Gene Information

Name : pyk (SPNINV200_08210)
Accession : YP_006066134.1
Strain : Streptococcus pneumoniae INV200
Genome accession: NC_017593
Putative virulence/resistance : Virulence
Product : putative pyruvate kinase
Function : -
COG functional category : -
COG ID : -
EC number : 2.7.1.40
Position : 835630 - 837135 bp
Length : 1506 bp
Strand : +
Note : -

DNA sequence :
ATGAACAAACGTGTAAAAATCGTTGCAACTTTGGGTCCTGCGGTAGAAATCCGTGGTGGTAAAAAATTCGGTGAGGACGG
ATACTGGGGTGAAAAACTTGATGTTGAAGCTTCAGCTAAAAACATTGCTAAATTGATTGAAGCTGGTGCTAACACATTCC
GATTCAACTTCTCACACGGCGACCACCAAGAACAAGGTGAGCGTATGGCAACTGTTAAACTTGCGGAAAAAATTGCAGGT
AAAAAAGTTGGTTTCCTTCTTGATACAAAAGGACCTGAAATCCGTACAGAATTGTTCGAAGGTGAAGCTAAAGAATATTC
ATACAAAACTAGTGAAAAAATTCGTGTTGCAACTAAACAAGGAATCAAATCAACTCGTGAAGTGATTGCGTTGAACGTTG
CTGGTGCTCTTGATATCTATGATGATGTTGAAGTTGGTCGTCAAGTTTTGGTTGACGATGGTAAACTTGGTCTTCGTGTG
GTTGCTAAAGATGATGCAACTCGTGAATTTGAAGTTGAAGTTGAAAACGATGGTATCATCGCTAAACAAAAAGGTGTGAA
CATCCCTAACACTAAAATTCCTTTCCCAGCTCTTGCTGAACGCGATAACGACGATATCCGTTTCGGTCTTGAACAAGGTA
TCAACTTCATCGCAATTTCATTCGTACGTACTGCAAAAGATGTGAACGAAGTTCGTGCAATCTGTGAAGAAACTGGAAAC
GGACATGTTCAATTGTTCGCTAAAATCGAAAACCAACAAGGTATCGATAACTTAGACGAAATCATCGAAGCAGCTGATGG
TATTATGATTGCTCGTGGTGATATGGGTATCGAAGTACCGTTCGAAATGGTTCCAGTTTATCAAAAAATGATTATCAAGA
AAGTCAATGCTGCAGGTAAAGTTGTTATCACTGCAACAAACATGCTTGAAACAATGACTGAAAAACCACGTGCAACTCGT
TCAGAAGTATCAGACGTATTCAACGCTGTTATCGACGGAACTGACGCTACAATGCTGTCAGGCGAGTCTGCAAACGGTAA
ATACCCACTCGAGTCAGTAACTACAATGGCTACAATCGACAAGAACGCTCAAGCTCTTCTTAATGAATACGGACGTCTTG
ATTCAGATTCATTTGAGCGTAACTCTAAGACAGAAGTAATGGCTTCTGCTGTTAAAGATGCTACTAGCTCAATGGATATC
AAATTGGTTGTAACTCTTACTAAGACAGGTCATACTGCACGTTTGATTTCTAAATACCGTCCAAATGCTGACATCTTAGC
ATTGACATTTGACGAATTGACAGAACGTGGCTTGATGTTGAACTGGGGTGTTATCCCAATGTTGACAGATGCTCCATCTT
CAACTGACGATATGTTCGAAATCGCTGAACGTAAAGCGGTAGAAGCAGGTCTCGTTGAGTCAGGCGATGATATCGTTATC
GTTGCTGGTGTGCCAGTAGGAGAAGCTGTTCGCACAAACACAATGCGTATCCGCACAGTACGTTAA

Protein sequence :
MNKRVKIVATLGPAVEIRGGKKFGEDGYWGEKLDVEASAKNIAKLIEAGANTFRFNFSHGDHQEQGERMATVKLAEKIAG
KKVGFLLDTKGPEIRTELFEGEAKEYSYKTSEKIRVATKQGIKSTREVIALNVAGALDIYDDVEVGRQVLVDDGKLGLRV
VAKDDATREFEVEVENDGIIAKQKGVNIPNTKIPFPALAERDNDDIRFGLEQGINFIAISFVRTAKDVNEVRAICEETGN
GHVQLFAKIENQQGIDNLDEIIEAADGIMIARGDMGIEVPFEMVPVYQKMIIKKVNAAGKVVITATNMLETMTEKPRATR
SEVSDVFNAVIDGTDATMLSGESANGKYPLESVTTMATIDKNAQALLNEYGRLDSDSFERNSKTEVMASAVKDATSSMDI
KLVVTLTKTGHTARLISKYRPNADILALTFDELTERGLMLNWGVIPMLTDAPSSTDDMFEIAERKAVEAGLVESGDDIVI
VAGVPVGEAVRTNTMRIRTVR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY1744 NP_456147.1 pyruvate kinase Not tested SPI-2 Protein 8e-80 44
pykF YP_216386.1 pyruvate kinase Not tested SPI-2 Protein 3e-80 44
pykF NP_805051.1 pyruvate kinase Not tested SPI-2 Protein 3e-80 44
pykF CAA68205.1 pyruvate kinase like protein Not tested SPI-2 Protein 2e-80 44

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pyk YP_006066134.1 putative pyruvate kinase VFG0479 Protein 1e-80 44