Gene Information

Name : TtJL18_0322 (TtJL18_0322)
Accession : YP_006058019.1
Strain : Thermus thermophilus JL-18
Genome accession: NC_017587
Putative virulence/resistance : Virulence
Product : response regulator with CheY-like receiver domain and winged-helix DNA-binding domain
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 289773 - 290450 bp
Length : 678 bp
Strand : -
Note : PFAM: Response regulator receiver domain; Transcriptional regulatory protein, C terminal

DNA sequence :
ATGAAGGTCCTTTTGGTGGACGACGACCCGGCCATCCTCGAGGTCCTCGGGGCCTTTCTGAGGGGGGCCGGGTTTGAGGT
CTTGGAGGCGGAGGACGGGGAAAAGGCCTTGGAGCTCTTTCCCCAGGCCGATCTGGTCATCCTGGACCTGATGCTCCCCA
AGGTGGGAGGCCTCGAGGTGGCCCGCCTCATCCGCCAGGAGCGCCCCGAGCTTCCCCTCCTCATCCTCACCGCCAAGGGG
GAGGAGGAGGACCGGGTCCTGGGCCTGGAGCTTGGGGCGGACGATTACGTGGTCAAGCCCTTCAGCCCCAGGGAGGTGGT
GGCCCGGGTCAAGGCCCTGTTGCGCCGAGCCGGGCTAAGGGAGGAGCTCGTCTACGGTCCCTTGCGCCTCCTCCCCACCC
GGCGGGAGGCCTACCTGGCGGGAAAGCCCCTCCCCCTCTCCCGGCTGGAGTTTGACCTCCTCTTAACCCTCGCCCAGCAC
CCGGGGGTGGTTTTCAGCCGGGAGAGGCTTCTGGAAAAGGTCTGGGGGCCCGGCTTTCCCGGGGTGGACCGGGTAGTGGA
CGTCCACATCGCCGCCCTTCGGAAGAAGCTCGGGGACGACCCGGAAAACCCCCGCTTCCTGGAGACGGTGCGGGGCGTAG
GCTACCGCTTCAAGGACCTGGATGCGCCTCTTCCTTAA

Protein sequence :
MKVLLVDDDPAILEVLGAFLRGAGFEVLEAEDGEKALELFPQADLVILDLMLPKVGGLEVARLIRQERPELPLLILTAKG
EEEDRVLGLELGADDYVVKPFSPREVVARVKALLRRAGLREELVYGPLRLLPTRREAYLAGKPLPLSRLEFDLLLTLAQH
PGVVFSRERLLEKVWGPGFPGVDRVVDVHIAALRKKLGDDPENPRFLETVRGVGYRFKDLDAPLP

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
c3565 NP_755440.1 response regulator Not tested PAI I CFT073 Protein 5e-37 45
unnamed CAD42044.1 hypothetical protein Not tested PAI II 536 Protein 2e-37 44
armR AAN62112.1 putative response-regulator ArmR Not tested PAGI-2(C) Protein 1e-19 41
copR NP_460069.2 transcriptional regulatory protein YedW Not tested SPI-5 Protein 1e-25 41
copR AAC33719.1 regulatory protein CopR Not tested SPI-5 Protein 2e-25 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002952.2859905.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002758.1121668.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_009641.5332272.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_013450.8614421.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_003923.1003749.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_007793.3914279.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_007622.3794472.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002745.1124361.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_009782.5559369.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002951.3237708.p0 Protein 8e-42 48
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_012469.1.7685629. Protein 3e-35 45
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain HE999704.1.gene2815. Protein 7e-45 45
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain AE000516.2.gene3505. Protein 8e-35 45
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_012469.1.7686381. Protein 9e-43 44
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain AE016830.1.gene1681. Protein 6e-41 44
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP001918.1.gene5135. Protein 2e-24 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP000647.1.gene4257. Protein 4e-28 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP001138.1.gene4273. Protein 3e-28 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP004022.1.gene3215. Protein 5e-31 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002695.1.915041.p Protein 1e-27 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain BAC0533 Protein 4e-28 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP000034.1.gene3834. Protein 1e-27 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP000034.1.gene2186. Protein 1e-31 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain NC_002695.1.916589.p Protein 7e-32 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain BAC0039 Protein 1e-31 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain BAC0197 Protein 2e-23 42
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP000647.1.gene2531. Protein 4e-31 42
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP001138.1.gene2239. Protein 1e-32 42
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain BAC0596 Protein 1e-32 42
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP001918.1.gene3444. Protein 7e-31 42
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain CP000675.2.gene1535. Protein 2e-34 41
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain BAC0347 Protein 8e-23 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1702 Protein 2e-37 45
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1563 Protein 9e-38 44
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG1389 Protein 3e-27 43
TtJL18_0322 YP_006058019.1 response regulator with CheY-like receiver domain and winged-helix DNA-binding domain VFG0596 Protein 4e-26 41