Gene Information

Name : TtJL18_0557 (TtJL18_0557)
Accession : YP_006058249.1
Strain : Thermus thermophilus JL-18
Genome accession: NC_017587
Putative virulence/resistance : Virulence
Product : ATP-dependent chaperone ClpB
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 490136 - 492700 bp
Length : 2565 bp
Strand : +
Note : PFAM: AAA domain (Cdc48 subfamily); C-terminal, D2-small domain, of ClpB protein; Clp amino terminal domain; ATPase family associated with various cellular activities (AAA); TIGRFAM: ATP-dependent chaperone ClpB

DNA sequence :
ATGAACCTGGAACGCTGGACCCAAGCCGCCCGCGAAGCCCTGGCCCAGGCGCAGGTCCTGGCCCAAAGGATGAAGCACCA
GGCCATAGACCTGCCCCACCTCTGGGCCGTCCTCCTGAAGGACGAGGGGGGCCTCGCCTGGCGCCTCTTGGAGAAGGCGG
GGGCCGACCCCAAGGCCTTGAAGGAGGCCCAGGAGCGGGAGCTTTCCCGCCTGCCCAAGGTGGAAGGGGCCGAGGTGGGC
CAATACCTCACGAGCCGCCTCTCCGGGGCCTTGAACCGGGCCGAGGCCCTGATGGAAGAGCTCAAGGACCGCTACGTAGC
GGTGGACACCCTGGTCCTGGCCCTGAGCGAGGCCACCCCGGGGCTTCCGGGCCTCGAGACCCTGAAAAAAGCCCTACAGG
AACTAAGGGGAGGGAAGACCGTGCAAACGGAACACGCGGAAAGCACCTACAACGCTTTGGAACAGTACGGCATTGATCTG
ACCAAGCTGGCCGCCGAGGGGAAGCTGGACCCGGTGATCGGCCGGGACGAGGAGATCCGACGCGTCATCCAGATCCTCCT
AAGGCGCACCAAGAACAACCCGGTCCTCATCGGCGAGCCCGGGGTGGGGAAGACGGCCATCGTGGAAGGCCTGGCCCAGC
GCATCGTCAAGGGGGATGTGCCCGAAGGCCTCAAGGGCAAGCGGATCGTCTCCTTGCAGATGGGCTCCCTCCTCGCCGGG
GCCAAGTACCGGGGCGAGTTTGAGGAGCGCTTGAAGGCGGTGATCCAGGAGGTGATCCAGTCCCAAGGGGAAGTCATCCT
CTTCATTGACGAGCTCCACACCGTGGTGGGGGCGGGCAAGGCCGAAGGCGCCGTGGACGCCGGCAACATGCTGAAGCCCG
CCTTAGCCCGGGGGGAGCTAAGGCTCATCGGGGCCACCACCCTGGACGAGTACCGGGAGATTGAGAAAGACCCCGCCCTA
GAACGGCGCTTCCAGCCCGTCTACGTGGACGAGCCCACGGTGGAGGAGACCATCTCCATCCTCCGGGGCCTCAAGGAGAA
GTACGAGGTCCACCACGGGGTGCGCATCTCCGACAGCGCCATCATCGCCGCCGCCACCCTCTCCCACCGGTACATCACGG
AAAGGCGCCTCCCCGACAAGGCCATTGACCTCATTGACGAGGCGGCGGCCCGCCTGCGCATGGCCCTGGAGAGCGCTCCC
GAGGAGATTGACGCCCTGGAGCGCAAGAAGCTCCAGCTGGAGATTGAGCGGGAGGCCCTGAAGAAGGAGAAGGACCCGGA
CTCCCAGGAGCGCCTCAAGGCCATTGAGGCCGAGATCGCCAAGCTCACGGAGGAGATCGCCAAGCTCCGGGCCGAGTGGG
AGAAGGAAAGGGAGATCCTGAGGAAGCTCCGCGAGGCCCAGCACCGCCTGGACGAGGTCAGGCGGGAGATTGAGCTCGCC
GAGCGGCAGTACGACCTGAACCGGGCCGCCGAGCTCCGCTACGGGGAGCTTCCCAAGCTGGAAGCCGAGGTGGAGGCCCT
TTCGGAAAAGCTCCGGGGCGCCCGCTTCGTCCGCCTCGAGGTCACCGAGGAGGACATCGCCGAGATCGTCTCCCGCTGGA
CCGGGATCCCCGTGGCGAAGCTTTTGGAAGGGGAAAGGGAAAAGCTCCTAAGGCTTGAGGAGGAGCTCCACAAGCGGGTG
GTGGGGCAGGACGAGGCCATAAGGGCCGTGGCCGACGCCATCCGCCGGGCCAGGGCCGGCCTAAAGGACCCGAACCGGCC
CATCGGAAGCTTCCTCTTCCTCGGGCCCACGGGGGTGGGGAAGACGGAGCTCGCCAAGACCCTGGCCGCCACCCTCTTTG
ACACCGAGGAAGCCATGATCCGCATCGACATGACGGAGTACATGGAGAAGCACGCCGTCTCCCGCCTCATCGGGGCCCCG
CCCGGCTACGTGGGCTACGAGGAGGGGGGGCAGCTCACCGAGGCGGTGCGGCGACGGCCTTACTCGGTCATCCTCTTTGA
CGAGATTGAGAAGGCCCACCCCGACGTCTTCAACATCCTCCTCCAGATCCTGGACGACGGCCGCCTCACCGACAGCCACG
GCCGCACCGTGGACTTCCGCAACACCGTCATCATCCTCACCTCCAACCTGGGGAGCCCCTTGATCCTCGAGGGCCTCCAG
AAGGGCTGGCCCTACGAAAGGATTCGGGACGAGGTCTTTAAGGTCTTGCAGCAGCACTTCCGCCCCGAGTTCCTGAACCG
CCTGGACGAGATCGTGGTCTTCCGGCCCCTCACCAAGGAGCAGATCCGCCAGATCGTGGAGATCCAGCTCTCCTACCTCC
GGGCCCGCCTCGCCGAGAAGCGCATCTCCCTGGAGCTCACCGAGGCCGCCAAGGACTTCCTGGCGGAAAGGGGCTACGAC
CCCGTCTTCGGGGCAAGGCCCTTGCGGCGGGTCATCCAGCGGGAGCTGGAGACGCCCCTCGCCCAGAAGATCCTGGCCGG
CGAGGTCAAGGAGGGGGACCGCGTGCAGGTGGACGTGGGGCCCGCGGGCCTCGTGTTTACCGTCCCCGCCCGGATAGAAG
CCTGA

