Gene Information

Name : TtJL18_0246 (TtJL18_0246)
Accession : YP_006057947.1
Strain : Thermus thermophilus JL-18
Genome accession: NC_017587
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : -
COG ID : -
EC number : -
Position : 220046 - 222682 bp
Length : 2637 bp
Strand : +
Note : PFAM: tRNA synthetases class I (I, L, M and V); Anticodon-binding domain; TIGRFAM: leucyl-tRNA synthetase, eubacterial and mitochondrial family

DNA sequence :
ATGGAGAAGTACAACCCGCACGCCATCGAAGCCAAGTGGCAGCGCTTCTGGGAGGAGAAGGGGTTCATGAAGGCCAAGGA
CCTCCCGGGGGGCCGGGGGAAGCAGTACGTCCTCGTCATGTTCCCCTACCCCTCGGGGGACCTGCACATGGGCCACCTGA
AGAACTACACCATGGGGGACGTCCTGGCCCGCTTCCGCCGGATGCAGGGCTACGAGGTCCTCCACCCCATGGGCTGGGAC
GCTTTTGGCCTTCCGGCGGAGAACGCCGCCCTGAAGTTCGGCGTCCACCCCAAGGACTGGACCTACGCGAACATCCGCCA
GGCCAAGGAGAGCCTCCGGCTCATGGGCATCCTCTACGACTGGGACCGGGAGGTCACCACCTGCGAGCCCGAGTACTACC
GCTGGAACCAGTGGATCTTCCTCAAGATGTGGGAAAAGGGCCTGGCCTACCGGGCGAAGGGCCTCGTCAACTGGTGCCCC
AAGTGCCAGACGGTCCTCGCCAACGAGCAGGTGGTGGAGGGGCGGTGCTGGCGGCACGAGGACACCCCGGTGGAGAAGCG
GGAGCTGGAGCAGTGGTACCTGCGCATCACCGCCTACGCCGAGAGGCTTCTTAAGGACCTCGAGGGCCTCAACTGGCCCG
AGAAGGTCAAGGCCATGCAAAGGGCCTGGATCGGCCGCTCCGAGGGGGCGGAGATCCTCTTCCCCGTGGAGGGGAAGGAG
GTGAGGATCCCCGTCTTCACCACCCGCCCCGACACCCTCTTTGGGGCCACCTTCCTCGTGCTCGCCCCGGAGCACCCCCT
GACCCTGGAGCTCGCCGCCCCGGAGAAGCGGGAGGAGGTCCTGGCCTACGTGGAGGCCGCCAAGCGCAAGACGGAGATTG
AGCGCCAGGCGGAAGGCAGGGAGAAGACCGGGGTCTTCCTGGGGGCCTACGCCCTAAACCCCGCCACGGGGGAGAGGATC
CCCATCTGGACCGCCGACTACGTGCTCTTTGGCTACGGCACCGGGGCCATCATGGCTGTGCCCGCCCACGACCAGCGGGA
CTTTGAGTTCGCCAAGAAGTTTGGCCTTCCCATCAAGAAGGTGATTGAGCGGCCCGGCGAGCCCCTCCCCGAGCCCCTGG
AAAGGGCCTACGAGGAGCCCGGGATCATGGTGAACTCCGGGCCCTTTGACGGCACGCCAAGCGAGGAGGGGAAGAGGAAG
GTCATCGCCTGGCTGGAGGAGAAGGGCCTGGGCAAGGGCCGGGTCACCTACCGCCTCCGGGACTGGCTCATCAGCCGCCA
GCGCTACTGGGGGACCCCCATCCCCATGGTCCACTGCGAGGCCTGCGGGGTGGTCCCCGTCCCTGAGGAGGAGCTTCCCG
TCCTCCTCCCCGACCTCAAGGACATAGAGGACATCCGCCCTAAGGGGAAAAGCCCCTTGGAGGCCCACCCCGAGTTCTAC
GAGACCACCTGCCCCAAGTGCGGTGGCCCCGCCAAGCGGGACACCGACACCATGGACACCTTCTTTGACTCCAGCTGGTA
CTACCTCCGCTACACCGATCCCAAAAACGACCGCCTCCCCTTTGACCCCGAAAAGGCCAACGCCTGGATGCCCGTGGACC
AGTACATCGGCGGGGTGGAGCACGCCGTGCTCCACCTCCTCTACAGCCGCTTCTTCACCAAGTTCCTCCACGACCTGGGG
ATGGTGAAGGTGGAGGAGCCTTTTAAGGGCCTCTTCACCCAGGGCATGGTCATGGCCTGGACGGACTTCGGCCCCGTAGA
GGTGGAAGGAAGTGCGGTGCGCCTCCCCGAGCCCACCCGCATCCGGCTGGAGATCCCGGAAAGCGAGCTTTCCCTGGAGG
ACGTGAGGAAGATGGGGGCCGAGCTCAGGCCCCACGAGGACGGCACCCTCCACCTTTGGAAGCCCGCCGTCATGAGCAAG
TCCAAGGGCAACGGCGTCATGGTGGGGCCCTTCGTGAAGGAGCAGGGGGCGGACATCGCCCGCATCACCATCCTCTTCGC
CGCGCCCCCGGAGAACGAGATGGTCTGGACCGAGGAGGGGGTCCAGGGGGCCTGGCGCTTCCTGAACCGCATCTACCGGC
GGGTGGCCGAGGACCGGGAGGCCCTTTTGGCGACGAGCGGGGTCTTCCAGGCCGAGGCTTTAGAGGGGAAGGACCGGGAG
CTTTACGGGAAGCTGCACGAGACCCTGAAGAAGGTCACGGAGGACCTCGAGGCCCTGCGCTTCAACACCGCCATCGCCGC
CCTCATGGAGTTCCTGAACGCCCTCTACGAGTACCGCAAGGACCGCCCCGTGACCCCGGTCTACCGCACCGCCATTCGCT
ACTACCTGCAGATGCTCTTCCCCTTCGCCCCCCACCTCGCCGAGGAGCTTTGGCACTGGTTCTGGCCGGATAGCCTTTTT
GAGGCGGGCTGGCCCGAGCTGGACGAGAAGGCCCTGGAGAAGGACGTGGTGGAGGTGGCCGTCCAGGTGAACGGGCGGGT
GCGGGGGACGATCCGGATCCCCAAGGACGCCCCCCTGGAGGTGGCGCGGGCCGAGGCCCTTAAGGTGCGAAACGTCCAGG
CCCACCTCGAGGGCAAGGAGGTGGTGAAGGAGATCTACGTCCCGGGGAAGATCCTCAACCTGGTAGTGCGGGGGTAG

