGATGAAGAAAACGATGGCACGCCGCTGCCTGTGGTGGCGAAAGGCGATGAGTTGCTGTGTGAAAAAGGTGAAGTG
GTAGAGCGGCAAACGCAGCCGCCGCGCCATTTTACCGATGCAACACTGCTTTCGGCGATGACCGGGATCGCGCGCTTTGT
GCAGGACAAAGATCTGAAAAAGATCCTCCGTGCTACCGATGGTCTGGGGACAGAAGCAACACGTGCCGGGATTATTGAAC
TGTTGTTCAAGCGTGGTTTCCTGACCAAAAAAGGGCGCTATATCCACTCCACCGACGCTGGAAAAGCGTTATTCCATTCG
CTGCCGGAGATGGCAACGAGACCGGACATGACCGCGCACTGGGAATCGGTGCTGACGCAAATCAGCGAAAAGCAGTGTCG
CTATCAGGACTTTATGCAGCCGTTGGTGGGGACGCTTTACCAACTGATTGATCAGGCTCGTAGCACTCCGGTCAGACGGT
TTAGAGGAATTGTGGCACCAGGTGGGGGGGCTGTTAAAAAAGCACCCAATAATCGTGTGAAAAAAGCGGCAAAGCCCAAA
AAAGATAATACGGATTCTGCTAATTAA

Protein sequence :
MRLFIAEKPSLARAIADVLPKPHRKGDGFIECGNGQVVTWCIGHLLEQAQPDAYDSRYARWNLADLPIVPEKWQLQPRPS
VTKQLNVIKRFLHEASEIVHAGDPDREGQLLVDEVLDYLQLAPEKRQQVQRCLINDLNPQAVERAIDRLRSNSEFVPLCV
SALARARADWLYGINMTRAYTILGRNAGYQGVLSVGRVQTPVLGLVVRRDEEIENFVAKDFFEVKAHIVTPADERFTAIW
QPSEACEPYQDEEGRLLHRPLAEHVVNRISGQPAIVTSYNDKRESESAPLPFSLSALQIEAAKRFGLSAQNVLDICQKLY
ETHKLITYPRSDCRYLPEEHFAGRHAVMNAISVHAPGLLPQPVVDPDIRNRCWDDKKVDAHHAIIPTARSSAINLTENES
KVYNLIARQYLMQFCPDAVFRKCVIELEIAKGKFVAKARFLAEAGWRTLLGSKERDEENDGTPLPVVAKGDELLCEKGEV
VERQTQPPRHFTDATLLSAMTGIARFVQDKDLKKILRATDGLGTEATRAGIIELLFKRGFLTKKGRYIHSTDAGKALFHS
LPEMATRPDMTAHWESVLTQISEKQCRYQDFMQPLVGTLYQLIDQARSTPVRRFRGIVAPGGGAVKKAPNNRVKKAAKPK
KDNTDSAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 4e-104 41
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 5e-112 41