Gene Information

Name : pyk (SPYALAB49_000976)
Accession : YP_006072128.1
Strain : Streptococcus pyogenes Alab49
Genome accession: NC_017596
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 958047 - 959549 bp
Length : 1503 bp
Strand : -
Note : -

DNA sequence : 
ATGAATAAACGCGTAAAAATCGTTGCAACACTTGGTCCTGCGGTTGAAATCCGTGGTGGTAAAAAATACGGAGAAGATGG
CTACTGGGCTGGTCAACTTGATGTTGAAGAATCAGCAAAAAAAATCGCTGAATTAATTGAAGCTGGTGCGAATGTTTTCC
GTTTCAATTTCTCACATGGTGACCACAAAGAACAAGGTGACCGTATGGCAACTGTTCGCCTTGCAGAAGAAATTGCTCGT
CAAAAAGTTGGTTTCCTTTTGGATACTAAAGGTCCTGAAATGCGTACGGAATTGTTTGCAGATGATGCTAAAGAATTCAG
CTATGTCACTGGAGAAAAAATCCGTGTAGCGACTACACAAGGTATTCAATCAACTCGCGATGTTATTGCTTTGAACGTTG
CTGGTAGCCTTGACATCTACGATGAAGTAGAAGTAGGTCATACTATTCTTATCGATGATGGTAAACTTGGTTTGAAAGTG
ATCGACAAAGATATCGCAACACGTCAATTTATCGTTGAAGTAGAAAACGATGGTATTATTGCTAAACAAAAAGGTGTTAA
TATCCCTAACACTAAAATTCCTTTCCCAGCACTTGCGGAACGCGACAATGCTGATATCCGTTTTGGTCTTGAACAAGGAC
TTAACTTTATTGCAATCTCATTTGTTCGTACAGCCAAAGACGTTGAGGAAGTTCGTGAAATCTGTCGCGAAACTGGTAAC
GATCATGTGCAATTATTTGCTAAGATTGAAAACCAACAAGGTATCGATAATCTTGATGAAATCATCGAAGCTGCTGATGG
TATCATGATTGCACGTGGCGACATGGGTATCGAAGTACCATTTGAAATGGTTCCAGTTTTCCAAAAAATGATTATCACTA
AAGTGAATGCAGCTGGTAAAGCAGTTATCACAGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCGACACGT
TCTGAAGTATCTGACGTCTTCAATGCTGTTATCGATGGTACTGATGCAACAATGCTTTCAGGAGAGTCAGCTAACGGTAA
ATACCCGGTTGAATCTGTTCGTACAATGGCGACTATTGATCGTAATGCACAAACTCTTCTTAACGAATATGGTCGTTTAG
ATTCATCTGCCTTCCCACGTACCAATAAAACAGATGTTATTGCTTCAGCTGTTAAAGATGCCACTCATTCAATGGACATC
AAACTTGTTGTGACTATTACTGAGACAGGTAATACAGCTCGTGCGATTTCTAAATTCCGTCCAGATGCGGATATCTTAGC
TGTAACATTTGATGAAAAAGTACAACGTGCTTTGATGATTAACTGGGGTGTTATTCCTGTTCTTGCTGAAAAACCTGCAT
CTACTGATGACATGTTTGAAGTAGCAGAGCGTGTTGCTGTGGAGGCAGGCTTAGTTCAATCTGGGGATAATATTGTTATT
GTTGCTGGTGTTCCAGTTGGTACTGGTGGAACGAATACTATGCGTGTTCGTACAGTAAAATAA

Protein sequence : 
MNKRVKIVATLGPAVEIRGGKKYGEDGYWAGQLDVEESAKKIAELIEAGANVFRFNFSHGDHKEQGDRMATVRLAEEIAR
QKVGFLLDTKGPEMRTELFADDAKEFSYVTGEKIRVATTQGIQSTRDVIALNVAGSLDIYDEVEVGHTILIDDGKLGLKV
IDKDIATRQFIVEVENDGIIAKQKGVNIPNTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVEEVREICRETGN
DHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVFQKMIITKVNAAGKAVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDRNAQTLLNEYGRLDSSAFPRTNKTDVIASAVKDATHSMDI
KLVVTITETGNTARAISKFRPDADILAVTFDEKVQRALMINWGVIPVLAEKPASTDDMFEVAERVAVEAGLVQSGDNIVI
VAGVPVGTGGTNTMRVRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 1e-80 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 5e-81 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 5e-81 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 3e-81 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006072128.1 pyruvate kinase VFG0479 Protein 2e-81 43