Gene Information

Name : pyk (SALIVA_0892)
Accession : YP_006070047.1
Strain : Streptococcus salivarius JIM8777
Genome accession: NC_017595
Putative virulence/resistance : Virulence
Product : pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 898068 - 899570 bp
Length : 1503 bp
Strand : +
Note : -

DNA sequence :
ATGAATAAACGTGTAAAAATCGTTGCAACACTTGGTCCTGCGGTTGAAATCCGTGGCGGCAAAAAATTTGGTGAAGATGG
TTACTGGGGTGAAAAACTTGACCGTGAAGCATCTGCTAAAAACATTGCTCAATTGATCAAGGAAGGTGCCAACGTTTTCC
GTTTCAACTTCTCACATGGTGACCACGCTGAACAAGGTGAACGTATGGATGTCGTTCGTATGGCAGAAGACCTTGCTGGT
CAAAAAGTAGGTTTCCTTCTTGATACAAAAGGACCTGAAATCCGTACTGAATTGTTCGAAGGTGATGCTAAAGAGTATGC
ATACAAAACTGGTGAACAAATTCGTGTTGCTACTAAACAAGGTATCAAATCAACTCGCGACGTTATCGCTTTGAACGTTG
CAGGTGCACTTGACGTTTTTGACGATGTAGAAGTTGGTAAACAAGTTCTTGTCGATGATGGTAAACTTGGTCTTCGTGTT
GTAGACAAAGATGCTGAAAAACGTGAATTCATCGTTGAAGTTGAAAATGATGGTATCATCGCTAAACAAAAAGGTGTAAA
CATCCCTTACACTAAAATTCCTTTCCCAGCACTTGCTGAACGTGATAACGCTGATATCCGTTTTGGTCTTGAACAAGGTC
TTAACTTTATCGCTATCTCATTCGTACGTACTGCAAAAGACGTACAAGAAGTTCGTGCTATCTGTGAAGAAACTGGTAAC
GGTCACGTTCAATTGTTGGCTAAAATCGAAAACCAACAAGGTATCGATAACATCGATGAAATCATCGAAGCTGCTGACGG
TATCATGATCGCTCGTGGTGACATGGGTATCGAAGTACCATTCGAAATGGTTCCAGTTTACCAAAAAATGATCATCACTA
AAGTAAACGCTGCTGGTAAGGTTGTTGTTACAGCTACTAACATGCTTGAAACAATGACAGAAAAACCACGTGCAACTCGT
TCTGAAGTATCTGACGTATTCAACGCAGTTATCGATGGTACAGATGCTACAATGCTTTCTGGTGAGTCTGCAAATGGTAA
ATACCCAGTTGAATCAGTTCGTACAATGGCTACAATTGATAAAAACGCTCAAACTCTTCTTAAAGAGTATGGTCGTCTTG
ATTCATCAACATTTGACCGTTCAACTAAGACTGAAGTTGTTGCGTCTGCAGTTAAAGATGCTACTAACTCAATGGATATC
AAACTTGTTGTTGCTCTTACTGAATCAGGTAACACTGCTCGTTTGATTTCTAAATACCGTCCAGAAGCTGATATCTTGGC
TGTAACATTCGATGAAATTACTCAAAAATCATTGATGCTTAACTGGGGTGTTATTCCAGTAGTTACTGAAAAACCAAGCT
CAACTGATGATATGTTTGATGTTGCTGAAAAAGTTGCATTGGAATCAGGTCTTGTAGAATCTGGTGACAACATTGTTATC
GTTGCTGGTGTTCCAGTAGGTACAGGTGGTACAAACACTATGCGTATCCGCACAGTAAAATAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDREASAKNIAQLIKEGANVFRFNFSHGDHAEQGERMDVVRMAEDLAG
QKVGFLLDTKGPEIRTELFEGDAKEYAYKTGEQIRVATKQGIKSTRDVIALNVAGALDVFDDVEVGKQVLVDDGKLGLRV
VDKDAEKREFIVEVENDGIIAKQKGVNIPYTKIPFPALAERDNADIRFGLEQGLNFIAISFVRTAKDVQEVRAICEETGN
GHVQLLAKIENQQGIDNIDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIITKVNAAGKVVVTATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPVESVRTMATIDKNAQTLLKEYGRLDSSTFDRSTKTEVVASAVKDATNSMDI
KLVVALTESGNTARLISKYRPEADILAVTFDEITQKSLMLNWGVIPVVTEKPSSTDDMFDVAEKVALESGLVESGDNIVI
VAGVPVGTGGTNTMRIRTVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 5e-73 43
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 2e-73 43
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 2e-73 43
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 1e-73 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006070047.1 pyruvate kinase VFG0479 Protein 7e-74 43