Protein sequence :
MNLERWTQAAREALAQAQVLAQRMKHQAIDLPHLWAVLLKDEGGLAWRLLEKAGADPKALKEAQERELSRLPKVEGAEVG
QYLTSRLSGALNRAEALMEELKDRYVAVDTLVLALSEATPGLPGLETLKKALQELRGGKTVQTEHAESTYNALEQYGIDL
TKLAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAIVEGLAQRIVKGDVPEGLKGKRIVSLQMGSLLAG
AKYRGEFEERLKAVIQEVIQSQGEVILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPAL
ERRFQPVYVDEPTVEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAP
EEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAEIAKLTEEIAKLRAEWEKEREILRKLREAQHRLDEVRREIELA
ERQYDLNRAAELRYGELPKLEAEVEALSEKLRGARFVRLEVTEEDIAEIVSRWTGIPVAKLLEGEREKLLRLEEELHKRV
VGQDEAIRAVADAIRRARAGLKDPNRPIGSFLFLGPTGVGKTELAKTLAATLFDTEEAMIRIDMTEYMEKHAVSRLIGAP
PGYVGYEEGGQLTEAVRRRPYSVILFDEIEKAHPDVFNILLQILDDGRLTDSHGRTVDFRNTVIILTSNLGSPLILEGLQ
KGWPYERIRDEVFKVLQQHFRPEFLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKRISLELTEAAKDFLAERGYD
PVFGARPLRRVIQRELETPLAQKILAGEVKEGDRVQVDVGPAGLVFTVPARIEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 3e-97 44
aec27 YP_851418.1 ATPase Not tested PAI II APEC-O1 Protein 4e-99 43
aec27 AAQ96721.1 Aec27 Not tested AGI-1 Protein 3e-99 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TtJL18_0557 YP_006058249.1 ATP-dependent chaperone ClpB VFG2084 Protein 4e-98 41