Gene Information

Name : cadA (SPYALAB49_001166)
Accession : YP_006072317.1
Strain : Streptococcus pyogenes Alab49
Genome accession: NC_017596
Putative virulence/resistance : Unknown
Product : cadmium-translocating P-type ATPase
Function : -
COG functional category : -
COG ID : -
EC number : 3.6.3.-
Position : 1129196 - 1131058 bp
Length : 1863 bp
Strand : -
Note : -

DNA sequence :
ATGACAATCAGACAATGGATGGCAGACCATCTTCATTTAATGGAGACTTTAGCGTGTTTGGTATTAATAATAATTGGCCT
AGCCTTTTTACACTCATTTCCACAAGTGGCTTCCGCTATTTTCATTACAGCCTACTTGATTGGAGGATATGCGTCTGCAA
AAACGGGTATATTGGATTTGGTGAAGAACAAACACTTGTCAGTGGATATTTTGATGATTTTGGCAGCTATCGGTGCTGGA
ATTATCGGCTATTGGCTGGAGGGTGCTCTGCTTATTTTTATCTTTTCGTTGTCCAATACGCTTGAAGAAATGGCCATGGA
AAAAAGTAAGGATGCTATTTCAGGCTTGATGTCCTTGACGCCAGATACAGCTCGTCAATACCAAGAAGATGGCCATATTT
TAGAAGTTGAGACCAGATCCTTGAGTGTTGGTGACCGTTTACAAGTTCGTAAAGGCGAAGCTGTTCCAATTGACGGGCAG
TTGCTTAGTCCTTTTGGTCAATTTGATGAATCTATGGTCACTGGTGAGCCTATCACTGTTGATAAGGCAGAAGGCCAGGA
TCTGATTGGGGGAACCATTAACCAAGGACAAACCATAGATATGTTGGTTACTATTGAAAATGACAATACTCTCTTTGCCA
AGATTATTAATCTGGTGGAATCTGCCCAAGAAAAGAAAAGCAAAACCGCCACCTTTATCGAAAGCTTAGAAGATGGTTAT
GTCAAATTTGTGCTCGTCCTTATTCCTGCCTTTATCCTCTTTAGCCACTTTGTGCTTTCTTGGACTTGGTTGGCTGCTTT
TTACCGAGGGATGATTCTCTTAACAGTAGCTTCACCATGTGCCCTAATTGCCAGTTCCACACCTGCTAGCTTGGCTGCTA
TTTCTCGTGCAGCCAGGAAGGGATTGATTATCAAAGGAGGGGATATTGTCGATAACATGGGAGATATTAAGGCTGTTGTC
ATGGATAAAACGGGAACACTCACCCAAGGAAAACCTTCTGTTGTGAATGCTCATTATTTGGAAGATGAGTTGCTCGTGAA
TAGACTGGTAAAAGGAGCAGAGGCTGCTAGTACCCATCCTATTTCTAAAGCCTTTCTTGAATACACTGAAAAATTGGAGC
CACTGACCTTTGACCACTTAGAAGAAATTTCTGGGAAAGGTTTTCAGGGCTTCTATCAAGGGCAAGAATGGCGCATTGGG
AAGAAATCCTTTATTTTAGAGATGGTGCCAGATCTTTCAGCTTTTGAAGAAACGATTCAGGTAGAAGAAAGTCAAGGGAA
AACTCTTATCTTTGTTTCTCGCGACAACCAACTAGTAGCCTACTACGCTTTGTTAGATGACATCAAATTAGAGTCAAAAC
GTGCCATTGAAGCTCTTCATGCTATGGGAATCAAGACGGTCATGTTAACAGGGGACCAAGAACGAACTGCCAATTATGTG
GCACAAAAACTTGGTATTGATGAAGTGGTAGCCAACTGTATGCCTCAAGATAAGGTGGCTAAGTTAGCAGAATTAAAGAC
CAAATATGGTTTTGTGGCCATGGTAGGAGATGGTATTAATGATGCTCCTGCCCTTGCTCAAGCAGATGTTTCTTATGCTA
TTGGATCAGGAACAGATATTGCAATGGAAAGTGCAGACAGTGTGATTATGGATGACTTGACTCGTATTCCATTTTCGATT
CAACTTTCCCGCAAAATGAAGACCATTATCAAACAAAATATTGTTTTTGCCTTATCTGTGATTACCTTATTGATTTTAGC
CAATGTTTTTCAGGTAGTTAACTTGCCGCTTGGTGTTGTTGGACACGAAGGCTCAACGATTTTAGTGATTTTAAATGGCT
TGCGTTTACTTTCTTTTAAATAA

Protein sequence :
MTIRQWMADHLHLMETLACLVLIIIGLAFLHSFPQVASAIFITAYLIGGYASAKTGILDLVKNKHLSVDILMILAAIGAG
IIGYWLEGALLIFIFSLSNTLEEMAMEKSKDAISGLMSLTPDTARQYQEDGHILEVETRSLSVGDRLQVRKGEAVPIDGQ
LLSPFGQFDESMVTGEPITVDKAEGQDLIGGTINQGQTIDMLVTIENDNTLFAKIINLVESAQEKKSKTATFIESLEDGY
VKFVLVLIPAFILFSHFVLSWTWLAAFYRGMILLTVASPCALIASSTPASLAAISRAARKGLIIKGGDIVDNMGDIKAVV
MDKTGTLTQGKPSVVNAHYLEDELLVNRLVKGAEAASTHPISKAFLEYTEKLEPLTFDHLEEISGKGFQGFYQGQEWRIG
KKSFILEMVPDLSAFEETIQVEESQGKTLIFVSRDNQLVAYYALLDDIKLESKRAIEALHAMGIKTVMLTGDQERTANYV
AQKLGIDEVVANCMPQDKVAKLAELKTKYGFVAMVGDGINDAPALAQADVSYAIGSGTDIAMESADSVIMDDLTRIPFSI
QLSRKMKTIIKQNIVFALSVITLLILANVFQVVNLPLGVVGHEGSTILVILNGLRLLSFK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cadA YP_005732869.1 cadmium-translocating P-type ATPase Not tested Type-V SCCmec Protein 3e-91 41
SE0062 NP_763617.1 copper-transporting ATPase copA Not tested SCCpbp4 Protein 2e-91 41