Gene Information

Name : SPNINV200_08750 (SPNINV200_08750)
Accession : YP_006066186.1
Strain : Streptococcus pneumoniae INV200
Genome accession: NC_017593
Putative virulence/resistance : Resistance
Product : Macrolide efflux transporter
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 887331 - 888794 bp
Length : 1464 bp
Strand : +
Note : -

DNA sequence :
ATGGAATTAATATTAAAAGCAAAAGACATTAGTGTGGAATTCAAAGGACACGATGTTTTAGATATAAATGAATTAGAAGT
ATATGATTATGACCGTATTGGTTTAGTAGGAGCAAATGGTGCAGGAAAAAGCACTTTATTCAAGGTACTTTTAGGAGAAT
TAATTCCCCCAGGATGTAAAATGAATCATCTGGGTGAACTTGCCTATATTCCCCAGTTGGACGAAGTAACTCTGCAGGAG
GAAAAAGATTTTGCGCTTGTAGGCAAGCTAGGTGTTGAGCAATTAAATATACAGACCATGAGCGGTGGTGAAGAAACAAG
GCTTAAAATAGCACAGGCCTTATCGGCACAGGTTCATGGTATTTTAGCGGATGAACCTACGAGCCATTTAGACCGTGAAG
GAATTGATTTTCTAATAGGACAGCTAAAATATTTTACAGGTGCACTGTTAGTTATTAGCCATGACCGCTATTTTCTTGAT
GAAATAGTAGATAAAATATGGGAACTGAAAGATGGCAAAATCACTGAGTATTGGGGAAACTATTCTGATTATCTTCGTCA
GAAAGAGGAAGAACGTAAGAGACAAGCTGCAGAATACGAACAATTTATTGCGGAACGTGCTCGATTGGAAAGGGCTGCGG
AGGAAAAGCGAAAACAGGCTCGTAAAATAGAACAGAAGGCAAAAGGTTCTTCAAAGAAAAAAAGTACTGAAGGCGGAGGG
CGTTTAGCTCATCAAAAATCAATAGGAAGTAAGGAAAAAAAGATGCATAATGCCGCTAAATCCCTAGAGAACAGGATTGC
GGCATTAGGAAAAGTAGAAGCTCCGGAAGGCATTCGCAGAATTCGTTTCAGGCAAAGTAAAGCATTGGAGCTCCATAATC
CATACCCTATAGTCGGTGCGGAAATTAATAAAGTATTTGGGGATAAGGCACTGTTTGAAAATGCATCTTTTCAAATTCCG
CTAGGAGCAAAAGTGGCATTAACGGGTGGTAATGGAACCGGAAAAACAACTTTAATCCAAATGATCTTAAACCATGAAGA
AGGAATTTCTATTTCACCTAAGGCAAAAATAGGTTACTTTGCACAGAATGGTTACAAGTACAACAGTAATCAGAATGTTA
TGGAGTTTATGCAGAAGGATTGTGATTACAATATATCAGAAATTCGTTCTGTGCTAGCATCTATGGGGTTCAAACAGAAC
GATATTGGAAAAAGCTTATCTGTTTTAAGCGGTGGAGAAATTATAAAATTGTTGCTTGCTAAAATGCTCATGGGTAGATA
TAACATCCTAATAATGGATGAACCCAGTAACTTCCTTGACATACCAAGTTTAGAGGCTTTGGAAATACTAATGAAGGAGT
ACACCGGAACTATCGTGTTTATCACCCACGATAAACGATTACTCGAAAATGTAGCTGATGTAGTTTATGAAATTAGAGAT
AAGAAAATTAAGCTGAAACATTAA

Protein sequence :
MELILKAKDISVEFKGHDVLDINELEVYDYDRIGLVGANGAGKSTLFKVLLGELIPPGCKMNHLGELAYIPQLDEVTLQE
EKDFALVGKLGVEQLNIQTMSGGEETRLKIAQALSAQVHGILADEPTSHLDREGIDFLIGQLKYFTGALLVISHDRYFLD
EIVDKIWELKDGKITEYWGNYSDYLRQKEEERKRQAAEYEQFIAERARLERAAEEKRKQARKIEQKAKGSSKKKSTEGGG
RLAHQKSIGSKEKKMHNAAKSLENRIAALGKVEAPEGIRRIRFRQSKALELHNPYPIVGAEINKVFGDKALFENASFQIP
LGAKVALTGGNGTGKTTLIQMILNHEEGISISPKAKIGYFAQNGYKYNSNQNVMEFMQKDCDYNISEIRSVLASMGFKQN
DIGKSLSVLSGGEIIKLLLAKMLMGRYNILIMDEPSNFLDIPSLEALEILMKEYTGTIVFITHDKRLLENVADVVYEIRD
KKIKLKH

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
msr(E) YP_005176244.1 macrolide efflux protein Not tested ICEPmu1 Protein 4e-137 62

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
SPNINV200_08750 YP_006066186.1 Macrolide efflux transporter NC_012469.1.7685970. Protein 0.0 98