Gene Information

Name : slo (SPYALAB49_000180)
Accession : YP_006071346.1
Strain : Streptococcus pyogenes Alab49
Genome accession: NC_017596
Putative virulence/resistance : Virulence
Product : streptolysin O
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 152336 - 154060 bp
Length : 1725 bp
Strand : +
Note : -

DNA sequence :
ATGAAGGACATGTCTAATAAAAAAACATTTAAAAAATACAGTCGCGTCGCTGGGCTACTGACGGCAGCTCTTATCATTGG
TAACCTTGTTACTGCTAATGCTGAATCGAACAAACAAAACACTGCTAGTACAGAAACCACAACGACAAATGAGCAACCAA
AGCCAGAAAGTAGTGAGCTAACTACTGAAAAAGCAGGTCAGAAAACGGATGATATGCTTAACTCTAACGATATGATTAAG
CTTGCTCCCAAAGAAATGCCACTAGAATCTGCAGAAAAAGAAGAAAAAAAGTCAGAAGACAAAAAAAAGAGCGAAGAAGA
TCACACTGAAGAAATCAATGACAAGATTTATTCACTAAATTATAATGAGCTTGAAGTACTTGCTAAAAATGGTGAAACCA
TTGAAAATTTTGTTCCTAAAGAAGGCGTTAAGAAAGCTGATAAATTTATTGTCATTGAAAGAAAGAAAAAAAATATCAAC
ACTACACCAGTCGATATTTCCATTATTGACTCTGTCACTGATAGGACCTATCCAGCAGCCCTTCAGCTGGCTAATAAAGG
TTTTACCGAAAACAAACCAGACGCGGTAGTCACCAAGCGAAACCCACAAAAAATCCATATTGATTTACCAGGTATGGGAG
ACAAAGCAACGGTTGAGGTCAATGACCCTACCTATGCCAATGTTTCAACAGCTATTGATAATCTTGTTAACCAATGGCAT
GATAATTATTCTGGTGGTAATACGCTTCCTGCCAGAACACAATATACTGAATCAATGGTATATTCTAAATCACAGATTGA
AGCAGCTCTAAATGTTAATAGCAAAATCTTAGATGGTACTTTAGGCATTGATTTCAAGTCGATTTCAAAAGGTGAAAAGA
AGGTGATGATTGCAGCATACAAGCAAATTTTTTACACCGTATCAGCAAACCTTCCTAATAATCCTGCGGATGTGTTTGAT
AAATCAGTGACCTTTAAAGAGTTGCAACGAAAAGGTGTCAGCAATGAAGCTCCGCCACTCTTTGTGAGTAACGTAGCTTA
TGGTAGAACTGTTTTTGTCAAACTAGAAACAAGTTCTAAAAGTAATGATGTTGAAGCGGCCTTTAGTGCAGCTCTAAAAG
GAACAGATGTTAAAACGAATGGAAAATACTCTGATATCTTAGAAAATAGCTCATTTACAGCTGTCGTTTTAGGAGGAGAT
GCTGCAGAGCACAATAAGGTAGTCACAAAAGACTTTGATGTTATTAGAAACGTTATCAAGGACAATGCTACCTTCAGTAG
AAAAAACCCAGCTTATCCTATTTCATACACCAGTGTTTTCCTTAAAAATAATAAAATTGCGGGTGTCAATAACAGAACTG
AATACGTTGAAACAACATCTACCGAGTACACTAGTGGAAAAATTAACCTGTCTCACCAAGGCGCGTATGTTGCTCAATAT
GAAATCCTCTGGGATGAAATCAATTATGATGACAAAGGAAAAGAAGTGATTACAAAACGACGCTGGGACAACAACTGGTA
TAGTAAGACATCACCATTTAGCACAGTTATCCCACTAGGAGCTAATTCACGAAATATCCGTATCATGGCTAGAGAGTGCA
CCGGCTTAGCTTGGGAATGGTGGCGAAAAGTGATCGACGAAAGAGATGTGAAACTGTCTAAAGAAATCAATGTCAACATC
TCAGGATCAACCCTGAGCCCATATGGTTCGATTACTTATAAGTAG

Protein sequence :
MKDMSNKKTFKKYSRVAGLLTAALIIGNLVTANAESNKQNTASTETTTTNEQPKPESSELTTEKAGQKTDDMLNSNDMIK
LAPKEMPLESAEKEEKKSEDKKKSEEDHTEEINDKIYSLNYNELEVLAKNGETIENFVPKEGVKKADKFIVIERKKKNIN
TTPVDISIIDSVTDRTYPAALQLANKGFTENKPDAVVTKRNPQKIHIDLPGMGDKATVEVNDPTYANVSTAIDNLVNQWH
DNYSGGNTLPARTQYTESMVYSKSQIEAALNVNSKILDGTLGIDFKSISKGEKKVMIAAYKQIFYTVSANLPNNPADVFD
KSVTFKELQRKGVSNEAPPLFVSNVAYGRTVFVKLETSSKSNDVEAAFSAALKGTDVKTNGKYSDILENSSFTAVVLGGD
AAEHNKVVTKDFDVIRNVIKDNATFSRKNPAYPISYTSVFLKNNKIAGVNNRTEYVETTSTEYTSGKINLSHQGAYVAQY
EILWDEINYDDKGKEVITKRRWDNNWYSKTSPFSTVIPLGANSRNIRIMARECTGLAWEWWRKVIDERDVKLSKEINVNI
SGSTLSPYGSITYK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
slo YP_281505.1 streptolysin O Virulence Not named Protein 0.0 99
hly AAA69525.1 listeriolysin O Virulence LIPI-1 Protein 8e-93 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
slo YP_006071346.1 streptolysin O VFG0976 Protein 0.0 100
slo YP_006071346.1 streptolysin O VFG2275 Protein 3e-150 67
slo YP_006071346.1 streptolysin O VFG1363 Protein 2e-91 43
slo YP_006071346.1 streptolysin O VFG0074 Protein 5e-93 42