Gene Information

Name : SSGZ1_1246 (SSGZ1_1246)
Accession : YP_006074645.1
Strain : Streptococcus suis GZ1
Genome accession: NC_017617
Putative virulence/resistance : Virulence
Product : suilysin
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 1296206 - 1297687 bp
Length : 1482 bp
Strand : -
Note : proposed virulence factor; in regions AI 78: Region of the GZ1 chromosome not homologous to 89/1591

DNA sequence :
ATGAGAAAAAGTTCGCACTTGATTTTAAGCTCAATAGTCAGTTTGGCACTCGTAGGGGTCACACCATTGAGTGTTCTTGC
AGATTCCAAACAAGATATTAATCAGTATTTTCAAAGCTTGACTTACGAGCCACAAGAGATTCTTACAAATGAGGGAGAAT
ACATTGATAATCCGCCAGCAACAACTGGTATGTTAGAAAACGGACGTTTTGTAGTACTTCGCAGAGAAAAGAAGAATATT
ACGAACAATAGTGCAGATATTGCTGTTATTGATGCTAAGGCTGCAAATATTTATCCAGGTGCTTTATTGCGTGCTGACCA
AAATCTTCTGGATAATAATCCAACGCTTATCAGTATTGCGCGGGGAGATCTGACGCTTAGTTTGAATTTACCTGGTTTGG
CCAATGGGGATAGCCACACTGTTGTAAATTCTCCAACAAGAAGTACTGTTCGAACAGGGGTGAATAACCTTCTGTCTAAA
TGGAATAATACGTATGCTGGAGAGTATGGCAATACCCAAGCAGAGCTTCAATATGATGAAACAATGGCATACAGTATGTC
ACAATTGAAAACGAAGTTCGGAACCTCTTTTGAAAAAATTGCTGTACCATTAGATATCAATTTTGATGCCGTGAATTCGG
GTGAAAAACAGGTTCAGATTGTTAACTTTAAACAAATTTATTATACAGTTAGTGTTGATGAACCAGAATCTCCAAGCAAG
CTTTTTGCAGAAGGGACAACTGTAGAAGATTTGAAACGAAATGGGATAACAGATGAGGTACCTCCTGTTTATGTTTCCAG
CGTTTCTTATGGACGCTCTATGTTCATCAAGTTAGAAACTAGCAGTAGGAGTACCCAAGTTCAAGCCGCATTTAAAGCAG
CCATCAAAGGCGTTGATATTAGTGGCAATGCTGAGTATCAAGACATTCTGAAAAATACTTCATTCTCTGCTTATATTTTT
GGTGGGGATGCAGGTAGCGCGGCTACTGTTGTGAGCGGAAATATTGAAACACTGAAGAAGATTATTGAAGAAGGTGCAAG
ATACGGAAAACTCAATCCAGGTGTTCCGATTTCGTATTCAACCAACTTTGTCAAAGACAATAGACCTGCTCAGATTTTGA
GCAATTCAGAGTACATAGAAACAACTTCAACAGTCCATAATAGCAGTGCATTGACATTGGATCATTCAGGTGCTTATGTT
GCGAAATACAACATTACTTGGGAAGAAGTATCTTACAATGAAGCTGGAGAAGAAGTTTGGGAACCAAAAGCTTGGGATAA
GAATGGTGTAAATCTGACCTCACACTGGAGTGAAACCATTCAAATTCCAGGAAATGCTCGCAATCTTCATGTCAATATTC
AAGAATGTACAGGATTAGCATGGGAGTGGTGGAGAACAGTTTATGACAAAGATTTACCACTTGTTGGTCAACGTAAAATA
ACCATCTGGGGGAACAACGTTATACCCACAGTATGCGGATGA

Protein sequence :
MRKSSHLILSSIVSLALVGVTPLSVLADSKQDINQYFQSLTYEPQEILTNEGEYIDNPPATTGMLENGRFVVLRREKKNI
TNNSADIAVIDAKAANIYPGALLRADQNLLDNNPTLISIARGDLTLSLNLPGLANGDSHTVVNSPTRSTVRTGVNNLLSK
WNNTYAGEYGNTQAELQYDETMAYSMSQLKTKFGTSFEKIAVPLDINFDAVNSGEKQVQIVNFKQIYYTVSVDEPESPSK
LFAEGTTVEDLKRNGITDEVPPVYVSSVSYGRSMFIKLETSSRSTQVQAAFKAAIKGVDISGNAEYQDILKNTSFSAYIF
GGDAGSAATVVSGNIETLKKIIEEGARYGKLNPGVPISYSTNFVKDNRPAQILSNSEYIETTSTVHNSSALTLDHSGAYV
AKYNITWEEVSYNEAGEEVWEPKAWDKNGVNLTSHWSETIQIPGNARNLHVNIQECTGLAWEWWRTVYDKDLPLVGQRKI
TIWGNNVIPTVCG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 2e-106 45
slo YP_281505.1 streptolysin O Virulence Not named Protein 4e-85 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SSGZ1_1246 YP_006074645.1 suilysin VFG1363 Protein 1e-114 50
SSGZ1_1246 YP_006074645.1 suilysin VFG0074 Protein 6e-107 45
SSGZ1_1246 YP_006074645.1 suilysin VFG2275 Protein 3e-93 41