Protein sequence :
MEKYNPHAIEAKWQRFWEEKGFMKAKDLPGGRGKQYVLVMFPYPSGDLHMGHLKNYTMGDVLARFRRMQGYEVLHPMGWD
AFGLPAENAALKFGVHPKDWTYANIRQAKESLRLMGILYDWDREVTTCEPEYYRWNQWIFLKMWEKGLAYRAKGLVNWCP
KCQTVLANEQVVEGRCWRHEDTPVEKRELEQWYLRITAYAERLLKDLEGLNWPEKVKAMQRAWIGRSEGAEILFPVEGKE
VRIPVFTTRPDTLFGATFLVLAPEHPLTLELAAPEKREEVLAYVEAAKRKTEIERQAEGREKTGVFLGAYALNPATGERI
PIWTADYVLFGYGTGAIMAVPAHDQRDFEFAKKFGLPIKKVIERPGEPLPEPLERAYEEPGIMVNSGPFDGTPSEEGKRK
VIAWLEEKGLGKGRVTYRLRDWLISRQRYWGTPIPMVHCEACGVVPVPEEELPVLLPDLKDIEDIRPKGKSPLEAHPEFY
ETTCPKCGGPAKRDTDTMDTFFDSSWYYLRYTDPKNDRLPFDPEKANAWMPVDQYIGGVEHAVLHLLYSRFFTKFLHDLG
MVKVEEPFKGLFTQGMVMAWTDFGPVEVEGSAVRLPEPTRIRLEIPESELSLEDVRKMGAELRPHEDGTLHLWKPAVMSK
SKGNGVMVGPFVKEQGADIARITILFAAPPENEMVWTEEGVQGAWRFLNRIYRRVAEDREALLATSGVFQAEALEGKDRE
LYGKLHETLKKVTEDLEALRFNTAIAALMEFLNALYEYRKDRPVTPVYRTAIRYYLQMLFPFAPHLAEELWHWFWPDSLF
EAGWPELDEKALEKDVVEVAVQVNGRVRGTIRIPKDAPLEVARAEALKVRNVQAHLEGKEVVKEIYVPGKILNLVVRG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 2e-156 44